Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations [0]
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- Product number
- M01689 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Somatostatin Receptor 2 SSTR2 Rabbit Monoclonal Antibody
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody for Somatostatin R2/SSTR2 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IP, IHC, WB. Reactive species: Human, Mouse, Rat Somatostatin R2/SSTR2 information: Molecular Weight: 41333 MW; Subcellular Localization: Cell membrane; Multi-pass membrane protein. Cytoplasm. Located mainly at the cell surface under basal conditions. Agonist stimulation results in internalization to the cytoplasm; Tissue Specificity: Expressed in both pancreatic alpha- and beta- cells (at protein level). Expressed at higher levels in the pancreas than other somatostatin receptors. Also expressed in the cerebrum and kidney and, in lesser amounts, in the jejunum, colon and liver. In the developing nervous system, expressed in the cortex where it is located in the preplate at early stages and is enriched in the outer part of the germinal zone at later stages. In the cerebellum, expressed in the deep part of the external granular layer at gestational week 19. This pattern persists until birth but disappears at adulthood.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antibody clone number
- CIF-19
- Vial size
- 100ug/vial
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Submitted references Upregulation of Somatostatin Receptor Type 2 Improves 177Lu-DOTATATE Therapy in Receptor-Deficient Pancreatic Neuroendocrine Tumor Model.
SOM230 combined with celecoxib prolongs the survival in nude mice with HepG-2 xenografts.
Sharma R, Earla B, Baidoo KE, Zeiger MA, Madigan JP, Escorcia FE, Sadowski SM
Molecular cancer therapeutics 2023 Sep 5;22(9):1052-1062
Molecular cancer therapeutics 2023 Sep 5;22(9):1052-1062
SOM230 combined with celecoxib prolongs the survival in nude mice with HepG-2 xenografts.
Xie Y, Chen S, Wang CH, Tang CW
Cancer biology & therapy 2011 Jul 1;12(1):86-92
Cancer biology & therapy 2011 Jul 1;12(1):86-92
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