APR04114G

antibody from Leading Biology

Targeting: PLEKHF1 APPD, MGC4090, PHAFIN1, ZFYVE15

Western blot (Recommended by provider)

Antibody Data

Product number

APR04114G

Provider

Leading Biology

Product name

PLEKHF1 Antibody (N-term)

Antibody type

Polyclonal

Description

PLEKHF1 may induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.