67240-1-Ig

antibody from Proteintech Group

Targeting: NQO1 DHQU, DIA4, DTD, NMOR1, QR1

Provider product page for 67240-1-Ig

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Product number: 67240-1-Ig - Provider product page
Provider: Proteintech Group
Product name: NQO1 antibody
Antibody type: Monoclonal
Description: NQO1 antibody (Cat. #67240-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Rat, mouse, pig and has been validated for the following applications: IHC, WB,ELISA.
Reactivity: Human, Mouse, Rat, Porcine
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: 1E5G7
Vial size: 20ul, 150ul

NQO1 protein structure - 67240-1-Ig shown in red.

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Glutathione Induces Keap1 S-Glutathionylation and Mitigates Oscillating Glucose-Induced β-Cell Dysfunction by Activating Nrf2.

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Capsaicin Enhanced the Efficacy of Photodynamic Therapy Against Osteosarcoma via a Pro-Death Strategy by Inducing Ferroptosis and Alleviating Hypoxia.

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Small (Weinheim an der Bergstrasse, Germany) 2024 Jun;20(26):e2306916

Nrf2 mediates the effects of shionone on silica-induced pulmonary fibrosis.

Wang G, Xie W, Deng L, Huang X, Sun M, Liu W, Tang S
Chinese medicine 2024 Jun 19;19(1):88

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Behavioural brain research 2024 Jul 9;469:115006

Gynura divaricata (L.) DC. promotes diabetic wound healing by activating Nrf2 signaling in diabetic rats.

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Journal of ethnopharmacology 2024 Apr 6;323:117638

Protective Effects of Isoliquiritigenin and Licochalcone B on the Immunotoxicity of BDE-47: Antioxidant Effects Based on the Activation of the Nrf2 Pathway and Inhibition of the NF-κB Pathway.

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Antioxidants (Basel, Switzerland) 2024 Apr 10;13(4)

Myricetin attenuates hypoxic-ischemic brain damage in neonatal rats via NRF2 signaling pathway.

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Frontiers in pharmacology 2023;14:1134464

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Puerarin protects against acetaminophen-induced oxidative damage in liver through activation of the Keap1/Nrf2 signaling pathway.

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CDDO-Me ameliorates podocyte injury through anti-oxidative stress and regulation of actin cytoskeleton in adriamycin nephropathy.

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Neuroprotective effects of Lycium barbarum polysaccharide on light-induced oxidative stress and mitochondrial damage via the Nrf2/HO-1 pathway in mouse hippocampal neurons.

Yang Y, Yu L, Zhu T, Xu S, He J, Mao N, Liu Z, Wang D
International journal of biological macromolecules 2023 Nov 1;251:126315

MAGL inhibition relieves synovial inflammation and pain via regulating NOX4-Nrf2 redox balance in osteoarthritis.

Li X, Tao H, Zhou J, Zhang L, Shi Y, Zhang C, Sun W, Chu M, Chen K, Gu C, Yang X, Geng D, Hao Y
Free radical biology & medicine 2023 Nov 1;208:13-25

Novel Hydrogen Sulfide Hybrid Derivatives of Keap1-Nrf2 Protein-Protein Interaction Inhibitor Alleviate Inflammation and Oxidative Stress in Acute Experimental Colitis.

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Elsholtzia bodinieri Vaniot ameliorated acute lung injury in mice by regulating pyroptosis, inflammation, oxidative stress and macrophage polarization.

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Effects of protocatechuic acid on antioxidant capacity, mitochondrial biogenesis and skeletal muscle fiber transformation.

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The Journal of nutritional biochemistry 2023 Jun;116:109327

Ginsenoside Rh2 inhibits CBP/p300-mediated FOXO3a acetylation and epilepsy-induced oxidative damage via the FOXO3a-KEAP1-NRF2 pathway.

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European journal of pharmacology 2023 Feb 5;940:175391

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Nobiletin Ameliorates Hepatic Lipid Deposition, Oxidative Stress, and Inflammation by Mechanisms That Involve the Nrf2/NF-κB Axis in Nonalcoholic Fatty Liver Disease.

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Journal of agricultural and food chemistry 2023 Dec 20;71(50):20105-20117

HMSCs exosome-derived miR-199a-5p attenuates sulfur mustard-associated oxidative stress via the CAV1/NRF2 signalling pathway.

Gong C, Gu Z, Zhang X, Xu Q, Mao G, Pei Z, Meng W, Cen J, Liu J, He X, Sun M, Xiao K
Journal of cellular and molecular medicine 2023 Aug;27(15):2165-2182

Retinoic acid protects against lipopolysaccharide-induced ferroptotic liver injury and iron disorders by regulating Nrf2/HO-1 and RARβ signaling.

Lai X, Wu A, Bing Y, Liu Y, Luo J, Yan H, Zheng P, Yu J, Chen D
Free radical biology & medicine 2023 Aug 20;205:202-213

TNFAIP2 confers cisplatin resistance in head and neck squamous cell carcinoma via KEAP1/NRF2 signaling.

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Journal of experimental & clinical cancer research : CR 2023 Aug 1;42(1):190

A small-molecule inhibitor of Keap1-Nrf2 interaction attenuates sepsis by selectively augmenting the antibacterial defence of macrophages at infection sites.

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EBioMedicine 2023 Apr;90:104480

Activation of NRF2 Signaling Pathway Delays the Progression of Hyperuricemic Nephropathy by Reducing Oxidative Stress.

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Antioxidants (Basel, Switzerland) 2023 Apr 28;12(5)

4-Octyl itaconate attenuates LPS-induced acute kidney injury by activating Nrf2 and inhibiting STAT3 signaling.

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Molecular medicine (Cambridge, Mass.) 2023 Apr 24;29(1):58

Variable p53/Nrf2 crosstalk contributes to triptolide-induced hepatotoxic process.

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Toxicology letters 2023 Apr 15;379:67-75

Aristolochic acid induces an inflammatory response with prostaglandin E2 production and apoptosis in NRK-52E proximal tubular cells.

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Toxicology letters 2023 Apr 1;378:39-50

Using Collagen Peptides From the Skin of Monkfish (Lophius litulon) to Ameliorate Kidney Damage in High-Fat Diet Fed Mice by Regulating the Nrf2 Pathway and NLRP3 Signaling.

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Frontiers in nutrition 2022;9:798708

Xuesaitong Combined with Dexmedetomidine Improves Cerebral Ischemia-Reperfusion Injury in Rats by Activating Keap1/Nrf2 Signaling and Mitophagy in Hippocampal Tissue.

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Oxidative medicine and cellular longevity 2022;2022:5126042

Sulforaphane Ameliorates Limb Ischemia/Reperfusion-Induced Muscular Injury in Mice by Inhibiting Pyroptosis and Autophagy via the Nrf2-ARE Pathway.

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Shikonin Attenuates Cochlear Spiral Ganglion Neuron Degeneration by Activating Nrf2-ARE Signaling Pathway.

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Frontiers in molecular neuroscience 2022;15:829642

Cryptotanshinone protects skin cells from ultraviolet radiation-induced photoaging via its antioxidant effect and by reducing mitochondrial dysfunction and inhibiting apoptosis.

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Frontiers in pharmacology 2022;13:1036013

Eugenol Attenuates Transmissible Gastroenteritis Virus-Induced Oxidative Stress and Apoptosis Via ROS-NRF2-ARE Signaling.

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Antioxidants (Basel, Switzerland) 2022 Sep 18;11(9)

Ethanol extracts of Rhaponticum uniflorum (L.) DC inflorescence ameliorate LPS-mediated acute lung injury by alleviating inflammatory responses via the Nrf2/HO-1 signaling pathway.

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Journal of ethnopharmacology 2022 Oct 5;296:115497

Realgar-induced nephrotoxicity via ferroptosis in mice.

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DHA-Enriched Phospholipids and EPA-Enriched Phospholipids Alleviate Lipopolysaccharide-Induced Intestinal Barrier Injury in Mice via a Sirtuin 1-Dependent Mechanism.

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Journal of agricultural and food chemistry 2022 Mar 9;70(9):2911-2922

Fucoxanthin Attenuates Free Fatty Acid-Induced Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism/Oxidative Stress/Inflammation via the AMPK/Nrf2/TLR4 Signaling Pathway.

Ye J, Zheng J, Tian X, Xu B, Yuan F, Wang B, Yang Z, Huang F
Marine drugs 2022 Mar 25;20(4)

Endogenous hydrogen sulfide counteracts polystyrene nanoplastics-induced mitochondrial apoptosis and excessive autophagy via regulating Nrf2 and PGC-1α signaling pathway in mouse spermatocyte-derived GC-2spd(ts) cells.

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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jun;164:113071

Apple Polyphenols Improve Intestinal Antioxidant Capacity and Barrier Function by Activating the Nrf2/Keap1 Signaling Pathway in a Pig Model.

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Journal of agricultural and food chemistry 2022 Jun 22;70(24):7576-7585

Procyanidins inhibit zearalenone-induced apoptosis and oxidative stress of porcine testis cells through activation of Nrf2 signaling pathway.

Yan R, Wang H, Zhu J, Wang T, Nepovimova E, Long M, Li P, Kuca K, Wu W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2022 Jul;165:113061

Perilipin 5 protects against oxygen-glucose deprivation/reoxygenation-elicited neuronal damage by inhibiting oxidative stress and inflammatory injury via the Akt-GSK-3β-Nrf2 pathway.

Huo K, Ma KG, Guo QY, Duan P, Xu J
International immunopharmacology 2022 Jul;108:108718

Salvianolate ameliorates renal tubular injury through the Keap1/Nrf2/ARE pathway in mouse kidney ischemia-reperfusion injury.

Sun D, Cui S, Ma H, Zhu P, Li N, Zhang X, Zhang L, Xuan L, Li J
Journal of ethnopharmacology 2022 Jul 15;293:115331

Mesenchymal stem cells-derived small extracellular vesicles alleviate diabetic retinopathy by delivering NEDD4.

Sun F, Sun Y, Zhu J, Wang X, Ji C, Zhang J, Chen S, Yu Y, Xu W, Qian H
Stem cell research & therapy 2022 Jul 15;13(1):293

Effect of dietary L-theanine supplementation on skeletal muscle fiber type transformation in vivo.

Chen X, Zhang M, Xue Y, Liang D, An W, Jia G, Zhao H, Liu G, Huang Z
The Journal of nutritional biochemistry 2022 Jan;99:108859

Apple polyphenols improve intestinal barrier function by enhancing antioxidant capacity and suppressing inflammation in weaning piglets.

Guo Z, Chen X, Huang Z, Chen D, Yu J, Yan H, Chen H, He J, Zheng P, Luo Y, Yu B
Animal science journal = Nihon chikusan Gakkaiho 2022 Jan-Dec;93(1):e13747

Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.

Li JW, Wang RL, Xu J, Sun KY, Jiang HM, Sun ZY, Lv ZY, Xu XQ, Wu R, Guo H, Jiang Q, Shi DQ
Acta pharmacologica Sinica 2022 Feb;43(2):417-428

Synthesis of lathyrane diterpenoid nitrogen-containing heterocyclic derivatives and evaluation of their anti-inflammatory activities.

Wang W, Xiong L, Li Y, Song Z, Sun D, Li H, Chen L
Bioorganic & medicinal chemistry 2022 Feb 15;56:116627

Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice.

Ni L, Xiao J, Zhang D, Shao Z, Huang C, Wang S, Wu Y, Tian N, Sun L, Wu A, Zhou Y, Wang X, Zhang X
Cell death & disease 2022 Feb 10;13(2):140

Dietary L-theanine supplementation improves lipid metabolism and antioxidant capacity in weaning piglets.

Chen X, Chen L, Qin Y, Mao Z, Huang Z, Jia G, Zhao H, Liu G
Animal biotechnology 2022 Dec;33(7):1407-1415

Effect of dietary L-theanine supplementation on skeletal muscle fiber type transformation in weaning piglets.

Chen X, Chen L, Qin Y, Mao Z, Jia G, Zhao H, Liu G, Huang Z
Animal biotechnology 2022 Dec;33(7):1389-1397

Daidzein supplementation improved fecundity in sows via modulation of ovarian oxidative stress and inflammation.

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The Journal of nutritional biochemistry 2022 Dec;110:109145

Elsholtzia bodinieri Vaniot Ameliorated Acute Lung Injury by NQO1, BCL2 and PTGS2 In Silico and In Vitro Analyses.

Sun J, Jiang X, Chen Y, Guo S, Zhao Z, Cao J, Liu Y, Cheng G, Li Y, Tian L
International journal of molecular sciences 2022 Dec 9;23(24)

Monkfish (Lophius litulon) Peptides Ameliorate High-Fat-Diet-Induced Nephrotoxicity by Reducing Oxidative Stress and Inflammation via Regulation of Intestinal Flora.

Ren X, Miao B, Cao H, Tian X, Shen L, Yang Z, Yuan F, Ding Y
Molecules (Basel, Switzerland) 2022 Dec 28;28(1)

Targeting PCSK9 in Liver Cancer Cells Triggers Metabolic Exhaustion and Cell Death by Ferroptosis.

Alannan M, Fatrouni H, Trézéguet V, Dittrich-Domergue F, Moreau P, Siegfried G, Liet B, Khatib AM, Grosset CF, Badran B, Fayyad-Kazan H, Merched AJ
Cells 2022 Dec 23;12(1)

Protective Effects of Atractylodis lancea Rhizoma on Lipopolysaccharide-Induced Acute Lung Injury via TLR4/NF-κB and Keap1/Nrf2 Signaling Pathways In Vitro and In Vivo.

Shi K, Xiao Y, Dong Y, Wang D, Xie Y, Tu J, Xu K, Zhou Z, Cao G, Liu Y
International journal of molecular sciences 2022 Dec 17;23(24)

Dual antioxidant activity and the related mechanisms of a novel pentapeptide GLP4 from the fermented mycelia of Ganoderma lingzhi.

Huang P, Luo FJ, Ma YC, Wang SX, Huang J, Qin DD, Xue FF, Liu BY, Wu Q, Wang XL, Liu GQ
Food & function 2022 Aug 30;13(17):9032-9048

Evaluation of HZX-960, a novel DCN1-UBC12 interaction inhibitor, as a potential antifibrotic compound for liver fibrosis.

Zhou W, Dong G, Gao G, He Z, Xu J, Aziz S, Ma L, Zhao W
Biochemistry and cell biology = Biochimie et biologie cellulaire 2022 Aug 1;100(4):309-324

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Chen X, Wang Y, Chen D, Yu B, Huang Z
Animal biotechnology 2022 Apr;33(2):356-361

Sevoflurane preconditioning prevents acute renal injury caused by ischemia-reperfusion in mice via activation of the Nrf2 signaling pathway.

Wang WX, Zhao ZR, Bai Y, Li YX, Gao XN, Zhang S, Sun YB
Experimental and therapeutic medicine 2022 Apr;23(4):303

Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.

Ni L, Lin Z, Hu S, Shi Y, Jiang Z, Zhao J, Zhou Y, Wu Y, Tian N, Sun L, Wu A, Pan Z, Zhang X, Wang X
Biochemical pharmacology 2022 Apr;198:114935

Novel oral edaravone attenuates diastolic dysfunction of diabetic cardiomyopathy by activating the Nrf2 signaling pathway.

Wang L, Zeng YQ, Gu JH, Song R, Cang PH, Xu YX, Shao XX, Pu LJ, Luo HY, Zhou XF
European journal of pharmacology 2022 Apr 5;920:174846

Dihydromyricetin Enhances Intestinal Antioxidant Capacity of Growing-Finishing Pigs by Activating ERK/Nrf2/HO-1 Signaling Pathway.

Wei C, Chen X, Chen D, Yu B, Zheng P, He J, Chen H, Yan H, Luo Y, Huang Z
Antioxidants (Basel, Switzerland) 2022 Apr 2;11(4)

Loss of serine/threonine protein kinase 25 in retinal ganglion cells ameliorates high glucose-elicited damage through regulation of the AKT-GSK-3β/Nrf2 pathway.

Zhou Z, Li H, Bai S, Xu Z, Jiao Y
Biochemical and biophysical research communications 2022 Apr 16;600:87-93

Farrerol Enhances Nrf2-Mediated Defense Mechanisms against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial Cells by Activating Akt and MAPK.

Ma N, Yang X, Qi C, Yu Q, Zhu C, Ren H
Oxidative medicine and cellular longevity 2021;2021:8847844

Limonin Inhibits IL-1β-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2.

Jin J, Lv X, Wang B, Ren C, Jiang J, Chen H, Chen X, Gu M, Pan Z, Tian N, Wu A, Sun L, Gao W, Wang X, Zhang X, Wu Y, Zhou Y
Oxidative medicine and cellular longevity 2021;2021:7292512

MCC950, the NLRP3 Inhibitor, Protects against Cartilage Degradation in a Mouse Model of Osteoarthritis.

Ni B, Pei W, Qu Y, Zhang R, Chu X, Wang Y, Huang X, You H
Oxidative medicine and cellular longevity 2021;2021:4139048

Bioactive Peptide F2d Isolated from Rice Residue Exerts Antioxidant Effects via Nrf2 Signaling Pathway.

Liu J, Wu Q, Yang T, Yang F, Guo T, Zhou Y, Han S, Luo Y, Guo T, Luo F, Lin Q
Oxidative medicine and cellular longevity 2021;2021:2637577

Round Scad-Derived Octapeptide WCPFSRSF Confers Neuroprotection by Regulating Akt/Nrf2/NFκB Signaling.

Zhang Q, Su G, Yang Q, Wei Z, Wang J, Zheng L, Zhao M
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10606-10616

Protective Effects and Mechanisms of Procyanidins on Parkinson's Disease In Vivo and In Vitro.

Chen J, Chen Y, Zheng Y, Zhao J, Yu H, Zhu J, Li D
Molecules (Basel, Switzerland) 2021 Sep 13;26(18)

A new ferroptosis inhibitor, isolated from Ajuga nipponensis, protects neuronal cells via activating NRF2-antioxidant response elements (AREs) pathway.

Tan Q, Fang Y, Peng X, Zhou H, Xu J, Gu Q
Bioorganic chemistry 2021 Oct;115:105177

Cyanidin-3-O-glucoside and its metabolite protocatechuic acid ameliorate 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induced cytotoxicity in HepG2 cells by regulating apoptotic and Nrf2/p62 pathways.

Zhao L, Zhou N, Zhang H, Pan F, Ai X, Wang Y, Hao S, Wang C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112582

miR-98-5p protects against cerebral ischemia/reperfusion injury through anti-apoptosis and anti-oxidative stress in mice.

Yu S, Zhai J, Yu J, Yang Q, Yang J
Journal of biochemistry 2021 Mar 5;169(2):195-206

Alpinetin exerts anti-inflammatory, anti-oxidative and anti-angiogenic effects through activating the Nrf2 pathway and inhibiting NLRP3 pathway in carbon tetrachloride-induced liver fibrosis.

Zhu Z, Hu R, Li J, Xing X, Chen J, Zhou Q, Sun J
International immunopharmacology 2021 Jul;96:107660

Proteomics analysis in the kidney of mice following oral feeding Realgar.

Zhang S, Li C, Feng T, Cao S, Zhou H, Li L, Hu Q, Mao X, Ji S
Journal of ethnopharmacology 2021 Jul 15;275:114118

Antioxidant properties of red raspberry extract alleviate hepatic fibrosis via inducing apoptosis and transdifferentiation of activated hepatic stellate cells.

Wu TH, Wang PW, Lin TY, Yang PM, Li WT, Yeh CT, Pan TL
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Dec;144:112284

Dietary dihydromyricetin supplementation enhances antioxidant capacity and improves lipid metabolism in finishing pigs.

Guo Z, Chen X, Huang Z, Chen D, Yu B, Chen H, Yu J, Yan H, Zheng P, Luo Y
Food & function 2021 Aug 2;12(15):6925-6935

Limonin induces apoptosis of HL-60 cells by inhibiting NQO1 activity.

Chen Y, Liang J, Liang X, Chen J, Wang Y, Cao J, Sun C, Ye J, Chen Q
Food science & nutrition 2021 Apr;9(4):1860-1869

Ursodeoxycholic Acid Protects Against Arsenic Induced Hepatotoxicity by the Nrf2 Signaling Pathway.

Li C, Zhang S, Li L, Hu Q, Ji S
Frontiers in pharmacology 2020;11:594496

Role of CYP4F2 as a novel biomarker regulating malignant phenotypes of liver cancer cells via the Nrf2 signaling axis.

Wan S, Pan Q, Yang G, Kuang J, Luo S
Oncology letters 2020 Oct;20(4):13

Crocin ameliorates arsenic trioxide‑induced cardiotoxicity via Keap1-Nrf2/HO-1 pathway: Reducing oxidative stress, inflammation, and apoptosis.

Liang Y, Zheng B, Li J, Shi J, Chu L, Han X, Chu X, Zhang X, Zhang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110713

Dietary Ferulic Acid Supplementation Improves Antioxidant Capacity and Lipid Metabolism in Weaned Piglets.

Wang Y, Chen X, Huang Z, Chen D, Yu B, Yu J, Chen H, He J, Luo Y, Zheng P
Nutrients 2020 Dec 12;12(12)

Induction of Nrf2 pathway by Dendrobium nobile Lindl. alkaloids protects against carbon tetrachloride induced acute liver injury.

Li S, Zhou J, Xu S, Li J, Liu J, Lu Y, Shi J, Zhou S, Wu Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109073

CZ-7, a new derivative of Claulansine F, ameliorates 2VO-induced vascular dementia in rats through a Nrf2-mediated antioxidant responses.

Liu DD, Yuan X, Chu SF, Chen C, Ren Q, Luo P, Lin MY, Wang SS, Zhu TB, Ai QD, Zang YD, Zhang DM, He X, Huang ZH, Sun HS, Feng ZP, Chen NH
Acta pharmacologica Sinica 2019 Apr;40(4):425-440

Procyanidin B2 mitigates behavioral impairment and protects myelin integrity in cuprizone-induced schizophrenia in mice.

Tian H, Sun W, Zhang Q, Li X, Sang Y, Li J, Niu Y, Ding H
RSC advances 2018 Jun 27;8(42):23835-23846

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