10-7564

antibody from ABEOMICS Inc.

Targeting: FLT1 FLT, VEGFR1

Antibody data

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Validation data

Product number: 10-7564 - Provider product page
Provider: ABEOMICS Inc.
Product name: Anti-FLT1 Antibody
Antibody type: Monoclonal
Description: FLT-1 (fms-related tyrosine kinase 1) is an endogenous inhibitor of vascular endothelial growth factor, which is involved in cardiovascular remodeling and atherosclerosis development. It potently inhibits angiogenesis by binding extracellularly to VEGF (vascular endothelial growth factor). FLT-1 is expressed on tumor cells and is implicated in tumor growth and progression. It is overexpressed in primary tumors and nodal metastasis. FLT-1 regulates monocyte migration, recruits endothelial cell progenitors, increases the adhesive properties of natural killer cells and induces growth factors. It is observed in many diseases with endothelial dysfunction, including pre-eclampsia and diabetic retinopathy, but whether it contributes to endothelial injury in IgAN requires further exploration.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: A partial length recombinant FLT1 p rotein (amino acids 102-321) was us ed as the immunogen for this antibo dy.
Isotype: IgG
Antibody clone number: ABM4A56
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing

FLT1 protein structure - 10-7564 shown in red.