TCEA2

The protein encoded by this gene is found in the nucleus, where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. The encoded protein has been shown to interact with general transcription factor IIB, a basal transcription factor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Description

Transcription elongation factor A2

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Centrosome

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

20 (64049836 - 64072347)

Ensembl ID

ENSG00000171703  (ver. 103.38)

Orthologs

Mouse Tcea2: ENSMUSG00000059540

UniProt

Q15560

neXtProt

NX_Q15560

Human splice variants
Mouse splice variants

Protein structure