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- Product number
- NBP1-46191 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-46191, RRID:AB_10009423
- Product name
- Rabbit Polyclonal PSMD11 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction.
6-bromo-indirubin-3'-oxime (6BIO), a Glycogen synthase kinase-3β inhibitor, activates cytoprotective cellular modules and suppresses cellular senescence-mediated biomolecular damage in human fibroblasts.
The Indirubin Derivative 6-Bromoindirubin-3'-Oxime Activates Proteostatic Modules, Reprograms Cellular Bioenergetic Pathways, and Exerts Antiaging Effects.
Inhibition of Proteasome Activity Induces Formation of Alternative Proteasome Complexes.
Nath SR, Yu Z, Gipson TA, Marsh GB, Yoshidome E, Robins DM, Todi SV, Housman DE, Lieberman AP
The Journal of clinical investigation 2018 Aug 1;128(8):3630-3641
The Journal of clinical investigation 2018 Aug 1;128(8):3630-3641
6-bromo-indirubin-3'-oxime (6BIO), a Glycogen synthase kinase-3β inhibitor, activates cytoprotective cellular modules and suppresses cellular senescence-mediated biomolecular damage in human fibroblasts.
Sklirou AD, Gaboriaud-Kolar N, Papassideri I, Skaltsounis AL, Trougakos IP
Scientific reports 2017 Sep 15;7(1):11713
Scientific reports 2017 Sep 15;7(1):11713
The Indirubin Derivative 6-Bromoindirubin-3'-Oxime Activates Proteostatic Modules, Reprograms Cellular Bioenergetic Pathways, and Exerts Antiaging Effects.
Tsakiri EN, Gaboriaud-Kolar N, Iliaki KK, Tchoumtchoua J, Papanagnou ED, Chatzigeorgiou S, Tallas KD, Mikros E, Halabalaki M, Skaltsounis AL, Trougakos IP
Antioxidants & redox signaling 2017 Nov 10;27(14):1027-1047
Antioxidants & redox signaling 2017 Nov 10;27(14):1027-1047
Inhibition of Proteasome Activity Induces Formation of Alternative Proteasome Complexes.
Welk V, Coux O, Kleene V, Abeza C, Trümbach D, Eickelberg O, Meiners S
The Journal of biological chemistry 2016 Jun 17;291(25):13147-59
The Journal of biological chemistry 2016 Jun 17;291(25):13147-59
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: PSMD11 Antibody [NBP1-46191] - Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 mcg), and mouse NIH3T3 (M; 50 mcg) cells. Affinity purified rabbit anti-PSMD11 antibody used for WB at 0.04 mcg/ml (A) and 0.4 mcg/ml (B) and used for IP at 3 mcg/mg lysate. PSMD11 was also immunoprecipitated by rabbit anti-PSMD11 antibody NBP1-46192, which recognizes a downstream epitope.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: PSMD11 Antibody [NBP1-46191] - Treatment of human skin fibroblasts with 6BIO activated proteostatic modules. Representative immunoblot analyses of the autophagy-related Beclin1 and the 26S proteasome subunits Rpn6 (PSMD11), Rpt6, alpha7 and beta5 expression levels after cell exposure to the shown concentrations of 6BIO for 36 h. Image collected and cropped by CiteAb from the following publication (http://www.nature.com/articles/s41598-017-11662-7), licensed under a CC-BY licence.
