11-7541-25

antibody from ABEOMICS Inc.
Targeting: CALB2 CAL2
Provider product page for 11-7541-25

Antibody data

Product number
11-7541-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-Calretinin Antibody
Antibody type
Polyclonal
Description
Calretinin is a 29-kD intracellular, vitamin D-dependent calcium binding protein that likely has multiple functional roles including intracellular calcium buffering and message targeting. This protein is a member of the EF-hand family of calcium-binding proteins and first identified in the central nervous system. It has also been identified in a wide variety of non-neural cells, both neoplastic and non-neoplastic. In the oncologic arena calretinin is most commonly used as part of a panel in the separation of pleural mesothelioma from poorly differentiated pulmonary adenocarcinomas. While in most cases highly sensitive and specific for mesothelial origin, calretinin positivity has been reported in carcinomas arising in a myriad of other tissues including ovary, testis, adrenal cortex, colon, breast, sinonasal tract, thymus, skin and even soft tissue.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant Calret
inin protein (amino acids 4-238) wa
s used as the immunogen for this an
tibody.
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
CALB2 protein structure - 11-7541-25 shown in red.