17513-1-AP

antibody from Proteintech Group

Targeting: KRT7 CK7, K2C7, K7, SCL

Provider product page for 17513-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [24]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]
Immunohistochemistry [2]

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Product number: 17513-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#17513-1-AP, RRID:AB_2134468
Product name: Cytokeratin 7-specific antibody
Antibody type: Polyclonal
Description: Cytokeratin 7-specific antibody (Cat. #17513-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

KRT7 protein structure - 17513-1-AP shown in red.

Submitted references Decreased USP2a Expression Inhibits Trophoblast Invasion and Associates With Recurrent Miscarriage.

Wang J, Ding J, Zhang S, Chen X, Yan S, Zhang Y, Yin T
Frontiers in immunology 2021;12:717370

Integrative Genomic Analysis of Gemcitabine Resistance in Pancreatic Cancer by Patient-derived Xenograft Models.

Yang G, Guan W, Cao Z, Guo W, Xiong G, Zhao F, Feng M, Qiu J, Liu Y, Zhang MQ, You L, Zhang T, Zhao Y, Gu J
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Jun 15;27(12):3383-3396

A novel lymphatic pattern promotes metastasis of cervical cancer in a hypoxic tumour-associated macrophage-dependent manner.

Chen XJ, Wei WF, Wang ZC, Wang N, Guo CH, Zhou CF, Liang LJ, Wu S, Liang L, Wang W
Angiogenesis 2021 Aug;24(3):549-565

A Novel Molecule in Human Cyclic Endometrium: LncRNA TUNAR Is Involved in Embryo Implantation.

Wang Y, Hu S, Yao G, Zhu Q, He Y, Lu Y, Qi J, Xu R, Ding Y, Li J, Li X, Sun Y
Frontiers in physiology 2020;11:587448

FoxM1 promotes the migration of ovarian cancer cell through KRT5 and KRT7.

Zhang Z, Tu K, Liu F, Liang M, Yu K, Wang Y, Luo Y, Yang B, Qin Y, He D, Jiang G, Huang O, Zou Y
Gene 2020 Oct 5;757:144947

Hepatic stem cell Numb gene is a potential target of Huang Qi Decoction against cholestatic liver fibrosis.

Xu W, Xu YN, Zhang X, Xu Y, Jian X, Chen JM, Chen GF, Zhang H, Liu P, Mu YP
Scientific reports 2020 Oct 15;10(1):17486

The role of ERK-RSK signaling in the proliferation of intrahepatic biliary epithelial cells exposed to microcystin-leucine arginine.

Yan M, Shen G, Zhou Y, Meng X, Han X
Biochemical and biophysical research communications 2020 Jan 8;521(2):492-498

SPARCL1 impedes trophoblast migration and invasion by down-regulating ERK phosphorylation and AP-1 production and altering EMT-related molecule expression.

Liu X, Zhao J, Luan X, Li S, Zhai J, Liu J, Du Y
Placenta 2020 Jan 1;89:33-41

Epiregulin promotes trophoblast epithelial-mesenchymal transition through poFUT1 and O-fucosylation by poFUT1 on uPA.

Cui X, Wang H, Li Y, Chen T, Liu S, Yan Q
Cell proliferation 2020 Feb;53(2):e12745

FasL on decidual macrophages mediates trophoblast apoptosis: A potential cause of recurrent miscarriage.

Ding J, Yin T, Yan N, Cheng Y, Yang J
International journal of molecular medicine 2019 Jun;43(6):2376-2386

Cytokeratin expression in epidermal stem cells in skin adnexal tumors.

Zhou X, Li G, Wang D, Sun X, Li X
Oncology letters 2019 Jan;17(1):927-932

Toll-like receptor 4 shRNA attenuates lipopolysaccharide-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells in rats.

Tang S, Jiang X, Wu L, Chen S, Chen L, Jiang J, Yan P, Wang F, Tu K, Wang D, Gu J, Zhao L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1210-1217

AP1 mediates uPA/uPAR induced FUT4 expression and trophoblast invasion.

Zheng Q, Yang Y, Cui X, Zhang D, Liu S, Yan Q
Journal of cellular biochemistry 2018 Aug;119(8):6442-6451

Novel roles of DC-SIGNR in colon cancer cell adhesion, migration, invasion, and liver metastasis.

Na H, Liu X, Li X, Zhang X, Wang Y, Wang Z, Yuan M, Zhang Y, Ren S, Zuo Y
Journal of hematology & oncology 2017 Jan 21;10(1):28

Up-regulation of CD81 inhibits cytotrophoblast invasion and mediates maternal endothelial cell dysfunction in preeclampsia.

Shen L, Diao Z, Sun HX, Yan GJ, Wang Z, Li RT, Dai Y, Wang J, Li J, Ding H, Zhao G, Zheng M, Xue P, Liu M, Zhou Y, Hu Y
Proceedings of the National Academy of Sciences of the United States of America 2017 Feb 21;114(8):1940-1945

DC - SIGNR by influencing the lncRNA HNRNPKP2 upregulates the expression of CXCR4 in gastric cancer liver metastasis.

Zhang Y, Zhang Q, Zhang M, Yuan M, Wang Z, Zhang J, Zhou X, Zhang Y, Lin F, Na H, Ren S, Zuo Y
Molecular cancer 2017 Apr 13;16(1):78

Role of thioredoxin reductase 1 in dysplastic transformation of human breast epithelial cells triggered by chronic oxidative stress.

Dong C, Zhang L, Sun R, Liu J, Yin H, Li X, Zheng X, Zeng H
Scientific reports 2016 Nov 15;6:36860

Leukemia inhibitory factor promote trophoblast invasion via urokinase-type plasminogen activator receptor in preeclampsia.

Zheng Q, Dai K, Cui X, Yu M, Yang X, Yan B, Liu S, Yan Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:102-108

Curcumin improves LPS-induced preeclampsia-like phenotype in rat by inhibiting the TLR4 signaling pathway.

Gong P, Liu M, Hong G, Li Y, Xue P, Zheng M, Wu M, Shen L, Yang M, Diao Z, Hu Y
Placenta 2016 May;41:45-52

Resistin reinforces interferon λ-3 to eliminate hepatitis C virus with fine-tuning from RETN single-nucleotide polymorphisms.

Chang ML, Liang KH, Ku CL, Lo CC, Cheng YT, Hsu CM, Yeh CT, Chiu CT
Scientific reports 2016 Aug 1;6:30799

Low doses of CMV induce autoimmune-mediated and inflammatory responses in bile duct epithelia of regulatory T cell-depleted neonatal mice.

Wen J, Xiao Y, Wang J, Pan W, Zhou Y, Zhang X, Guan W, Chen Y, Zhou K, Wang Y, Shi B, Zhou X, Yuan Z, Cai W
Laboratory investigation; a journal of technical methods and pathology 2015 Feb;95(2):180-92

Pregnancy-associated plasma protein A up-regulated by progesterone promotes adhesion and proliferation of trophoblastic cells.

Wang J, Liu S, Qin HM, Zhao Y, Wang XQ, Yan Q
International journal of clinical and experimental pathology 2014;7(4):1427-37

Noninvasive urine-derived cell lines derived from neurological genetic patients.

Zhang QJ, He J, Ni W, Lin X, Yao XP, Lin MT, Murong SX, Wang N, Chen WJ
Neuroreport 2013 Mar 6;24(4):161-6

Pulmonary tumors associated with the JC virus T-antigen in a transgenic mouse model.

Noguchi A, Kikuchi K, Ohtsu T, Yoshiwara M, Nakamura Y, Miyagi Y, Zheng H, Takano Y
Oncology reports 2013 Dec;30(6):2603-8

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: HeLa cells were subjected to SDS PAGE followed by western blot with 17513-1-AP(KRT7-Specific antibody) at dilution of 1:300
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunofluorescent analysis of HepG2 cells, using KRT7 antibody 17513-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human lung cancer using 17513-1-AP(KRT7-Specific antibody) at dilution of 1:50 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human lung cancer using 17513-1-AP(KRT7-Specific antibody) at dilution of 1:50 (under 40x lens)
Sample type: tissue