Antibody data
- Antibody Data
- Antigen structure
- References [339]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 14695-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14695-1-AP, RRID:AB_2082037
- Product name
- Collagen Type I antibody
- Antibody type
- Polyclonal
- Description
- Collagen Type I antibody (Cat. #14695-1-AP) is a rabbit polyclonal antibody that shows reactivity with mouse, human, pig, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The DR1‑CSE/H(2)S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice.
Morphological changes of macrophages and their potential contribution to tendon healing.
Berberine ameliorates erectile dysfunction in rats with streptozotocin-induced diabetes mellitus through the attenuation of apoptosis by inhibiting the SPHK1/S1P/S1PR2 and MAPK pathways.
Necroptosis in pulmonary macrophages promotes silica-induced inflammation and interstitial fibrosis in mice.
Epigenetic Repression of Chloride Channel Accessory 2 Transcription in Cardiac Fibroblast: Implication in Cardiac Fibrosis.
Amlexanox and Forskolin Prevents Isoproterenol-Induced Cardiomyopathy by Subduing Cardiomyocyte Hypertrophy and Maladaptive Inflammatory Responses.
Estrogen Protects Vasomotor Functions in Rats During Catecholamine Stress.
Early Passive Leg Movement Prevents Against the Development of Heart Failure With Preserved Ejection Fraction in Rats.
In Vitro Methods to Evaluate the Effects of Mesenchymal Stem Cells on TGF-β1-Induced Pulmonary Fibrosis.
Nobiletin Attenuates Pathological Cardiac Remodeling after Myocardial Infarction via Activating PPARγ and PGC1α.
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
Puerarin Alleviates UUO-Induced Inflammation and Fibrosis by Regulating the NF-κB P65/STAT3 and TGFβ1/Smads Signaling Pathways.
Pressing Intervention Promotes the Skeletal Muscle Repair of Traumatic Myofascial Trigger Points in Rats.
Substance P-induced RAD16-I scaffold mediated hUCMSCs stereo-culture triggers production of mineralized nodules and collagen-like fibers by promoting osteogenic genes expression.
Deletion of p16 accelerates fracture healing in geriatric mice.
Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis Partly by Inhibiting the Expression of LOX and LOXL-2.
Comprehensive Bioinformatics Analysis Identifies POLR2I as a Key Gene in the Pathogenesis of Hypertensive Nephropathy.
LncRNA Nuclear-Enriched Abundant Transcript 1 Regulates Atrial Fibrosis via the miR-320/NPAS2 Axis in Atrial Fibrillation.
Activation of the Cholinergic Anti-inflammatory Pathway Attenuated Angiotension II-Dependent Hypertension and Renal Injury.
Use of Platelet-Rich Plasma Plus Suramin, an Antifibrotic Agent, to Improve Muscle Healing After Injuries.
Identifying miRNA modules associated with progression of keloids through weighted gene co-expression network analysis and experimental validation in vitro.
Traditional Chinese medicine Yiqi Huoxue recipe attenuates hepatic fibrosis via YAP/TAZ signaling.
Exercise training ameliorates early diabetic kidney injury by regulating the H2 S/SIRT1/p53 pathway.
IGF-1-Expressing Placenta-Derived Mesenchymal Stem Cells Promote Scalding Wound Healing.
Hydrogen gas inhalation ameliorates cardiac remodelling and fibrosis by regulating NLRP3 inflammasome in myocardial infarction rats.
The different functions of short and long thymic stromal lymphopoietin isoforms in autophagy-mediated asthmatic airway inflammation and remodeling.
Penetration Cascade of Size Switchable Nanosystem in Desmoplastic Stroma for Improved Pancreatic Cancer Therapy.
Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload.
Effects of andrographolide on renal tubulointersticial injury and fibrosis. Evidence of its mechanism of action.
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Heat-killed Propionibacterium acnes augment the protective effect of 28-kDa glutathione S-transferases antigen against Schistosoma mansoni infection.
Patterned vascularization in a directional ice-templated scaffold of decellularized matrix.
METTL3 improves cardiomyocyte proliferation upon myocardial infarction via upregulating miR-17-3p in a DGCR8-dependent manner.
Ginsenoside Rg1 attenuates mechanical stress-induced cardiac injury via calcium sensing receptor-related pathway.
Identification of YAP1 as a novel downstream effector of the FGF2/STAT3 pathway in the pathogenesis of renal tubulointerstitial fibrosis.
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Injectable self-assembling peptide nanofiber hydrogel as a bioactive 3D platform to promote chronic wound tissue regeneration.
N6-methyladenosine modification of CDH1 mRNA promotes PM2.5-induced pulmonary fibrosis via mediating epithelial mesenchymal transition.
Exosomal MicroRNA-21 Promotes Keloid Fibroblast Proliferation and Collagen Production by Inhibiting Smad7.
Improved epicardial cardiac fibroblast generation from iPSCs.
Protection of CAPE-pNO2 Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
MyD88 in Macrophages Enhances Liver Fibrosis by Activation of NLRP3 Inflammasome in HSCs.
Lipoxin A4 inhibits ovalbumin-induced airway inflammation and airway remodeling in a mouse model of asthma.
Macrophage-derived exosomes mediate silica-induced pulmonary fibrosis by activating fibroblast in an endoplasmic reticulum stress-dependent manner.
MiR-155 promotes colitis-associated intestinal fibrosis by targeting HBP1/Wnt/β-catenin signalling pathway.
Fluorofenidone inhibits epithelial-mesenchymal transition in human lens epithelial cell line FHL 124: a promising therapeutic strategy against posterior capsular opacification.
Splicing factor SRSF6 mediates pleural fibrosis.
Adiponectin Alleviates Intestinal Fibrosis by Enhancing AMP-Activated Protein Kinase Phosphorylation.
Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy.
Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways.
ADAMTS13 inhibits oxidative stress and ameliorates progressive chronic kidney disease following ischaemia/reperfusion injury.
Umbilical cord-derived mesenchymal stem cells exert anti-fibrotic action on hypertrophic scar-derived fibroblasts in co-culture by inhibiting the activation of the TGF β1/Smad3 pathway.
Aptamer-SH2 superbinder-based targeted therapy for pancreatic ductal adenocarcinoma.
SAIL: a new conserved anti-fibrotic lncRNA in the heart.
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Concentrated exosomes from menstrual blood-derived stromal cells improves ovarian activity in a rat model of premature ovarian insufficiency.
WISP-1 induced by mechanical stress contributes to fibrosis and hypertrophy of the ligamentum flavum through Hedgehog-Gli1 signaling.
HIF-1α is necessary for activation and tumour-promotion effect of cancer-associated fibroblasts in lung cancer.
Role and mechanism of TXNIP in ageing-related renal fibrosis.
Pre-emptive pharmacological inhibition of fatty acid-binding protein 4 attenuates kidney fibrosis by reprogramming tubular lipid metabolism.
Comparison of chondrogenesis-related biological behaviors between human urine-derived stem cells and human bone marrow mesenchymal stem cells from the same individual.
Mesenchymal stem cells ameliorate silica-induced pulmonary fibrosis by inhibition of inflammation and epithelial-mesenchymal transition.
Nrf2 activation is involved in osteogenic differentiation of periodontal ligament stem cells under cyclic mechanical stretch.
Vincristine attenuates cardiac fibrosis through the inhibition of NLRP3 inflammasome activation.
Chloride channel accessory 1 integrates chloride channel activity and mTORC1 in aging-related kidney injury.
Periplocymarin protects against myocardial fibrosis induced by β-adrenergic activation in mice.
C188-9 reduces TGF-β1-induced fibroblast activation and alleviates ISO-induced cardiac fibrosis in mice.
Dopamine D1 receptor alleviates doxorubicin-induced cardiac injury by inhibiting NLRP3 inflammasome.
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.
Huoxin Pill inhibits isoproterenol-induced transdifferentiation and collagen synthesis in cardiac fibroblasts through the TGF-β/Smads pathway.
SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation.
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Effect of human umbilical cord-derived mesenchymal stem cells on murine model of bronchiolitis obliterans like injury.
Tormentic acid inhibits hepatic stellate cells activation via blocking PI3K/Akt/mTOR and NF-κB signalling pathways.
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway.
Citrate regulates extracellular matrix mineralization during osteoblast differentiation in vitro.
Naringin attenuates renal interstitial fibrosis by regulating the TGF-β/Smad signaling pathway and inflammation.
Responsive and activable nanomedicines for remodeling the tumor microenvironment.
Paroxetine Attenuates Cardiac Hypertrophy Via Blocking GRK2 and ADRB1 Interaction in Hypertension.
Bortezomib limits renal allograft interstitial fibrosis by inhibiting NF-κB/TNF-α/Akt/mTOR/P70S6K/Smurf2 pathway via IκBα protein stabilization.
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Silencing of METTL3 attenuates cardiac fibrosis induced by myocardial infarction via inhibiting the activation of cardiac fibroblasts.
FoxM1 promotes Wnt/β-catenin pathway activation and renal fibrosis via transcriptionally regulating multi-Wnts expressions.
Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice.
Proximal tubular epithelial insulin receptor mediates high-fat diet-induced kidney injury.
Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats.
Leonurine Attenuates Myocardial Fibrosis Through Upregulation of miR-29a-3p in Mice Post-myocardial Infarction.
Ginsenoside Rb1 attenuates age-associated vascular impairment by modulating the Gas6 pathway.
Epigallocatechin gallate (EGCG) attenuates myocardial hypertrophy and fibrosis induced by transverse aortic constriction via inhibiting the Akt/mTOR pathway.
Adipose-derived mesenchymal stem cell exosomes inhibit transforming growth factor-β1-induced collagen synthesis in oral mucosal fibroblasts.
Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.
MicroRNA-210-5p alleviates cardiac fibrosis via targeting transforming growth factor-beta type I receptor in rats on high sodium chloride (NaCl)-based diet.
The application of human periodontal ligament stem cells and biomimetic silk scaffold for in situ tendon regeneration.
Deficiency of CARMA3 attenuates the development of bleomycin induced pulmonary fibrosis.
A suitable silicosis mouse model was constructed by repeated inhalation of silica dust via nose.
Enzymatically crosslinked silk-nanosilicate reinforced hydrogel with dual-lineage bioactivity for osteochondral tissue engineering.
Protein tyrosine phosphatase 1B regulates fibroblasts proliferation, motility and extracellular matrix synthesis via the MAPK/ERK signalling pathway in keloid.
Nintedanib downregulates the transition of cultured systemic sclerosis fibrocytes into myofibroblasts and their pro-fibrotic activity.
ER-anchored CRTH2 antagonizes collagen biosynthesis and organ fibrosis via binding LARP6.
Inhibition of DNA methylation de-represses peroxisome proliferator-activated receptor-γ and attenuates pulmonary fibrosis.
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
Adenosine A3 receptor activated in H2O2 oxidative stress of primary open-angle glaucoma.
Matrine attenuates pathological cardiac fibrosis via RPS5/p38 in mice.
Overexpression of Fgf8 in the epidermis inhibits hair follicle development.
HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.
The Antiproliferative and Antifibrotic Effects of Cisplatin on Primary Human Vocal Fold Fibroblasts.
CDKN2a/p16 Antagonizes Hepatic Stellate Cell Activation and Liver Fibrosis by Modulating ROS Levels.
Ginsenoside Rb1 Ameliorates Age-Related Myocardial Dysfunction by Regulating the NF-[Formula: see text]B Signaling Pathway.
Protective Effects of MitoTEMPO on Nonalcoholic Fatty Liver Disease via Regulating Myeloid-Derived Suppressor Cells and Inflammation in Mice.
Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway.
Exposure to Air Pollution Exacerbates Inflammation in Rats with Preexisting COPD.
Withaferin A Exerts Preventive Effect on Liver Fibrosis through Oxidative Stress Inhibition in a Sirtuin 3-Dependent Manner.
miR-876 Inhibits EMT and Liver Fibrosis via POSTN to Suppress Metastasis in Hepatocellular Carcinoma.
Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line.
Resveratrol promotes osteoblastic differentiation in a rat model of postmenopausal osteoporosis by regulating autophagy.
Galectin-3 Induces Atrial Fibrosis by Activating the TGF-β1/Smad Pathway in Patients with Atrial Fibrillation.
Inactivation of Pancreatic Stellate Cells by Exendin-4 Inhibits the Migration and Invasion of Pancreatic Cancer Cells.
Dexmedetomidine Exerted Anti-arrhythmic Effects in Rat With Ischemic Cardiomyopathy via Upregulation of Connexin 43 and Reduction of Fibrosis and Inflammation.
Aerosolized Thyroid Hormone Prevents Radiation Induced Lung Fibrosis.
Selective targeting of ubiquitination and degradation of PARP1 by E3 ubiquitin ligase WWP2 regulates isoproterenol-induced cardiac remodeling.
miR-26a attenuates cardiac apoptosis and fibrosis by targeting ataxia-telangiectasia mutated in myocardial infarction.
LncRNA TRPC7-AS1 regulates nucleus pulposus cellular senescence and ECM synthesis via competing with HPN for miR-4769-5p binding.
hUMSCs regulate the differentiation of ovarian stromal cells via TGF-β1/Smad3 signaling pathway to inhibit ovarian fibrosis to repair ovarian function in POI rats.
Inhibition of p66Shc Oxidative Signaling via CA-Induced Upregulation of miR-203a-3p Alleviates Liver Fibrosis Progression.
Polystyrene microplastics cause cardiac fibrosis by activating Wnt/β-catenin signaling pathway and promoting cardiomyocyte apoptosis in rats.
MSC-derived exosomes protect against oxidative stress-induced skin injury via adaptive regulation of the NRF2 defense system.
Endothelin receptors promote schistosomiasis-induced hepatic fibrosis via splenic B cells.
Si-Miao-Yong-An Decoction attenuates isoprenaline-induced myocardial fibrosis in AMPK-driven Akt/mTOR and TGF-β/SMAD3 pathways.
TGFβ acts through PDGFRβ to activate mTORC1 via the Akt/PRAS40 axis and causes glomerular mesangial cell hypertrophy and matrix protein expression.
MAD2B contributes to parietal epithelial cell activation and crescentic glomerulonephritis via Skp2.
Citri Reticulatae Pericarpium protects against isoproterenol-induced chronic heart failure via activation of PPARγ.
Crosstalk between pleural mesothelial cell and lung fibroblast contributes to pulmonary fibrosis.
Magnesium Calcium Phosphate Cement Incorporating Citrate for Vascularized Bone Regeneration.
Involvement of FATP2-mediated tubular lipid metabolic reprogramming in renal fibrogenesis.
Caveolin-1 stabilizes ATP7A, a copper transporter for extracellular SOD, in vascular tissue to maintain endothelial function.
TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.
Melatonin up-regulates bone marrow mesenchymal stem cells osteogenic action but suppresses their mediated osteoclastogenesis via MT2 -inactivated NF-κB pathway.
Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models.
Comprehensive circRNA expression profile and construction of circRNA-related ceRNA network in cardiac fibrosis.
Lactoferrin Contributes a Renoprotective Effect in Acute Kidney Injury and Early Renal Fibrosis.
HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis.
G protein-coupled receptor kinase-2: A potential biomarker for early diabetic cardiomyopathy.
Local SDF-1α application enhances the therapeutic efficacy of BMSCs transplantation in osteoporotic bone healing.
Epithelial-mesenchymal transition and metastasis of colon cancer cells induced by the FAK pathway in cancer-associated fibroblasts.
Meprin-α (Mep1A) enhances TNF-α secretion by mast cells and aggravates abdominal aortic aneurysms.
LncRNA SNHG7 promotes cardiac remodeling by upregulating ROCK1 via sponging miR-34-5p.
High expression of AMAP1, an ARF6 effector, is associated with elevated levels of PD-L1 and fibrosis of pancreatic cancer.
Administration of a mixture of triterpenoids from yeyachun and phenolic acids from danshen ameliorates carbon tetrachloride-induced liver fibrosis in mice by the regulation of intestinal flora.
Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression.
Design, synthesis and discovery of 2(1H)-quinolone derivatives for the treatment of pulmonary fibrosis through inhibition of TGF-β/smad dependent and independent pathway.
Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.
Left Atrial Appendage Fibrosis and 3-Year Clinical Outcomes in Atrial Fibrillation After Endoscopic Ablation: A Histologic Analysis.
The Effect of Mitomycin C on Reducing Endometrial Fibrosis for Intrauterine Adhesion.
Fibroblasts Derived From Human Adipose Stem Cells Produce More Effective Extracellular Matrix and Migrate Faster Compared to Primary Dermal Fibroblasts.
Synthesis and discovery of new compounds bearing coumarin scaffold for the treatment of pulmonary fibrosis.
Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis.
Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury.
Interaction of calcium binding protein S100A16 with myosin-9 promotes cytoskeleton reorganization in renal tubulointerstitial fibrosis.
Suppression of p66Shc prevents hyperandrogenism-induced ovarian oxidative stress and fibrosis.
An all-silk-derived functional nanosphere matrix for sequential biomolecule delivery and in situ osteochondral regeneration.
Apremilast interferes with the TGFβ1-induced transition of human skin fibroblasts into profibrotic myofibroblasts: in vitro study.
LncRNA Gm16410 regulates PM2.5-induced lung Endothelial-Mesenchymal Transition via the TGF-β1/Smad3/p-Smad3 pathway.
Bioactive multi-engineered hydrogel offers simultaneous promise against antibiotic resistance and wound damage.
Morroniside attenuates high glucose-induced BMSC dysfunction by regulating the Glo1/AGE/RAGE axis.
Atorvastatin attenuates TGF‑β1‑induced fibrogenesis by inhibiting Smad3 and MAPK signaling in human ventricular fibroblasts.
Biomineralizaion of hydroxyapatite on polyethylene terephthalate artificial ligaments promotes graft-bone healing after anterior cruciate ligament reconstruction: An in vitro and in vivo study.
Astaxanthin attenuates hepatic damage and mitochondrial dysfunction in non-alcoholic fatty liver disease by up-regulating the FGF21/PGC-1α pathway.
Bone-Inspired Tube Filling Decellularized Matrix of Toad Cartilage Provided an Osteoinductive Microenvironment for Mesenchymal Stem Cells to Facilitate the Radius Defect Repair of Rabbit.
Isoliquiritigenin inhibits TGF-β1-induced fibrogenesis through activating autophagy via PI3K/AKT/mTOR pathway in MRC-5 cells.
Icotinib Attenuates Monocrotaline-Induced Pulmonary Hypertension by Preventing Pulmonary Arterial Smooth Muscle Cell Dysfunction.
Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.
RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice.
Pharmacologic inhibition of RGD-binding integrins ameliorates fibrosis and improves function following kidney injury.
LncRNA MIAT/miR-133a-3p axis regulates atrial fibrillation and atrial fibrillation-induced myocardial fibrosis.
Downregulation of miR-96 suppresses the profibrogenic functions of cardiac fibroblasts induced by angiotensin II and attenuates atrial fibrosis by upregulating KLF13.
COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence.
Long-term voluntary running prevents the onset of symptomatic Friedreich's ataxia in mice.
Septin4 as an autophagy modulator regulates Angiotensin-II mediated VSMCs proliferation and migration.
Silica particles disorganize the polarization of pulmonary macrophages in mice.
Dysregulation of the Wnt Signaling Pathway and Synovial Stem Cell Dysfunction in Osteoarthritis Development.
Kartogenin hydrolysis product 4-aminobiphenyl distributes to cartilage and mediates cartilage regeneration.
Transplantation of adipose-derived stem cells overexpressing inducible nitric oxide synthase ameliorates diabetes mellitus-induced erectile dysfunction in rats.
Costunolide reduces glycolysis-associated activation of hepatic stellate cells via inhibition of hexokinase-2.
Methane-Rich Saline Counteracts Cholestasis-Induced Liver Damage via Regulating the TLR4/NF-κB/NLRP3 Inflammasome Pathway.
Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways.
Indoxyl Sulfate Induces Renal Fibroblast Activation through a Targetable Heat Shock Protein 90-Dependent Pathway.
A Biomimetic Model for Mineralization of Type-I Collagen Fibrils.
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
Presence and function of stress granules in atrial fibrillation.
A Novel Liposomal S-Propargyl-Cysteine: A Sustained Release of Hydrogen Sulfide Reducing Myocardial Fibrosis via TGF-β1/Smad Pathway.
Dioscin ameliorates peritoneal fibrosis by inhibiting epithelial-to-mesenchymal transition of human peritoneal mesothelial cells via the TLR4/MyD88/NF-κB signaling pathway.
A small molecule inhibitor MCC950 ameliorates kidney injury in diabetic nephropathy by inhibiting NLRP3 inflammasome activation.
Stachydrine Ameliorates Cardiac Fibrosis Through Inhibition of Angiotensin II/Transformation Growth Factor β1 Fibrogenic Axis.
Exogenous angiotensin (1-7) directly inhibits epithelial-mesenchymal transformation induced by transforming growth factor-β1 in alveolar epithelial cells.
lncRNA NR_038323 Suppresses Renal Fibrosis in Diabetic Nephropathy by Targeting the miR-324-3p/DUSP1 Axis.
Germacrane Sesquiterpenoids as a New Type of Anticardiac Fibrosis Agent Targeting Transforming Growth Factor β Type I Receptor.
Pioglitazone attenuates kidney fibrosis via miR-21-5p modulation.
Ghrelin Fights Against Titanium Particle-Induced Inflammatory Osteolysis Through Activation of β-Catenin Signaling Pathway.
The effect of topical ramipril and losartan cream in inhibiting scar formation.
SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition.
Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection.
Role of CCR2 in the Development of Streptozotocin-Treated Diabetic Cardiomyopathy.
Long non-coding RNA TUG1 promotes airway remodelling by suppressing the miR-145-5p/DUSP6 axis in cigarette smoke-induced COPD.
Sapylin (OK-432) alters inflammation and angiogenesis in vivo and vitro.
Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats.
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7.
Diminished membrane recruitment of Akt is instrumental in alcohol-associated osteopenia via the PTEN/Akt/GSK-3β/β-catenin axis.
Toxicity Effects of Methylene Blue on Rat Intervertebral Disc Annulus Fibrosus Cells.
Citric acid enhances the physical properties, cytocompatibility and osteogenesis of magnesium calcium phosphate cement.
Aloe-Emodin Ameliorates Renal Fibrosis Via Inhibiting PI3K/Akt/mTOR Signaling Pathway In Vivo and In Vitro.
miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal cells in rats.
Induction of Fibrosis and Autophagy in Kidney Cells by Vinyl Chloride.
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.
Eliciting α7-nAChR exerts cardioprotective effects on ischemic cardiomyopathy via activation of AMPK signalling.
HBOA ameliorates CCl4-incuded liver fibrosis through inhibiting TGF-β1/Smads, NF-κB and ERK signaling pathways.
LncRNA PFAR contributes to fibrogenesis in lung fibroblasts through competitively binding to miR-15a.
Psoralen attenuates bleomycin-induced pulmonary fibrosis in mice through inhibiting myofibroblast activation and collagen deposition.
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
Role of synovium-derived fibrous cartilage in temporomandibular joint synovial chondromatosis.
Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin.
Gene-targeted deletion in mice of the Ets-1 transcription factor, a candidate gene in the Jacobsen syndrome kidney "critical region," causes abnormal kidney development.
Neutralization of IL-18 by IL-18 binding protein ameliorates bleomycin-induced pulmonary fibrosis via inhibition of epithelial-mesenchymal transition.
Electrophoretic Deposition of Bioadaptive Drug Delivery Coatings on Magnesium Alloy for Bone Repair.
Involvement of serum amyloid A1 in the rupture of fetal membranes through induction of collagen I degradation.
A Novel Tissue-Engineered Corneal Stromal Equivalent Based on Amniotic Membrane and Keratocytes.
Resveratrol Attenuates Pressure Overload-Induced Cardiac Fibrosis and Diastolic Dysfunction via PTEN/AKT/Smad2/3 and NF-κB Signaling Pathways.
Paeonol prevents IL-1β-induced inflammatory response and degradation of type II collagen in human primary chondrocytes.
Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway.
High cholesterol inhibits tendon-related gene expressions in tendon-derived stem cells through reactive oxygen species-activated nuclear factor-κB signaling.
LncRNA PCFL promotes cardiac fibrosis via miR-378/GRB2 pathway following myocardial infarction.
IMM-H007 improves heart function via reducing cardiac fibrosis.
Empagliflozin prevents cardiomyopathy via sGC-cGMP-PKG pathway in type 2 diabetes mice.
Calhex231 Alleviates High Glucose-Induced Myocardial Fibrosis via Inhibiting Itch-Ubiquitin Proteasome Pathway in Vitro.
Liraglutide prevents β-cell apoptosis via inactivation of NOX2 and its related signaling pathway.
Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction.
The inhibitory effects of COL1A2 on colorectal cancer cell proliferation, migration, and invasion.
Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway.
LncRNA PFL contributes to cardiac fibrosis by acting as a competing endogenous RNA of let-7d.
Fibronectin Type III Domain-Containing 5 Attenuates Liver Fibrosis Via Inhibition of Hepatic Stellate Cell Activation.
Annexin A1 is elevated in patients with COPD and affects lung fibroblast function.
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
A novel bioscaffold with naturally-occurring extracellular matrix promotes hepatocyte survival and vessel patency in mouse models of heterologous transplantation.
Interleukin-17 enhances cardiac ventricular remodeling via activating MAPK pathway in ischemic heart failure.
MiR-455-3p suppresses renal fibrosis through repression of ROCK2 expression in diabetic nephropathy.
lncRNA PFAR Promotes Lung Fibroblast Activation and Fibrosis by Targeting miR-138 to Regulate the YAP1-Twist Axis.
Octreotide attenuates hepatic fibrosis and hepatic stellate cells proliferation and activation by inhibiting Wnt/β-catenin signaling pathway, c-Myc and cyclin D1.
lncRNA PFAL promotes lung fibrosis through CTGF by competitively binding miR-18a.
Antifibrotic Agent Pirfenidone Protects against Development of Radiation-Induced Pulmonary Fibrosis in a Murine Model.
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Novel formononetin-7-sal ester ameliorates pulmonary fibrosis via MEF2c signaling pathway.
Emission of sulfur dioxide from polyurethane foam and respiratory health effects.
Thrombin induces protease-activated receptor 1 signaling and activation of human atrial fibroblasts and dabigatran prevents these effects.
Cardioprotection of CAPE-oNO2 against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Autophagic degradation of caveolin-1 promotes liver sinusoidal endothelial cells defenestration.
Notch1 regulates PTEN expression to exacerbate renal tubulointerstitial fibrosis in diabetic nephropathy by inhibiting autophagy via interactions with Hes1.
Interleukin-6 Promotes Proliferation but Inhibits Tenogenic Differentiation via the Janus Kinase/Signal Transducers and Activators of Transcription 3 (JAK/STAT3) Pathway in Tendon-Derived Stem Cells.
Effects of nicotine on the metabolism and gene expression profile of Sprague‑Dawley rat primary osteoblasts.
Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis.
Taurocholic acid is an active promoting factor, not just a biomarker of progression of liver cirrhosis: evidence from a human metabolomic study and in vitro experiments.
β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.
Aucubin Protects against TGFβ1-Induced Cardiac Fibroblasts Activation by Mediating the AMPKα/mTOR Signaling Pathway.
COL1A2 is a Novel Biomarker to Improve Clinical Prediction in Human Gastric Cancer: Integrating Bioinformatics and Meta-Analysis.
Losartan loaded liposomes improve the antitumor efficacy of liposomal paclitaxel modified with pH sensitive peptides by inhibition of collagen in breast cancer.
Regulation of pancreatic stellate cell activation by Notch3.
Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling.
Nicotine Induces Progressive Properties of Lung Adenocarcinoma A549 Cells by Inhibiting Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression and Plasma Membrane Localization.
Crosslinking Enzyme Lysyl Oxidase Modulates Scleral Remodeling in Form-Deprivation Myopia.
Role of Gut-Derived Endotoxin on Type I Collagen Production in the Rat Pancreas After Chronic Alcohol Exposure.
Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis.
Toxoplasma gondii GRA15II effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica.
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis.
Metformin attenuates motility, contraction, and fibrogenic response of hepatic stellate cells in vivo and in vitro by activating AMP-activated protein kinase.
Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway.
Interleukin‑10 promotes proliferation and migration, and inhibits tendon differentiation via the JAK/Stat3 pathway in tendon‑derived stem cells in vitro.
CAPE-pNO2 attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
ClC-3 chloride channels are involved in estradiol regulation of bone formation by MC3T3-E1 osteoblasts.
Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem.
Effect of Polyhydroxybutyrate/Chitosan/Bioglass nanofiber scaffold on proliferation and differentiation of stem cells from human exfoliated deciduous teeth into odontoblast-like cells.
Hydrogen sulfide ameliorates aging-associated changes in the kidney.
Lipopolysaccharide enhances TGF-β1 signalling pathway and rat pancreatic fibrosis.
Inhibition of lysyl oxidase-like 1 (LOXL1) expression arrests liver fibrosis progression in cirrhosis by reducing elastin crosslinking.
Melatonin Protects against Lung Fibrosis by Regulating the Hippo/YAP Pathway.
Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.
The Protective Effect of Cordycepin On Alcohol-Induced Osteonecrosis of the Femoral Head.
Far-infrared suppresses skin photoaging in ultraviolet B-exposed fibroblasts and hairless mice.
Galectin-3 mediates pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension.
High doses of baicalin induces kidney injury and fibrosis through regulating TGF-β/Smad signaling pathway.
MicroRNA-133 overexpression promotes the therapeutic efficacy of mesenchymal stem cells on acute myocardial infarction.
The protective effect of PFTα on alcohol-induced osteonecrosis of the femoral head.
The effects of artocarpin on wound healing: in vitro and in vivo studies.
Bcl-3 is a novel biomarker of renal fibrosis in chronic kidney disease.
Synthesis of the novel PARP-1 inhibitor AG-690/11026014 and its protective effects on angiotensin II-induced mouse cardiac remodeling.
MgAl layered double hydroxide/chitosan porous scaffolds loaded with PFTα to promote bone regeneration.
Cadherin-11 modulates cell morphology and collagen synthesis in periodontal ligament cells under mechanical stress.
Activation of E-prostanoid 3 receptor in macrophages facilitates cardiac healing after myocardial infarction.
Evodiamine attenuates TGF-β1-induced fibroblast activation and endothelial to mesenchymal transition.
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Development of a new biodegradable operative clip made of a magnesium alloy: Evaluation of its safety and tolerability for canine cholecystectomy.
Muscarinic receptor mediated signaling pathways in hepatocytes from CCL4 - induced liver fibrotic rat.
Expression of muscarinic acetylcholine receptors in hepatocytes from rat fibrotic liver.
Ascorbate starvation alters endoplasmic reticulum-resident enzymes in cardiac fibroblasts, priming them for increased procollagen secretion.
Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.
Relaxin alleviates TGFβ1-induced cardiac fibrosis via inhibition of Stat3-dependent autophagy.
Hepatitis B virus X protein promotes the development of liver fibrosis and hepatoma through downregulation of miR-30e targeting P4HA2 mRNA.
Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.
Exogenous H2S modulates mitochondrial fusion-fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state.
Sonodynamic Therapy Inhibits Fibrogenesis in Rat Cardiac Fibroblasts Induced by TGF-β1.
Mixed Aqueous Extract of Salvia Miltiorrhiza Reduces Blood Pressure through Inhibition of Vascular Remodelling and Oxidative Stress in Spontaneously Hypertensive Rats.
Expression of Wnt/β-Catenin Signaling Pathway and Its Regulatory Role in Type I Collagen with TGF-β1 in Scleral Fibroblasts from an Experimentally Induced Myopia Guinea Pig Model.
Tetramethylpyrazine Attenuates Transdifferentiation of TGF-β2-Treated Human Tenon's Fibroblasts.
MAD2B promotes tubular epithelial-to-mesenchymal transition and renal tubulointerstitial fibrosis via Skp2.
Store-Operated Ca2+ Entry (SOCE) contributes to angiotensin II-induced cardiac fibrosis in cardiac fibroblasts.
PPAR-γ is involved in the protective effect of 2,3,4',5-tetrahydroxystilbene-2-O-beta-D-glucoside against cardiac fibrosis in pressure-overloaded rats.
Deletion of interleukin-6 alleviated interstitial fibrosis in streptozotocin-induced diabetic cardiomyopathy of mice through affecting TGFβ1 and miR-29 pathways.
miR-26a suppresses EMT by disrupting the Lin28B/let-7d axis: potential cross-talks among miRNAs in IPF.
Increased expression of Talin1 in the eutopic and ectopic endometria of women with adenomyosis.
A dual strategy to improve the penetration and treatment of breast cancer by combining shrinking nanoparticles with collagen depletion by losartan.
An Ultra-thin Amniotic Membrane as Carrier in Corneal Epithelium Tissue-Engineering.
IL-27 attenuates the TGF-β1-induced proliferation, differentiation and collagen synthesis in lung fibroblasts.
Protective effects of triptolide on TLR4 mediated autoimmune and inflammatory response induced myocardial fibrosis in diabetic cardiomyopathy.
A fundamental study on the dynamics of multiple biomarkers in mouse excisional wounds for wound age estimation.
Ursolic acid attenuates diabetic mesangial cell injury through the up-regulation of autophagy via miRNA-21/PTEN/Akt/mTOR suppression.
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
High Tumor Penetration of Paclitaxel Loaded pH Sensitive Cleavable Liposomes by Depletion of Tumor Collagen I in Breast Cancer.
Establishing principles of macromolecular crowding for in vitro fibrosis research of the vocal fold lamina propria.
High doses of (-)-epigallocatechin-3-gallate from green tea induces cardiac fibrosis in mice.
Identification of genetic loci associated with primary angle-closure glaucoma in the basset hound.
Keratocytes create stromal spaces to promote corneal neovascularization via MMP13 expression.
Surface chemistry modulates osteoblasts sensitivity to low fluid shear stress.
Mechano growth factor E peptide regulates migration and differentiation of bone marrow mesenchymal stem cells.
Surface functionalization of titanium substrates with cecropin B to improve their cytocompatibility and reduce inflammation responses.
Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced cardiac hypertrophy and fibrosis in vivo.
The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2- and Akt-dependent mechanism.
Attenuating effect of Fufang Xueshuantong Capsule on kidney function in diabetic nephropathy model.
Molecular events in matrix protein metabolism in the aging kidney.
Li H, Sun F, Bai S, Chang G, Wu R, Wei Y, Wen X, Xi Y, Hao J, Zaid A
International journal of molecular medicine 2022 Jan;49(1)
International journal of molecular medicine 2022 Jan;49(1)
Morphological changes of macrophages and their potential contribution to tendon healing.
Yang QQ, Zhang L, Zhou YL, Tang JB
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 1):112145
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 1):112145
Berberine ameliorates erectile dysfunction in rats with streptozotocin-induced diabetes mellitus through the attenuation of apoptosis by inhibiting the SPHK1/S1P/S1PR2 and MAPK pathways.
Liu K, Sun T, Luan Y, Chen Y, Song J, Ling L, Yuan P, Li R, Cui K, Ruan Y, Lan R, Wang T, Wang S, Liu J, Rao K
Andrology 2022 Feb;10(2):404-418
Andrology 2022 Feb;10(2):404-418
Necroptosis in pulmonary macrophages promotes silica-induced inflammation and interstitial fibrosis in mice.
Tao H, Zhao H, Ge D, Liao J, Shao L, Mo A, Hu L, Xu K, Wu J, Mu M, Li B, Tao X, Wang J
Toxicology letters 2022 Feb 1;355:150-159
Toxicology letters 2022 Feb 1;355:150-159
Epigenetic Repression of Chloride Channel Accessory 2 Transcription in Cardiac Fibroblast: Implication in Cardiac Fibrosis.
Shao T, Xue Y, Fang M
Frontiers in cell and developmental biology 2021;9:771466
Frontiers in cell and developmental biology 2021;9:771466
Amlexanox and Forskolin Prevents Isoproterenol-Induced Cardiomyopathy by Subduing Cardiomyocyte Hypertrophy and Maladaptive Inflammatory Responses.
Adzika GK, Hou H, Adekunle AO, Rizvi R, Adzraku SY, Li K, Deng QM, Mprah R, Ndzie Noah ML, Adu-Amankwaah J, Machuki JO, Shang W, Ma T, Koda S, Ma X, Sun H
Frontiers in cell and developmental biology 2021;9:719351
Frontiers in cell and developmental biology 2021;9:719351
Estrogen Protects Vasomotor Functions in Rats During Catecholamine Stress.
Zhang L, Li C, Yang L, Adzika GK, Machuki JO, Shi M, Sun Q, Sun H
Frontiers in cardiovascular medicine 2021;8:679240
Frontiers in cardiovascular medicine 2021;8:679240
Early Passive Leg Movement Prevents Against the Development of Heart Failure With Preserved Ejection Fraction in Rats.
Liu J, Ji XX, Fu Y, Zhang WC, Ji HF, Liu JW, Cheng XS, Dong YF
Frontiers in cardiovascular medicine 2021;8:655009
Frontiers in cardiovascular medicine 2021;8:655009
In Vitro Methods to Evaluate the Effects of Mesenchymal Stem Cells on TGF-β1-Induced Pulmonary Fibrosis.
Lan YW, Chen CM, Chong KY
Methods in molecular biology (Clifton, N.J.) 2021;2269:83-92
Methods in molecular biology (Clifton, N.J.) 2021;2269:83-92
Nobiletin Attenuates Pathological Cardiac Remodeling after Myocardial Infarction via Activating PPARγ and PGC1α.
Zhou Y, Yin T, Shi M, Chen M, Wu X, Wang K, Cheang I, Li Y, Shang H, Zhang H, Li X
PPAR research 2021;2021:9947656
PPAR research 2021;2021:9947656
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
Zhang M, Luo C, Lin D, Cui K, Chen Z, Liu J
Oxidative medicine and cellular longevity 2021;2021:8877540
Oxidative medicine and cellular longevity 2021;2021:8877540
Puerarin Alleviates UUO-Induced Inflammation and Fibrosis by Regulating the NF-κB P65/STAT3 and TGFβ1/Smads Signaling Pathways.
Wang J, Ge S, Wang Y, Liu Y, Qiu L, Li J, Huang X, Sun L
Drug design, development and therapy 2021;15:3697-3708
Drug design, development and therapy 2021;15:3697-3708
Pressing Intervention Promotes the Skeletal Muscle Repair of Traumatic Myofascial Trigger Points in Rats.
Jiang Q, Feng X, Liu D, Li T, Kuang X, Liu X, Li W, Li J
Journal of pain research 2021;14:3267-3278
Journal of pain research 2021;14:3267-3278
Substance P-induced RAD16-I scaffold mediated hUCMSCs stereo-culture triggers production of mineralized nodules and collagen-like fibers by promoting osteogenic genes expression.
Li Y, Zhang S, Li W, Zheng X, Xue Y, Hu K, Zhou H
American journal of translational research 2021;13(4):1990-2005
American journal of translational research 2021;13(4):1990-2005
Deletion of p16 accelerates fracture healing in geriatric mice.
Ding Q, Liu H, Liu L, Ma C, Qin H, Wei Y, Ren Y
American journal of translational research 2021;13(10):11107-11125
American journal of translational research 2021;13(10):11107-11125
Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis Partly by Inhibiting the Expression of LOX and LOXL-2.
Tong X, Zhang S, Wang D, Zhang L, Huang J, Zhang T, Fan H
Frontiers in pharmacology 2021;12:709819
Frontiers in pharmacology 2021;12:709819
Comprehensive Bioinformatics Analysis Identifies POLR2I as a Key Gene in the Pathogenesis of Hypertensive Nephropathy.
You S, Xu J, Wu B, Wu S, Zhang Y, Sun Y, Zhang N
Frontiers in genetics 2021;12:698570
Frontiers in genetics 2021;12:698570
LncRNA Nuclear-Enriched Abundant Transcript 1 Regulates Atrial Fibrosis via the miR-320/NPAS2 Axis in Atrial Fibrillation.
Dai H, Zhao N, Liu H, Zheng Y, Zhao L
Frontiers in pharmacology 2021;12:647124
Frontiers in pharmacology 2021;12:647124
Activation of the Cholinergic Anti-inflammatory Pathway Attenuated Angiotension II-Dependent Hypertension and Renal Injury.
Wu SJ, Shi ZW, Wang X, Ren FF, Xie ZY, Lei L, Chen P
Frontiers in pharmacology 2021;12:593682
Frontiers in pharmacology 2021;12:593682
Use of Platelet-Rich Plasma Plus Suramin, an Antifibrotic Agent, to Improve Muscle Healing After Injuries.
Tsai WC, Yu TY, Chang GJ, Chang HN, Lin LP, Lin MS, Pang JS
The American journal of sports medicine 2021 Sep;49(11):3102-3112
The American journal of sports medicine 2021 Sep;49(11):3102-3112
Identifying miRNA modules associated with progression of keloids through weighted gene co-expression network analysis and experimental validation in vitro.
Lv W, Ren Y, Wu M, Luo X, Yu J, Zhang Q, Wu Y
Burns : journal of the International Society for Burn Injuries 2021 Sep;47(6):1359-1372
Burns : journal of the International Society for Burn Injuries 2021 Sep;47(6):1359-1372
Traditional Chinese medicine Yiqi Huoxue recipe attenuates hepatic fibrosis via YAP/TAZ signaling.
Zhao W, Zhang X, Hou M, Zhang Y, Tang Y, Li L, Dong S, Liu L, Zhao D, Li W, Nan Y
Histology and histopathology 2021 Sep;36(9):967-979
Histology and histopathology 2021 Sep;36(9):967-979
Exercise training ameliorates early diabetic kidney injury by regulating the H2 S/SIRT1/p53 pathway.
Yang L, Li DX, Cao BQ, Liu SJ, Xu DH, Zhu XY, Liu YJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Sep;35(9):e21823
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Sep;35(9):e21823
IGF-1-Expressing Placenta-Derived Mesenchymal Stem Cells Promote Scalding Wound Healing.
Cheng S, Lv R, Xu J, Hirman AR, Du L
The Journal of surgical research 2021 Sep;265:100-113
The Journal of surgical research 2021 Sep;265:100-113
Hydrogen gas inhalation ameliorates cardiac remodelling and fibrosis by regulating NLRP3 inflammasome in myocardial infarction rats.
Nie C, Zou R, Pan S, A R, Gao Y, Yang H, Bai J, Xi S, Wang X, Hong X, Yang W
Journal of cellular and molecular medicine 2021 Sep;25(18):8997-9010
Journal of cellular and molecular medicine 2021 Sep;25(18):8997-9010
The different functions of short and long thymic stromal lymphopoietin isoforms in autophagy-mediated asthmatic airway inflammation and remodeling.
Zhao J, Zhang J, Tang S, Wang J, Liu T, Zeng R, Zhu W, Zhang K, Wu J
Immunobiology 2021 Sep;226(5):152124
Immunobiology 2021 Sep;226(5):152124
Penetration Cascade of Size Switchable Nanosystem in Desmoplastic Stroma for Improved Pancreatic Cancer Therapy.
Zhao X, Yang X, Wang X, Zhao X, Zhang Y, Liu S, Anderson GJ, Kim SJ, Li Y, Nie G
ACS nano 2021 Sep 28;15(9):14149-14161
ACS nano 2021 Sep 28;15(9):14149-14161
Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload.
Zou Y, Pan L, Shen Y, Wang X, Huang C, Wang H, Jin X, Yin C, Wang Y, Jia J, Qian J, Zou Y, Gong H, Ge J
Cell death & disease 2021 Sep 25;12(10):877
Cell death & disease 2021 Sep 25;12(10):877
Effects of andrographolide on renal tubulointersticial injury and fibrosis. Evidence of its mechanism of action.
Liu W, Liang L, Zhang Q, Li Y, Yan S, Tang T, Ren Y, Mo J, Liu F, Chen X, Lan T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153650
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153650
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Sun Y, Zhang L, Lu B, Wen J, Wang M, Zhang S, Li Q, Shu F, Lu F, Liu N, Peng S, Zhao Y, Dong S, Lu F, Zhang W, Wang Y
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
Heat-killed Propionibacterium acnes augment the protective effect of 28-kDa glutathione S-transferases antigen against Schistosoma mansoni infection.
Lam HYP, Yang TH, Liang TR, Cheng PC, Chang KC, Peng SY
Acta tropica 2021 Oct;222:106033
Acta tropica 2021 Oct;222:106033
Patterned vascularization in a directional ice-templated scaffold of decellularized matrix.
Shen L, Song X, Xu Y, Tian R, Wang Y, Li P, Li J, Bai H, Zhu H, Wang D
Engineering in life sciences 2021 Oct;21(10):683-692
Engineering in life sciences 2021 Oct;21(10):683-692
METTL3 improves cardiomyocyte proliferation upon myocardial infarction via upregulating miR-17-3p in a DGCR8-dependent manner.
Zhao K, Yang C, Zhang J, Sun W, Zhou B, Kong X, Shi J
Cell death discovery 2021 Oct 13;7(1):291
Cell death discovery 2021 Oct 13;7(1):291
Ginsenoside Rg1 attenuates mechanical stress-induced cardiac injury via calcium sensing receptor-related pathway.
Lu ML, Wang J, Sun Y, Li C, Sun TR, Hou XW, Wang HX
Journal of ginseng research 2021 Nov;45(6):683-694
Journal of ginseng research 2021 Nov;45(6):683-694
Identification of YAP1 as a novel downstream effector of the FGF2/STAT3 pathway in the pathogenesis of renal tubulointerstitial fibrosis.
Li X, Zhang F, Qu L, Xie Y, Ruan Y, Guo Z, Mao Y, Zou Q, Shi M, Xiao Y, Wang Y, Zhou Y, Guo B
Journal of cellular physiology 2021 Nov;236(11):7655-7671
Journal of cellular physiology 2021 Nov;236(11):7655-7671
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Xu Y, Peng W, Han D, Feng F, Wang Z, Gu C, Zhou X, Wu Q
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Injectable self-assembling peptide nanofiber hydrogel as a bioactive 3D platform to promote chronic wound tissue regeneration.
Lou P, Liu S, Wang Y, Pan C, Xu X, Zhao M, Liao G, Yang G, Yuan Y, Li L, Zhang J, Chen Y, Cheng J, Lu Y, Liu J
Acta biomaterialia 2021 Nov;135:100-112
Acta biomaterialia 2021 Nov;135:100-112
N6-methyladenosine modification of CDH1 mRNA promotes PM2.5-induced pulmonary fibrosis via mediating epithelial mesenchymal transition.
Ning J, Du H, Zhang Y, Liu Q, Jiang T, Pang Y, Tian X, Yan L, Niu Y, Zhang R
Toxicological sciences : an official journal of the Society of Toxicology 2021 Nov 4;
Toxicological sciences : an official journal of the Society of Toxicology 2021 Nov 4;
Exosomal MicroRNA-21 Promotes Keloid Fibroblast Proliferation and Collagen Production by Inhibiting Smad7.
Li Q, Fang L, Chen J, Zhou S, Zhou K, Cheng F, Cen Y, Qing Y, Wu J
Journal of burn care & research : official publication of the American Burn Association 2021 Nov 24;42(6):1266-1274
Journal of burn care & research : official publication of the American Burn Association 2021 Nov 24;42(6):1266-1274
Improved epicardial cardiac fibroblast generation from iPSCs.
Whitehead AJ, Hocker JD, Ren B, Engler AJ
Journal of molecular and cellular cardiology 2021 Nov 24;164:58-68
Journal of molecular and cellular cardiology 2021 Nov 24;164:58-68
Protection of CAPE-pNO2 Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Wan Q, Zhang L, Zhou Q, Han Y, Li Z, Li B
Inflammation 2021 Nov 24;
Inflammation 2021 Nov 24;
MyD88 in Macrophages Enhances Liver Fibrosis by Activation of NLRP3 Inflammasome in HSCs.
Ge S, Yang W, Chen H, Yuan Q, Liu S, Zhao Y, Zhang J
International journal of molecular sciences 2021 Nov 17;22(22)
International journal of molecular sciences 2021 Nov 17;22(22)
Lipoxin A4 inhibits ovalbumin-induced airway inflammation and airway remodeling in a mouse model of asthma.
Liu Y, Wei L, He C, Chen R, Meng L
Chemico-biological interactions 2021 Nov 1;349:109660
Chemico-biological interactions 2021 Nov 1;349:109660
Macrophage-derived exosomes mediate silica-induced pulmonary fibrosis by activating fibroblast in an endoplasmic reticulum stress-dependent manner.
Qin X, Lin X, Liu L, Li Y, Li X, Deng Z, Chen H, Chen H, Niu Z, Li Z, Hu Y
Journal of cellular and molecular medicine 2021 May;25(9):4466-4477
Journal of cellular and molecular medicine 2021 May;25(9):4466-4477
MiR-155 promotes colitis-associated intestinal fibrosis by targeting HBP1/Wnt/β-catenin signalling pathway.
Li N, Ouyang Y, Xu X, Yuan Z, Liu C, Zhu Z
Journal of cellular and molecular medicine 2021 May;25(10):4765-4775
Journal of cellular and molecular medicine 2021 May;25(10):4765-4775
Fluorofenidone inhibits epithelial-mesenchymal transition in human lens epithelial cell line FHL 124: a promising therapeutic strategy against posterior capsular opacification.
Zhuang H, Zheng NX, Lin L, Zhang WZ, Zhang WY, Yu QQ, Xu W
Arquivos brasileiros de oftalmologia 2021 May-Jun;84(3):258-266
Arquivos brasileiros de oftalmologia 2021 May-Jun;84(3):258-266
Splicing factor SRSF6 mediates pleural fibrosis.
Liang LM, Xiong L, Cheng PP, Chen SJ, Feng X, Zhou YY, Niu Q, Wang M, Chen Q, Song LJ, Yu F, He XL, Xiang F, Wang X, Ye H, Ma WL
JCI insight 2021 May 24;6(10)
JCI insight 2021 May 24;6(10)
Adiponectin Alleviates Intestinal Fibrosis by Enhancing AMP-Activated Protein Kinase Phosphorylation.
Xie M, Xiong Z, Yin S, Xiong J, Li X, Jin L, Zhang F, Chen H, Lan P, Lian L
Digestive diseases and sciences 2021 May 19;
Digestive diseases and sciences 2021 May 19;
Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy.
Zhang L, He J, Wang J, Liu J, Chen Z, Deng B, Wei L, Wu H, Liang B, Li H, Huang Y, Lu L, Yang Z, Xian S, Wang L
Cell death & disease 2021 May 11;12(5):470
Cell death & disease 2021 May 11;12(5):470
Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways.
Zhao B, Li S, Guo Z, Chen Z, Zhang X, Xu C, Chen J, Wei C
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):370-380
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):370-380
ADAMTS13 inhibits oxidative stress and ameliorates progressive chronic kidney disease following ischaemia/reperfusion injury.
Zhou S, Guo J, Zhao L, Liao Y, Zhou Q, Cui Y, Hu W, Chen J, Ren X, Wei Q, Jiang S, Zheng Y, Li L, Wilcox CS, Persson PB, Patzak A, Tian J, Yin Lai E
Acta physiologica (Oxford, England) 2021 Mar;231(3):e13586
Acta physiologica (Oxford, England) 2021 Mar;231(3):e13586
Umbilical cord-derived mesenchymal stem cells exert anti-fibrotic action on hypertrophic scar-derived fibroblasts in co-culture by inhibiting the activation of the TGF β1/Smad3 pathway.
Meng X, Gao X, Chen X, Yu J
Experimental and therapeutic medicine 2021 Mar;21(3):210
Experimental and therapeutic medicine 2021 Mar;21(3):210
Aptamer-SH2 superbinder-based targeted therapy for pancreatic ductal adenocarcinoma.
Liu AD, Zhou J, Bi XY, Hou GQ, Li SS, Chen Q, Xu H, Cao X
Clinical and translational medicine 2021 Mar;11(3):e337
Clinical and translational medicine 2021 Mar;11(3):e337
SAIL: a new conserved anti-fibrotic lncRNA in the heart.
Luo S, Zhang M, Wu H, Ding X, Li D, Dong X, Hu X, Su S, Shang W, Wu J, Xiao H, Yang W, Zhang Q, Zhang J, Lu Y, Pan Z
Basic research in cardiology 2021 Mar 6;116(1):15
Basic research in cardiology 2021 Mar 6;116(1):15
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Han D, Xu Y, Peng WP, Feng F, Wang Z, Gu C, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Concentrated exosomes from menstrual blood-derived stromal cells improves ovarian activity in a rat model of premature ovarian insufficiency.
Zhang S, Huang B, Su P, Chang Q, Li P, Song A, Zhao X, Yuan Z, Tan J
Stem cell research & therapy 2021 Mar 12;12(1):178
Stem cell research & therapy 2021 Mar 12;12(1):178
WISP-1 induced by mechanical stress contributes to fibrosis and hypertrophy of the ligamentum flavum through Hedgehog-Gli1 signaling.
Sun C, Ma Q, Yin J, Zhang H, Liu X
Experimental & molecular medicine 2021 Jun;53(6):1068-1079
Experimental & molecular medicine 2021 Jun;53(6):1068-1079
HIF-1α is necessary for activation and tumour-promotion effect of cancer-associated fibroblasts in lung cancer.
Zhang Y, Bian Y, Wang Y, Wang Y, Duan X, Han Y, Zhang L, Wang F, Gu Z, Qin Z
Journal of cellular and molecular medicine 2021 Jun;25(12):5457-5469
Journal of cellular and molecular medicine 2021 Jun;25(12):5457-5469
Role and mechanism of TXNIP in ageing-related renal fibrosis.
He Q, Li Y, Zhang W, Chen J, Deng W, Liu Q, Liu Y, Liu D
Mechanisms of ageing and development 2021 Jun;196:111475
Mechanisms of ageing and development 2021 Jun;196:111475
Pre-emptive pharmacological inhibition of fatty acid-binding protein 4 attenuates kidney fibrosis by reprogramming tubular lipid metabolism.
Chen Y, Dai Y, Song K, Huang Y, Zhang L, Zhang C, Yan Q, Gao H
Cell death & disease 2021 Jun 3;12(6):572
Cell death & disease 2021 Jun 3;12(6):572
Comparison of chondrogenesis-related biological behaviors between human urine-derived stem cells and human bone marrow mesenchymal stem cells from the same individual.
Sun J, Xing F, Zou M, Gong M, Li L, Xiang Z
Stem cell research & therapy 2021 Jun 28;12(1):366
Stem cell research & therapy 2021 Jun 28;12(1):366
Mesenchymal stem cells ameliorate silica-induced pulmonary fibrosis by inhibition of inflammation and epithelial-mesenchymal transition.
Wei J, Zhao Q, Yang G, Huang R, Li C, Qi Y, Hao C, Yao W
Journal of cellular and molecular medicine 2021 Jun 2;
Journal of cellular and molecular medicine 2021 Jun 2;
Nrf2 activation is involved in osteogenic differentiation of periodontal ligament stem cells under cyclic mechanical stretch.
Xi X, Zhao Y, Liu H, Li Z, Chen S, Liu D
Experimental cell research 2021 Jun 15;403(2):112598
Experimental cell research 2021 Jun 15;403(2):112598
Vincristine attenuates cardiac fibrosis through the inhibition of NLRP3 inflammasome activation.
Ge C, Cheng Y, Fan Y, He Y
Clinical science (London, England : 1979) 2021 Jun 11;135(11):1409-1426
Clinical science (London, England : 1979) 2021 Jun 11;135(11):1409-1426
Chloride channel accessory 1 integrates chloride channel activity and mTORC1 in aging-related kidney injury.
Lee HJ, Donati A, Feliers D, Sun Y, Ding Y, Madesh M, Salmon AB, Ikeno Y, Ross C, O'Connor CL, Ju W, Bitzer M, Chen Y, Choudhury GG, Singh BB, Sharma K, Kasinath BS
Aging cell 2021 Jul;20(7):e13407
Aging cell 2021 Jul;20(7):e13407
Periplocymarin protects against myocardial fibrosis induced by β-adrenergic activation in mice.
Yun W, Qian L, Yuan R, Xu H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111562
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111562
C188-9 reduces TGF-β1-induced fibroblast activation and alleviates ISO-induced cardiac fibrosis in mice.
Liu J, Jin Y, Wang B, Zhang J, Zuo S
FEBS open bio 2021 Jul;11(7):2033-2040
FEBS open bio 2021 Jul;11(7):2033-2040
Dopamine D1 receptor alleviates doxorubicin-induced cardiac injury by inhibiting NLRP3 inflammasome.
Liu J, Jin Y, Wang B, Wang Y, Zuo S, Zhang J
Biochemical and biophysical research communications 2021 Jul 5;561:7-13
Biochemical and biophysical research communications 2021 Jul 5;561:7-13
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Wu M, Chen W, Miao M, Jin Q, Zhang S, Bai M, Fan J, Zhang Y, Zhang A, Jia Z, Huang S
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.
Xun J, Li C, Liu M, Mei Y, Zhou Q, Wu B, Xie F, Liu Y, Dai R
Stem cell research & therapy 2021 Jul 27;12(1):424
Stem cell research & therapy 2021 Jul 27;12(1):424
Huoxin Pill inhibits isoproterenol-induced transdifferentiation and collagen synthesis in cardiac fibroblasts through the TGF-β/Smads pathway.
Peng M, Yang M, Lu Y, Lin S, Gao H, Xie L, Huang B, Chen D, Shen A, Shen Z, Peng J, Chu J
Journal of ethnopharmacology 2021 Jul 15;275:114061
Journal of ethnopharmacology 2021 Jul 15;275:114061
SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation.
Huang R, Hao C, Wang D, Zhao Q, Li C, Wang C, Yao W
Toxicology and applied pharmacology 2021 Jul 1;422:115559
Toxicology and applied pharmacology 2021 Jul 1;422:115559
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Chen C, Gu J, Wang J, Wu Y, Yang A, Chen T, Zhou T, Liu Z
International immunopharmacology 2021 Jan;90:107206
International immunopharmacology 2021 Jan;90:107206
Effect of human umbilical cord-derived mesenchymal stem cells on murine model of bronchiolitis obliterans like injury.
Lin J, Deng H, Zhang Y, Zou L, Fu Z, Dai J
Pediatric pulmonology 2021 Jan;56(1):129-137
Pediatric pulmonology 2021 Jan;56(1):129-137
Tormentic acid inhibits hepatic stellate cells activation via blocking PI3K/Akt/mTOR and NF-κB signalling pathways.
Lin X, Li Y, Zhang X, Wei Y, Wen S, Lu Z, Huang Q, Wei J
Cell biochemistry and function 2021 Jan;39(1):77-87
Cell biochemistry and function 2021 Jan;39(1):77-87
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Tian D, Teng X, Jin S, Chen Y, Xue H, Xiao L, Wu Y
Journal of advanced research 2021 Jan;27:115-125
Journal of advanced research 2021 Jan;27:115-125
Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway.
Lv W, Wu M, Ren Y, Luo X, Hu W, Zhang Q, Wu Y
Molecular medicine reports 2021 Jan;23(1)
Molecular medicine reports 2021 Jan;23(1)
Citrate regulates extracellular matrix mineralization during osteoblast differentiation in vitro.
Wu X, Dai H, Yu S, Zhao Y, Long Y, Li W, Tu J
Journal of inorganic biochemistry 2021 Jan;214:111269
Journal of inorganic biochemistry 2021 Jan;214:111269
Naringin attenuates renal interstitial fibrosis by regulating the TGF-β/Smad signaling pathway and inflammation.
Wang R, Wu G, Dai T, Lang Y, Chi Z, Yang S, Dong D
Experimental and therapeutic medicine 2021 Jan;21(1):66
Experimental and therapeutic medicine 2021 Jan;21(1):66
Responsive and activable nanomedicines for remodeling the tumor microenvironment.
Zhang Y, Han X, Nie G
Nature protocols 2021 Jan;16(1):405-430
Nature protocols 2021 Jan;16(1):405-430
Paroxetine Attenuates Cardiac Hypertrophy Via Blocking GRK2 and ADRB1 Interaction in Hypertension.
Sun X, Zhou M, Wen G, Huang Y, Wu J, Peng L, Jiang W, Yuan H, Lu Y, Cai J
Journal of the American Heart Association 2021 Jan 5;10(1):e016364
Journal of the American Heart Association 2021 Jan 5;10(1):e016364
Bortezomib limits renal allograft interstitial fibrosis by inhibiting NF-κB/TNF-α/Akt/mTOR/P70S6K/Smurf2 pathway via IκBα protein stabilization.
Suo C, Gui Z, Wang Z, Zhou J, Zheng M, Chen H, Fei S, Gu M, Tan R
Clinical science (London, England : 1979) 2021 Jan 15;135(1):53-69
Clinical science (London, England : 1979) 2021 Jan 15;135(1):53-69
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Dai W, Wang M, Wang P, Wen J, Wang J, Cha S, Xiao X, He Y, Shu R, Bai D
International journal of molecular medicine 2021 Feb;47(2):607-620
International journal of molecular medicine 2021 Feb;47(2):607-620
Silencing of METTL3 attenuates cardiac fibrosis induced by myocardial infarction via inhibiting the activation of cardiac fibroblasts.
Li T, Zhuang Y, Yang W, Xie Y, Shang W, Su S, Dong X, Wu J, Jiang W, Zhou Y, Li Y, Zhou X, Zhang M, Lu Y, Pan Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21162
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21162
FoxM1 promotes Wnt/β-catenin pathway activation and renal fibrosis via transcriptionally regulating multi-Wnts expressions.
Xie H, Miao N, Xu D, Zhou Z, Ni J, Yin F, Wang Y, Cheng Q, Chen P, Li J, Zheng P, Zhou L, Liu J, Zhang W, Wang X, Lu L
Journal of cellular and molecular medicine 2021 Feb;25(4):1958-1971
Journal of cellular and molecular medicine 2021 Feb;25(4):1958-1971
Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice.
Liu YS, Yang Q, Li S, Luo L, Liu HY, Li XY, Gao ZN
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Proximal tubular epithelial insulin receptor mediates high-fat diet-induced kidney injury.
Lee HJ, Mariappan MM, Norton L, Bakewell T, Feliers D, Oh SB, Donati A, Rubannelsonkumar CS, Venkatachalam MA, Harris SE, Rubera I, Tauc M, Ghosh Choudhury G, Kahn CR, Sharma K, DeFronzo RA, Kasinath BS
JCI insight 2021 Feb 8;6(3)
JCI insight 2021 Feb 8;6(3)
Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats.
An R, Wang X, Yang L, Zhang J, Wang N, Xu F, Hou Y, Zhang H, Zhang L
Toxicology 2021 Feb 15;449:152665
Toxicology 2021 Feb 15;449:152665
Leonurine Attenuates Myocardial Fibrosis Through Upregulation of miR-29a-3p in Mice Post-myocardial Infarction.
Wang R, Peng L, Lv D, Shang F, Yan J, Li G, Li D, Ouyang J, Yang J
Journal of cardiovascular pharmacology 2021 Feb 1;77(2):189-199
Journal of cardiovascular pharmacology 2021 Feb 1;77(2):189-199
Ginsenoside Rb1 attenuates age-associated vascular impairment by modulating the Gas6 pathway.
Ke S, Wu L, Wang M, Liu D, Shi G, Zhu J, Qian X
Pharmaceutical biology 2021 Dec;59(1):1369-1377
Pharmaceutical biology 2021 Dec;59(1):1369-1377
Epigallocatechin gallate (EGCG) attenuates myocardial hypertrophy and fibrosis induced by transverse aortic constriction via inhibiting the Akt/mTOR pathway.
Cui Y, Wang Y, Liu G
Pharmaceutical biology 2021 Dec;59(1):1305-1313
Pharmaceutical biology 2021 Dec;59(1):1305-1313
Adipose-derived mesenchymal stem cell exosomes inhibit transforming growth factor-β1-induced collagen synthesis in oral mucosal fibroblasts.
Liu J, Li F, Liu B, Yao Z, Li L, Liu G, Peng L, Wang Y, Huang J
Experimental and therapeutic medicine 2021 Dec;22(6):1419
Experimental and therapeutic medicine 2021 Dec;22(6):1419
Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.
Zhao X, Wang J, Tang L, Li P, Ru J, Bai Y
Bioengineered 2021 Dec;12(1):589-600
Bioengineered 2021 Dec;12(1):589-600
MicroRNA-210-5p alleviates cardiac fibrosis via targeting transforming growth factor-beta type I receptor in rats on high sodium chloride (NaCl)-based diet.
Zhao K, Mao Y, Ye X, Ma J, Sun L, Li P, Li Y
European journal of pharmacology 2021 Dec 5;912:174587
European journal of pharmacology 2021 Dec 5;912:174587
The application of human periodontal ligament stem cells and biomimetic silk scaffold for in situ tendon regeneration.
Chen J, Mo Q, Sheng R, Zhu A, Ling C, Luo Y, Zhang A, Chen Z, Yao Q, Cai Z, Zhang W
Stem cell research & therapy 2021 Dec 4;12(1):596
Stem cell research & therapy 2021 Dec 4;12(1):596
Deficiency of CARMA3 attenuates the development of bleomycin induced pulmonary fibrosis.
Wu Y, Qi Y, Qiu Z, Chen W
Biochemical and biophysical research communications 2021 Dec 3;581:81-88
Biochemical and biophysical research communications 2021 Dec 3;581:81-88
A suitable silicosis mouse model was constructed by repeated inhalation of silica dust via nose.
Li B, Mu M, Sun Q, Cao H, Liu Q, Liu J, Zhang J, Xu K, Hu D, Tao X, Wang J
Toxicology letters 2021 Dec 15;353:1-12
Toxicology letters 2021 Dec 15;353:1-12
Enzymatically crosslinked silk-nanosilicate reinforced hydrogel with dual-lineage bioactivity for osteochondral tissue engineering.
Zhang W, Zhang Y, Zhang A, Ling C, Sheng R, Li X, Yao Q, Chen J
Materials science & engineering. C, Materials for biological applications 2021 Aug;127:112215
Materials science & engineering. C, Materials for biological applications 2021 Aug;127:112215
Protein tyrosine phosphatase 1B regulates fibroblasts proliferation, motility and extracellular matrix synthesis via the MAPK/ERK signalling pathway in keloid.
Qian L, Wang Q, Wei C, Wang L, Yang Y, Deng X, Liu J, Qi F
Experimental dermatology 2021 Aug 9;
Experimental dermatology 2021 Aug 9;
Nintedanib downregulates the transition of cultured systemic sclerosis fibrocytes into myofibroblasts and their pro-fibrotic activity.
Cutolo M, Gotelli E, Montagna P, Tardito S, Paolino S, Pizzorni C, Sulli A, Smith V, Soldano S
Arthritis research & therapy 2021 Aug 3;23(1):205
Arthritis research & therapy 2021 Aug 3;23(1):205
ER-anchored CRTH2 antagonizes collagen biosynthesis and organ fibrosis via binding LARP6.
Zuo S, Wang B, Liu J, Kong D, Cui H, Jia Y, Wang C, Xu X, Chen G, Wang Y, Yang L, Zhang K, Ai D, Du J, Shen Y, Yu Y
The EMBO journal 2021 Aug 16;40(16):e107403
The EMBO journal 2021 Aug 16;40(16):e107403
Inhibition of DNA methylation de-represses peroxisome proliferator-activated receptor-γ and attenuates pulmonary fibrosis.
Wei A, Gao Q, Chen F, Zhu X, Chen X, Zhang L, Su X, Dai J, Shi Y, Cao W
British journal of pharmacology 2021 Aug 11;
British journal of pharmacology 2021 Aug 11;
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
Zhou S, He Y, Zhang W, Xiong Y, Jiang L, Wang J, Cui X, Qu Y, Ge F
Journal of ethnopharmacology 2021 Aug 10;276:114189
Journal of ethnopharmacology 2021 Aug 10;276:114189
Adenosine A3 receptor activated in H2O2 oxidative stress of primary open-angle glaucoma.
Zhou Z, Gao Z, Yan W, Zhang Y, Huang J, Xiong K
Annals of translational medicine 2021 Apr;9(7):526
Annals of translational medicine 2021 Apr;9(7):526
Matrine attenuates pathological cardiac fibrosis via RPS5/p38 in mice.
Zhang X, Hu C, Zhang N, Wei WY, Li LL, Wu HM, Ma ZG, Tang QZ
Acta pharmacologica Sinica 2021 Apr;42(4):573-584
Acta pharmacologica Sinica 2021 Apr;42(4):573-584
Overexpression of Fgf8 in the epidermis inhibits hair follicle development.
Wang Z, Chen Y, Chen M, Zhang Y
Experimental dermatology 2021 Apr;30(4):494-502
Experimental dermatology 2021 Apr;30(4):494-502
HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.
Cao Z, Cheng Y, Wang J, Liu Y, Yang R, Jiang W, Li H, Zhang X
Journal of experimental & clinical cancer research : CR 2021 Apr 1;40(1):118
Journal of experimental & clinical cancer research : CR 2021 Apr 1;40(1):118
The Antiproliferative and Antifibrotic Effects of Cisplatin on Primary Human Vocal Fold Fibroblasts.
Xu H, Wang Q, Fan GK
ORL; journal for oto-rhino-laryngology and its related specialties 2020;82(4):188-200
ORL; journal for oto-rhino-laryngology and its related specialties 2020;82(4):188-200
CDKN2a/p16 Antagonizes Hepatic Stellate Cell Activation and Liver Fibrosis by Modulating ROS Levels.
Lv F, Li N, Kong M, Wu J, Fan Z, Miao D, Xu Y, Ye Q, Wang Y
Frontiers in cell and developmental biology 2020;8:176
Frontiers in cell and developmental biology 2020;8:176
Ginsenoside Rb1 Ameliorates Age-Related Myocardial Dysfunction by Regulating the NF-[Formula: see text]B Signaling Pathway.
Ke SY, Liu DH, Wu L, Yu XG, Wang M, Shi GY, Wen RH, Zhou B, Hao BS, Liu Y, Zhu JM, Qian XX
The American journal of Chinese medicine 2020;48(6):1369-1383
The American journal of Chinese medicine 2020;48(6):1369-1383
Protective Effects of MitoTEMPO on Nonalcoholic Fatty Liver Disease via Regulating Myeloid-Derived Suppressor Cells and Inflammation in Mice.
Wu J, Zheng L, Mo J, Yao X, Fan C, Bao Y
BioMed research international 2020;2020:9329427
BioMed research international 2020;2020:9329427
Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway.
Luan Y, Cui K, Tang Z, Ruan Y, Liu K, Wang T, Chen Z, Wang S, Liu J
Oxidative medicine and cellular longevity 2020;2020:6834236
Oxidative medicine and cellular longevity 2020;2020:6834236
Exposure to Air Pollution Exacerbates Inflammation in Rats with Preexisting COPD.
Wang J, Li Y, Zhao P, Tian Y, Liu X, He H, Jia R, Oliver BG, Li J
Mediators of inflammation 2020;2020:4260204
Mediators of inflammation 2020;2020:4260204
Withaferin A Exerts Preventive Effect on Liver Fibrosis through Oxidative Stress Inhibition in a Sirtuin 3-Dependent Manner.
Gu J, Chen C, Wang J, Chen T, Yao W, Yan T, Liu Z
Oxidative medicine and cellular longevity 2020;2020:2452848
Oxidative medicine and cellular longevity 2020;2020:2452848
miR-876 Inhibits EMT and Liver Fibrosis via POSTN to Suppress Metastasis in Hepatocellular Carcinoma.
Chen K, Li Z, Zhang M, Wang B, Peng T, Shen Y, Zhang J, Ye J, Liu Y, Tang D, Peng M, Ma D, Xiao Z, Zhang Y, Jin W, Li X
BioMed research international 2020;2020:1964219
BioMed research international 2020;2020:1964219
Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line.
Sun L, Qu L, Brigstock DR, Li H, Li Y, Gao R
International journal of medical sciences 2020;17(1):137-144
International journal of medical sciences 2020;17(1):137-144
Resveratrol promotes osteoblastic differentiation in a rat model of postmenopausal osteoporosis by regulating autophagy.
Wang W, Zhang LM, Guo C, Han JF
Nutrition & metabolism 2020;17:29
Nutrition & metabolism 2020;17:29
Galectin-3 Induces Atrial Fibrosis by Activating the TGF-β1/Smad Pathway in Patients with Atrial Fibrillation.
Xiao M, Zhang M, Bie M, Wang X, Guo J, Xiao H
Cardiology 2020;145(7):446-455
Cardiology 2020;145(7):446-455
Inactivation of Pancreatic Stellate Cells by Exendin-4 Inhibits the Migration and Invasion of Pancreatic Cancer Cells.
Yan M, Shen M, Xu L, Huang J, He G, An M, Li X, Gao Z, Meng X
OncoTargets and therapy 2020;13:9455-9463
OncoTargets and therapy 2020;13:9455-9463
Dexmedetomidine Exerted Anti-arrhythmic Effects in Rat With Ischemic Cardiomyopathy via Upregulation of Connexin 43 and Reduction of Fibrosis and Inflammation.
Wu SJ, Lin ZH, Lin YZ, Rao ZH, Lin JF, Wu LP, Li L
Frontiers in physiology 2020;11:33
Frontiers in physiology 2020;11:33
Aerosolized Thyroid Hormone Prevents Radiation Induced Lung Fibrosis.
Li L, Nie X, Yi M, Qin W, Li F, Wu B, Yuan X
Frontiers in oncology 2020;10:528686
Frontiers in oncology 2020;10:528686
Selective targeting of ubiquitination and degradation of PARP1 by E3 ubiquitin ligase WWP2 regulates isoproterenol-induced cardiac remodeling.
Zhang N, Zhang Y, Qian H, Wu S, Cao L, Sun Y
Cell death and differentiation 2020 Sep;27(9):2605-2619
Cell death and differentiation 2020 Sep;27(9):2605-2619
miR-26a attenuates cardiac apoptosis and fibrosis by targeting ataxia-telangiectasia mutated in myocardial infarction.
Chiang MH, Liang CJ, Lin LC, Yang YF, Huang CC, Chen YH, Kao HL, Chen YC, Ke SR, Lee CW, Lin MS, Chen YL
Journal of cellular physiology 2020 Sep;235(9):6085-6102
Journal of cellular physiology 2020 Sep;235(9):6085-6102
LncRNA TRPC7-AS1 regulates nucleus pulposus cellular senescence and ECM synthesis via competing with HPN for miR-4769-5p binding.
Wang X, Li D, Wu H, Liu F, Liu F, Zhang Q, Li J
Mechanisms of ageing and development 2020 Sep;190:111293
Mechanisms of ageing and development 2020 Sep;190:111293
hUMSCs regulate the differentiation of ovarian stromal cells via TGF-β1/Smad3 signaling pathway to inhibit ovarian fibrosis to repair ovarian function in POI rats.
Cui L, Bao H, Liu Z, Man X, Liu H, Hou Y, Luo Q, Wang S, Fu Q, Zhang H
Stem cell research & therapy 2020 Sep 7;11(1):386
Stem cell research & therapy 2020 Sep 7;11(1):386
Inhibition of p66Shc Oxidative Signaling via CA-Induced Upregulation of miR-203a-3p Alleviates Liver Fibrosis Progression.
Wang Z, Zhao Y, Zhao H, Zhou J, Feng D, Tang F, Li Y, Lv L, Chen Z, Ma X, Tian X, Yao J
Molecular therapy. Nucleic acids 2020 Sep 4;21:751-763
Molecular therapy. Nucleic acids 2020 Sep 4;21:751-763
Polystyrene microplastics cause cardiac fibrosis by activating Wnt/β-catenin signaling pathway and promoting cardiomyocyte apoptosis in rats.
Li Z, Zhu S, Liu Q, Wei J, Jin Y, Wang X, Zhang L
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt A):115025
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt A):115025
MSC-derived exosomes protect against oxidative stress-induced skin injury via adaptive regulation of the NRF2 defense system.
Wang T, Jian Z, Baskys A, Yang J, Li J, Guo H, Hei Y, Xian P, He Z, Li Z, Li N, Long Q
Biomaterials 2020 Oct;257:120264
Biomaterials 2020 Oct;257:120264
Endothelin receptors promote schistosomiasis-induced hepatic fibrosis via splenic B cells.
Kong H, He J, Guo S, Song Q, Xiang D, Tao R, Yu H, Chen G, Huang Z, Ning Q, Huang J
PLoS pathogens 2020 Oct;16(10):e1008947
PLoS pathogens 2020 Oct;16(10):e1008947
Si-Miao-Yong-An Decoction attenuates isoprenaline-induced myocardial fibrosis in AMPK-driven Akt/mTOR and TGF-β/SMAD3 pathways.
Zhao Y, Sun D, Chen Y, Zhan K, Meng Q, Zhang X, Zhu L, Yao X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110522
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110522
TGFβ acts through PDGFRβ to activate mTORC1 via the Akt/PRAS40 axis and causes glomerular mesangial cell hypertrophy and matrix protein expression.
Maity S, Das F, Kasinath BS, Ghosh-Choudhury N, Ghosh Choudhury G
The Journal of biological chemistry 2020 Oct 16;295(42):14262-14278
The Journal of biological chemistry 2020 Oct 16;295(42):14262-14278
MAD2B contributes to parietal epithelial cell activation and crescentic glomerulonephritis via Skp2.
Ye C, Xiong W, Lei CT, Tang H, Su H, Yi F, Zhang C
American journal of physiology. Renal physiology 2020 Oct 1;319(4):F636-F646
American journal of physiology. Renal physiology 2020 Oct 1;319(4):F636-F646
Citri Reticulatae Pericarpium protects against isoproterenol-induced chronic heart failure via activation of PPARγ.
Cheng H, Wu X, Ni G, Wang S, Peng W, Zhang H, Gao J, Li X
Annals of translational medicine 2020 Nov;8(21):1396
Annals of translational medicine 2020 Nov;8(21):1396
Crosstalk between pleural mesothelial cell and lung fibroblast contributes to pulmonary fibrosis.
Liu F, Yu F, Lu YZ, Cheng PP, Liang LM, Wang M, Chen SJ, Huang Y, Song LJ, He XL, Xiong L, Xin JB, Ma WL, Ye H
Biochimica et biophysica acta. Molecular cell research 2020 Nov;1867(11):118806
Biochimica et biophysica acta. Molecular cell research 2020 Nov;1867(11):118806
Magnesium Calcium Phosphate Cement Incorporating Citrate for Vascularized Bone Regeneration.
Wu X, Dai H, Yu S, Zhao Y, Long Y, Li W, Tu J
ACS biomaterials science & engineering 2020 Nov 9;6(11):6299-6308
ACS biomaterials science & engineering 2020 Nov 9;6(11):6299-6308
Involvement of FATP2-mediated tubular lipid metabolic reprogramming in renal fibrogenesis.
Chen Y, Yan Q, Lv M, Song K, Dai Y, Huang Y, Zhang L, Zhang C, Gao H
Cell death & disease 2020 Nov 20;11(11):994
Cell death & disease 2020 Nov 20;11(11):994
Caveolin-1 stabilizes ATP7A, a copper transporter for extracellular SOD, in vascular tissue to maintain endothelial function.
Sudhahar V, Okur MN, O'Bryan JP, Minshall RD, Fulton D, Ushio-Fukai M, Fukai T
American journal of physiology. Cell physiology 2020 Nov 1;319(5):C933-C944
American journal of physiology. Cell physiology 2020 Nov 1;319(5):C933-C944
TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.
Xu S, Mao Y, Wu J, Feng J, Li J, Wu L, Yu Q, Zhou Y, Zhang J, Chen J, Ji J, Chen K, Wang F, Dai W, Fan X, Guo C
Journal of cellular and molecular medicine 2020 May;24(9):5224-5237
Journal of cellular and molecular medicine 2020 May;24(9):5224-5237
Melatonin up-regulates bone marrow mesenchymal stem cells osteogenic action but suppresses their mediated osteoclastogenesis via MT2 -inactivated NF-κB pathway.
Zhou Y, Wang C, Si J, Wang B, Zhang D, Ding D, Zhang J, Wang H
British journal of pharmacology 2020 May;177(9):2106-2122
British journal of pharmacology 2020 May;177(9):2106-2122
Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models.
Liu YC, Wang HL, Huang YZ, Weng YH, Chen RS, Tsai WC, Yeh TH, Lu CS, Chen YL, Lin YW, Chen YJ, Hsu CC, Chiu CH, Chiu CC
Biochemical pharmacology 2020 May;175:113919
Biochemical pharmacology 2020 May;175:113919
Comprehensive circRNA expression profile and construction of circRNA-related ceRNA network in cardiac fibrosis.
Gu X, Jiang YN, Wang WJ, Zhang J, Shang DS, Sun CB, Tian JT, Tian JW, Yu B, Zhang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109944
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109944
Lactoferrin Contributes a Renoprotective Effect in Acute Kidney Injury and Early Renal Fibrosis.
Hsu YH, Chiu IJ, Lin YF, Chen YJ, Lee YH, Chiu HW
Pharmaceutics 2020 May 8;12(5)
Pharmaceutics 2020 May 8;12(5)
HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis.
Zhu Q, Dong H, Bukhari AA, Zhao A, Li M, Sun Y, Zhang X, Cao C, Su D, Liang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4591-4601
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4591-4601
G protein-coupled receptor kinase-2: A potential biomarker for early diabetic cardiomyopathy.
Lai S, Fu X, Yang S, Zhang S, Lin Q, Zhang M, Chen H
Journal of diabetes 2020 Mar;12(3):247-258
Journal of diabetes 2020 Mar;12(3):247-258
Local SDF-1α application enhances the therapeutic efficacy of BMSCs transplantation in osteoporotic bone healing.
Liu Q, Wen Y, Qiu J, Zhang Z, Jin Z, Cao M, Jiao Y, Yang H
Heliyon 2020 Jun;6(6):e04347
Heliyon 2020 Jun;6(6):e04347
Epithelial-mesenchymal transition and metastasis of colon cancer cells induced by the FAK pathway in cancer-associated fibroblasts.
Xuefeng X, Hou MX, Yang ZW, Agudamu A, Wang F, Su XL, Li X, Shi L, Terigele T, Bao LL, Wu XL
The Journal of international medical research 2020 Jun;48(6):300060520931242
The Journal of international medical research 2020 Jun;48(6):300060520931242
Meprin-α (Mep1A) enhances TNF-α secretion by mast cells and aggravates abdominal aortic aneurysms.
Gao R, Liu D, Guo W, Ge W, Fan T, Li B, Gao P, Liu B, Zheng Y, Wang J
British journal of pharmacology 2020 Jun;177(12):2872-2885
British journal of pharmacology 2020 Jun;177(12):2872-2885
LncRNA SNHG7 promotes cardiac remodeling by upregulating ROCK1 via sponging miR-34-5p.
Wang J, Zhang S, Li X, Gong M
Aging 2020 Jun 6;12(11):10441-10456
Aging 2020 Jun 6;12(11):10441-10456
High expression of AMAP1, an ARF6 effector, is associated with elevated levels of PD-L1 and fibrosis of pancreatic cancer.
Tsutaho A, Hashimoto A, Hashimoto S, Hata S, Kachi S, Hirano S, Sabe H
Cell communication and signaling : CCS 2020 Jun 24;18(1):101
Cell communication and signaling : CCS 2020 Jun 24;18(1):101
Administration of a mixture of triterpenoids from yeyachun and phenolic acids from danshen ameliorates carbon tetrachloride-induced liver fibrosis in mice by the regulation of intestinal flora.
Tan Y, Li Y, Zhou F, Guo J, Wang T, Shi Y, Yang Y, Lu J, Pei G
Journal of pharmacological sciences 2020 Jul;143(3):165-175
Journal of pharmacological sciences 2020 Jul;143(3):165-175
Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression.
Su C, Wang Q, Luo H, Jiao W, Tang J, Li L, Tian L, Chen X, Liu B, Yu X, Li S, Guo S, Wang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110132
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110132
Design, synthesis and discovery of 2(1H)-quinolone derivatives for the treatment of pulmonary fibrosis through inhibition of TGF-β/smad dependent and independent pathway.
Xue L, Deng D, Zheng S, Tang M, Yang Z, Pei H, Chen Y, Yang T, Liu K, Ye H, Chen L
European journal of medicinal chemistry 2020 Jul 1;197:112259
European journal of medicinal chemistry 2020 Jul 1;197:112259
Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.
Wang X, Lin L, Chai X, Wu Y, Li Y, Liu X
International journal of molecular medicine 2020 Jan;45(1):175-185
International journal of molecular medicine 2020 Jan;45(1):175-185
Left Atrial Appendage Fibrosis and 3-Year Clinical Outcomes in Atrial Fibrillation After Endoscopic Ablation: A Histologic Analysis.
Ma N, Lu R, Zhao D, Jiang Z, Tang M, Bao C, Mei J
The Annals of thoracic surgery 2020 Jan;109(1):69-76
The Annals of thoracic surgery 2020 Jan;109(1):69-76
The Effect of Mitomycin C on Reducing Endometrial Fibrosis for Intrauterine Adhesion.
Xu F, Shen X, Sun C, Xu X, Wang W, Zheng J
Medical science monitor : international medical journal of experimental and clinical research 2020 Jan 2;26:e920670
Medical science monitor : international medical journal of experimental and clinical research 2020 Jan 2;26:e920670
Fibroblasts Derived From Human Adipose Stem Cells Produce More Effective Extracellular Matrix and Migrate Faster Compared to Primary Dermal Fibroblasts.
Gersch RP, Raum JC, Calvert C, Percec I
Aesthetic surgery journal 2020 Jan 1;40(1):108-117
Aesthetic surgery journal 2020 Jan 1;40(1):108-117
Synthesis and discovery of new compounds bearing coumarin scaffold for the treatment of pulmonary fibrosis.
Deng D, Pei H, Lan T, Zhu J, Tang M, Xue L, Yang Z, Zheng S, Ye H, Chen L
European journal of medicinal chemistry 2020 Jan 1;185:111790
European journal of medicinal chemistry 2020 Jan 1;185:111790
Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis.
Fu S, Li Y, Wu Y, Yue Y, Yang D
The Journal of pharmacy and pharmacology 2020 Feb;72(2):227-235
The Journal of pharmacy and pharmacology 2020 Feb;72(2):227-235
Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury.
Zhang N, Zhang Y, Wu B, You S, Sun Y
Redox biology 2020 Feb;30:101419
Redox biology 2020 Feb;30:101419
Interaction of calcium binding protein S100A16 with myosin-9 promotes cytoskeleton reorganization in renal tubulointerstitial fibrosis.
Sun H, Zhao A, Li M, Dong H, Sun Y, Zhang X, Zhu Q, Bukhari AA, Cao C, Su D, Liu Y, Liang X
Cell death & disease 2020 Feb 24;11(2):146
Cell death & disease 2020 Feb 24;11(2):146
Suppression of p66Shc prevents hyperandrogenism-induced ovarian oxidative stress and fibrosis.
Wang D, Wang T, Wang R, Zhang X, Wang L, Xiang Z, Zhuang L, Shen S, Wang H, Gao Q, Wang Y
Journal of translational medicine 2020 Feb 17;18(1):84
Journal of translational medicine 2020 Feb 17;18(1):84
An all-silk-derived functional nanosphere matrix for sequential biomolecule delivery and in situ osteochondral regeneration.
Zhang W, Ling C, Zhang A, Liu H, Jiang Y, Li X, Sheng R, Yao Q, Chen J
Bioactive materials 2020 Dec;5(4):832-843
Bioactive materials 2020 Dec;5(4):832-843
Apremilast interferes with the TGFβ1-induced transition of human skin fibroblasts into profibrotic myofibroblasts: in vitro study.
Cutolo M, Soldano S, Montagna P, Martinelli G, Tardito S, Corallo C, Giordano N, Tavilla P, Cozzani E, Parodi A, Sulli A, Pizzorni C, Patane M, Smith V, Paolino S
Rheumatology (Oxford, England) 2020 Dec 1;59(12):3927-3938
Rheumatology (Oxford, England) 2020 Dec 1;59(12):3927-3938
LncRNA Gm16410 regulates PM2.5-induced lung Endothelial-Mesenchymal Transition via the TGF-β1/Smad3/p-Smad3 pathway.
Ma K, Li C, Xu J, Ren F, Xu X, Liu C, Niu B, Li F
Ecotoxicology and environmental safety 2020 Dec 1;205:111327
Ecotoxicology and environmental safety 2020 Dec 1;205:111327
Bioactive multi-engineered hydrogel offers simultaneous promise against antibiotic resistance and wound damage.
Zhang J, Ge J, Xu Y, Chen J, Zhou A, Sun L, Gao Y, Zhang Y, Gu T, Ning X
International journal of biological macromolecules 2020 Dec 1;164:4466-4474
International journal of biological macromolecules 2020 Dec 1;164:4466-4474
Morroniside attenuates high glucose-induced BMSC dysfunction by regulating the Glo1/AGE/RAGE axis.
Sun Y, Zhu Y, Liu X, Chai Y, Xu J
Cell proliferation 2020 Aug;53(8):e12866
Cell proliferation 2020 Aug;53(8):e12866
Atorvastatin attenuates TGF‑β1‑induced fibrogenesis by inhibiting Smad3 and MAPK signaling in human ventricular fibroblasts.
Du Y, Xiao H, Wan J, Wang X, Li T, Zheng S, Feng J, Ye Q, Li J, Li G, Fan Z
International journal of molecular medicine 2020 Aug;46(2):633-640
International journal of molecular medicine 2020 Aug;46(2):633-640
Biomineralizaion of hydroxyapatite on polyethylene terephthalate artificial ligaments promotes graft-bone healing after anterior cruciate ligament reconstruction: An in vitro and in vivo study.
Cai J, Ai C, Chen J, Chen S
Journal of biomaterials applications 2020 Aug;35(2):193-204
Journal of biomaterials applications 2020 Aug;35(2):193-204
Astaxanthin attenuates hepatic damage and mitochondrial dysfunction in non-alcoholic fatty liver disease by up-regulating the FGF21/PGC-1α pathway.
Wu L, Mo W, Feng J, Li J, Yu Q, Li S, Zhang J, Chen K, Ji J, Dai W, Wu J, Xu X, Mao Y, Guo C
British journal of pharmacology 2020 Aug;177(16):3760-3777
British journal of pharmacology 2020 Aug;177(16):3760-3777
Bone-Inspired Tube Filling Decellularized Matrix of Toad Cartilage Provided an Osteoinductive Microenvironment for Mesenchymal Stem Cells to Facilitate the Radius Defect Repair of Rabbit.
Xu HL, Yang WG, Chen PP, Chen R, Xue PP, Wang LF, Yuan JD, Yao Q, Chen B, Zhao YZ
Biotechnology journal 2020 Aug;15(8):e2000004
Biotechnology journal 2020 Aug;15(8):e2000004
Isoliquiritigenin inhibits TGF-β1-induced fibrogenesis through activating autophagy via PI3K/AKT/mTOR pathway in MRC-5 cells.
He J, Peng H, Wang M, Liu Y, Guo X, Wang B, Dai L, Cheng X, Meng Z, Yuan L, Cai F, Tang Y
Acta biochimica et biophysica Sinica 2020 Aug 5;52(8):810-820
Acta biochimica et biophysica Sinica 2020 Aug 5;52(8):810-820
Icotinib Attenuates Monocrotaline-Induced Pulmonary Hypertension by Preventing Pulmonary Arterial Smooth Muscle Cell Dysfunction.
Peng LY, Yu M, Yang MX, Liu P, Zhou H, Huang W, Kong H, Xie WP
American journal of hypertension 2020 Aug 4;33(8):775-783
American journal of hypertension 2020 Aug 4;33(8):775-783
Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.
Sun B, Wang X, Liu X, Wang L, Ren F, Wang X, Leng X
Antioxidants (Basel, Switzerland) 2020 Aug 25;9(9)
Antioxidants (Basel, Switzerland) 2020 Aug 25;9(9)
RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice.
Zhou Z, Ni J, Li J, Huo C, Miao N, Yin F, Cheng Q, Xu D, Xie H, Chen P, Zheng P, Zhang Y, Zhou L, Zhang W, Yu C, Liu J, Lu L
Journal of molecular medicine (Berlin, Germany) 2020 Apr;98(4):527-540
Journal of molecular medicine (Berlin, Germany) 2020 Apr;98(4):527-540
Pharmacologic inhibition of RGD-binding integrins ameliorates fibrosis and improves function following kidney injury.
Basta J, Robbins L, Stout L, Prinsen MJ, Griggs DW, Rauchman M
Physiological reports 2020 Apr;8(7):e14329
Physiological reports 2020 Apr;8(7):e14329
LncRNA MIAT/miR-133a-3p axis regulates atrial fibrillation and atrial fibrillation-induced myocardial fibrosis.
Yao L, Zhou B, You L, Hu H, Xie R
Molecular biology reports 2020 Apr;47(4):2605-2617
Molecular biology reports 2020 Apr;47(4):2605-2617
Downregulation of miR-96 suppresses the profibrogenic functions of cardiac fibroblasts induced by angiotensin II and attenuates atrial fibrosis by upregulating KLF13.
Su L, Yao Y, Song W
Human cell 2020 Apr;33(2):337-346
Human cell 2020 Apr;33(2):337-346
COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence.
Zhang CY, Duan JX, Yang HH, Sun CC, Zhong WJ, Tao JH, Guan XX, Jiang HL, Hammock BD, Hwang SH, Zhou Y, Guan CX
The FEBS journal 2020 Apr;287(8):1666-1680
The FEBS journal 2020 Apr;287(8):1666-1680
Long-term voluntary running prevents the onset of symptomatic Friedreich's ataxia in mice.
Zhao H, Lewellen BM, Wilson RJ, Cui D, Drake JC, Zhang M, Yan Z
Scientific reports 2020 Apr 8;10(1):6095
Scientific reports 2020 Apr 8;10(1):6095
Septin4 as an autophagy modulator regulates Angiotensin-II mediated VSMCs proliferation and migration.
Wang N, Xu F, Lu S, Zhang N, Sun Y
Biochemical and biophysical research communications 2020 Apr 30;525(2):272-279
Biochemical and biophysical research communications 2020 Apr 30;525(2):272-279
Silica particles disorganize the polarization of pulmonary macrophages in mice.
Zhao Y, Hao C, Bao L, Wang D, Li Y, Qu Y, Ding M, Zhao A, Yao W
Ecotoxicology and environmental safety 2020 Apr 15;193:110364
Ecotoxicology and environmental safety 2020 Apr 15;193:110364
Dysregulation of the Wnt Signaling Pathway and Synovial Stem Cell Dysfunction in Osteoarthritis Development.
Huang J, Chen C, Liang C, Luo P, Xia G, Zhang L, Wang X, Wen Z, Cao X, Wu S
Stem cells and development 2020 Apr 1;29(7):401-413
Stem cells and development 2020 Apr 1;29(7):401-413
Kartogenin hydrolysis product 4-aminobiphenyl distributes to cartilage and mediates cartilage regeneration.
Zhang S, Hu P, Liu T, Li Z, Huang Y, Liao J, Hamid MR, Wen L, Wang T, Mo C, Alini M, Grad S, Wang T, Chen D, Zhou G
Theranostics 2019;9(24):7108-7121
Theranostics 2019;9(24):7108-7121
Transplantation of adipose-derived stem cells overexpressing inducible nitric oxide synthase ameliorates diabetes mellitus-induced erectile dysfunction in rats.
Zhang Y, Yang J, Zhuan L, Zang G, Wang T, Liu J
PeerJ 2019;7:e7507
PeerJ 2019;7:e7507
Costunolide reduces glycolysis-associated activation of hepatic stellate cells via inhibition of hexokinase-2.
Ban D, Hua S, Zhang W, Shen C, Miao X, Liu W
Cellular & molecular biology letters 2019;24:52
Cellular & molecular biology letters 2019;24:52
Methane-Rich Saline Counteracts Cholestasis-Induced Liver Damage via Regulating the TLR4/NF-κB/NLRP3 Inflammasome Pathway.
Li Z, Chen D, Jia Y, Feng Y, Wang C, Tong Y, Cui R, Qu K, Liu C, Zhang J
Oxidative medicine and cellular longevity 2019;2019:6565283
Oxidative medicine and cellular longevity 2019;2019:6565283
Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways.
Liu N, Feng J, Lu X, Yao Z, Liu Q, Lv Y, Han Y, Deng J, Zhou Y
Mediators of inflammation 2019;2019:6175091
Mediators of inflammation 2019;2019:6175091
Indoxyl Sulfate Induces Renal Fibroblast Activation through a Targetable Heat Shock Protein 90-Dependent Pathway.
Milanesi S, Garibaldi S, Saio M, Ghigliotti G, Picciotto D, Ameri P, Garibotto G, Barisione C, Verzola D
Oxidative medicine and cellular longevity 2019;2019:2050183
Oxidative medicine and cellular longevity 2019;2019:2050183
A Biomimetic Model for Mineralization of Type-I Collagen Fibrils.
Yao S, Xu Y, Shao C, Nudelman F, Sommerdijk NAJM, Tang R
Methods in molecular biology (Clifton, N.J.) 2019;1944:39-54
Methods in molecular biology (Clifton, N.J.) 2019;1944:39-54
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
Dias HB, de Oliveira JR, Donadio MVF, Kimura S
PloS one 2019;14(9):e0222202
PloS one 2019;14(9):e0222202
Presence and function of stress granules in atrial fibrillation.
Dong G, Liang F, Sun B, Wang C, Liu Y, Guan X, Yang B, Xiu C, Yang N, Liu F, Lu T, Han W
PloS one 2019;14(4):e0213769
PloS one 2019;14(4):e0213769
A Novel Liposomal S-Propargyl-Cysteine: A Sustained Release of Hydrogen Sulfide Reducing Myocardial Fibrosis via TGF-β1/Smad Pathway.
Tran BH, Yu Y, Chang L, Tan B, Jia W, Xiong Y, Dai T, Zhong R, Zhang W, Le VM, Rose P, Wang Z, Mao Y, Zhu YZ
International journal of nanomedicine 2019;14:10061-10077
International journal of nanomedicine 2019;14:10061-10077
Dioscin ameliorates peritoneal fibrosis by inhibiting epithelial-to-mesenchymal transition of human peritoneal mesothelial cells via the TLR4/MyD88/NF-κB signaling pathway.
Shao Q, Jiang C, Xia Y, Zhao M, Zhang Q, Jin B, Liu J
International journal of clinical and experimental pathology 2019;12(3):867-875
International journal of clinical and experimental pathology 2019;12(3):867-875
A small molecule inhibitor MCC950 ameliorates kidney injury in diabetic nephropathy by inhibiting NLRP3 inflammasome activation.
Zhang C, Zhu X, Li L, Ma T, Shi M, Yang Y, Fan Q
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:1297-1309
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:1297-1309
Stachydrine Ameliorates Cardiac Fibrosis Through Inhibition of Angiotensin II/Transformation Growth Factor β1 Fibrogenic Axis.
Liu X, Shan X, Chen H, Li Z, Zhao P, Zhang C, Guo W, Xu M, Lu R
Frontiers in pharmacology 2019;10:538
Frontiers in pharmacology 2019;10:538
Exogenous angiotensin (1-7) directly inhibits epithelial-mesenchymal transformation induced by transforming growth factor-β1 in alveolar epithelial cells.
Shao M, Wen ZB, Yang HH, Zhang CY, Xiong JB, Guan XX, Zhong WJ, Jiang HL, Sun CC, Luo XQ, He XF, Zhou Y, Guan CX
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109193
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109193
lncRNA NR_038323 Suppresses Renal Fibrosis in Diabetic Nephropathy by Targeting the miR-324-3p/DUSP1 Axis.
Ge Y, Wang J, Wu D, Zhou Y, Qiu S, Chen J, Zhu X, Xiang X, Li H, Zhang D
Molecular therapy. Nucleic acids 2019 Sep 6;17:741-753
Molecular therapy. Nucleic acids 2019 Sep 6;17:741-753
Germacrane Sesquiterpenoids as a New Type of Anticardiac Fibrosis Agent Targeting Transforming Growth Factor β Type I Receptor.
Lou LL, Ni FQ, Chen L, Shaker S, Li W, Wang R, Tang GH, Yin S
Journal of medicinal chemistry 2019 Sep 12;62(17):7961-7975
Journal of medicinal chemistry 2019 Sep 12;62(17):7961-7975
Pioglitazone attenuates kidney fibrosis via miR-21-5p modulation.
Sun L, Xu T, Chen Y, Qu W, Sun D, Song X, Yuan Q, Yao L
Life sciences 2019 Sep 1;232:116609
Life sciences 2019 Sep 1;232:116609
Ghrelin Fights Against Titanium Particle-Induced Inflammatory Osteolysis Through Activation of β-Catenin Signaling Pathway.
Qu R, Chen X, Yuan Y, Wang W, Qiu C, Liu L, Li P, Zhang Z, Vasilev K, Liu L, Hayball J, Zhao Y, Li Y, Li W
Inflammation 2019 Oct;42(5):1652-1665
Inflammation 2019 Oct;42(5):1652-1665
The effect of topical ramipril and losartan cream in inhibiting scar formation.
Zheng B, Fang QQ, Wang XF, Shi BH, Zhao WY, Chen CY, Zhang MX, Zhang LY, Hu YY, Shi P, Ma L, Tan WQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109394
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109394
SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition.
Liu ZH, Zhang Y, Wang X, Fan XF, Zhang Y, Li X, Gong YS, Han LP
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109227
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109227
Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection.
Chen TT, Peng S, Wang Y, Hu Y, Shen Y, Xu Y, Yin J, Liu C, Cao J
Biomolecules 2019 Oct 25;9(11)
Biomolecules 2019 Oct 25;9(11)
Role of CCR2 in the Development of Streptozotocin-Treated Diabetic Cardiomyopathy.
Tan X, Hu L, Shu Z, Chen L, Li X, Du M, Sun D, Mao X, Deng S, Huang K, Zhang F
Diabetes 2019 Nov;68(11):2063-2073
Diabetes 2019 Nov;68(11):2063-2073
Long non-coding RNA TUG1 promotes airway remodelling by suppressing the miR-145-5p/DUSP6 axis in cigarette smoke-induced COPD.
Gu W, Yuan Y, Wang L, Yang H, Li S, Tang Z, Li Q
Journal of cellular and molecular medicine 2019 Nov;23(11):7200-7209
Journal of cellular and molecular medicine 2019 Nov;23(11):7200-7209
Sapylin (OK-432) alters inflammation and angiogenesis in vivo and vitro.
Kong D, Zhang D, Cui Q, Wang K, Tang J, Liu Z, Wu G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 May;113:108706
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 May;113:108706
Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats.
Gao J, Guo Y, Chen Y, Zhou J, Liu Y, Su P
Gene 2019 May 20;697:11-18
Gene 2019 May 20;697:11-18
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
Yu Z, Jv Y, Cai L, Tian X, Huo X, Wang C, Zhang B, Sun C, Ning J, Feng L, Zhang H, Ma X
Toxicology and applied pharmacology 2019 May 15;371:63-73
Toxicology and applied pharmacology 2019 May 15;371:63-73
miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7.
Wang M, Xiong L, Jiang LJ, Lu YZ, Liu F, Song LJ, Xiang F, He XL, Yu F, Shuai SY, Ma WL, Ye H
EBioMedicine 2019 Mar;41:670-682
EBioMedicine 2019 Mar;41:670-682
Diminished membrane recruitment of Akt is instrumental in alcohol-associated osteopenia via the PTEN/Akt/GSK-3β/β-catenin axis.
Chen YX, Zhu DY, Gao J, Xu ZL, Tao SC, Yin WJ, Zhang YL, Gao YS, Zhang CQ
The FEBS journal 2019 Mar;286(6):1101-1119
The FEBS journal 2019 Mar;286(6):1101-1119
Toxicity Effects of Methylene Blue on Rat Intervertebral Disc Annulus Fibrosus Cells.
Zhang L, Liu Y, Huang Z, Nan L, Wang F, Zhou S, Wang J, Feng X
Pain physician 2019 Mar;22(2):155-164
Pain physician 2019 Mar;22(2):155-164
Citric acid enhances the physical properties, cytocompatibility and osteogenesis of magnesium calcium phosphate cement.
Wang S, Xu C, Yu S, Wu X, Jie Z, Dai H
Journal of the mechanical behavior of biomedical materials 2019 Jun;94:42-50
Journal of the mechanical behavior of biomedical materials 2019 Jun;94:42-50
Aloe-Emodin Ameliorates Renal Fibrosis Via Inhibiting PI3K/Akt/mTOR Signaling Pathway In Vivo and In Vitro.
Dou F, Liu Y, Liu L, Wang J, Sun T, Mu F, Guo Q, Guo C, Jia N, Liu W, Ding Y, Wen A
Rejuvenation research 2019 Jun;22(3):218-229
Rejuvenation research 2019 Jun;22(3):218-229
miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal cells in rats.
Liu H, Dong Y, Feng X, Li L, Jiao Y, Bai S, Feng Z, Yu H, Li X, Zhao Y
Stem cell research & therapy 2019 Jun 18;10(1):180
Stem cell research & therapy 2019 Jun 18;10(1):180
Induction of Fibrosis and Autophagy in Kidney Cells by Vinyl Chloride.
Hsu YH, Chuang HC, Lee YH, Lin YF, Chiu YJ, Wang YL, Wu MS, Chiu HW
Cells 2019 Jun 17;8(6)
Cells 2019 Jun 17;8(6)
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
Shi A, Heinayati A, Bao D, Liu H, Ding X, Tong X, Wang L, Wang B, Qin H
Stem cell research & therapy 2019 Jun 13;10(1):172
Stem cell research & therapy 2019 Jun 13;10(1):172
Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.
Wang T, Fu X, Jin T, Zhang L, Liu B, Wu Y, Xu F, Wang X, Ye K, Zhang W, Ye L
EBioMedicine 2019 Jul;45:168-180
EBioMedicine 2019 Jul;45:168-180
Eliciting α7-nAChR exerts cardioprotective effects on ischemic cardiomyopathy via activation of AMPK signalling.
Lin ZH, Li YC, Wu SJ, Zheng C, Lin YZ, Lian H, Lin WQ, Lin JF
Journal of cellular and molecular medicine 2019 Jul;23(7):4746-4758
Journal of cellular and molecular medicine 2019 Jul;23(7):4746-4758
HBOA ameliorates CCl4-incuded liver fibrosis through inhibiting TGF-β1/Smads, NF-κB and ERK signaling pathways.
Sun X, Huang X, Zhu X, Liu L, Mo S, Wang H, Wei X, Lu S, Bai F, Wang D, Lin X, Lin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108901
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108901
LncRNA PFAR contributes to fibrogenesis in lung fibroblasts through competitively binding to miR-15a.
Sun J, Su W, Zhao X, Shan T, Jin T, Guo Y, Li C, Li R, Zhou Y, Shan H, Sun X, Liang H
Bioscience reports 2019 Jul 31;39(7)
Bioscience reports 2019 Jul 31;39(7)
Psoralen attenuates bleomycin-induced pulmonary fibrosis in mice through inhibiting myofibroblast activation and collagen deposition.
Du MY, Duan JX, Zhang CY, Yang HH, Guan XX, Zhong WJ, Liu YZ, Li ZM, Cheng YR, Zhou Y, Guan CX
Cell biology international 2019 Jul 22;
Cell biology international 2019 Jul 22;
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
Yang Y, Chen S, Tao L, Gan S, Luo H, Xu Y, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 20;25:5375-5388
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 20;25:5375-5388
Role of synovium-derived fibrous cartilage in temporomandibular joint synovial chondromatosis.
Li Y, Feng Y, Cao P, Ke J, Fang W, Cai H, Deng M, Long X
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Jan;48(1):79-86
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Jan;48(1):79-86
Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin.
Liu T, Xu L, Wang C, Chen K, Xia Y, Li J, Li S, Wu L, Feng J, Xu S, Wang W, Lu X, Fan X, Mo W, Zhou Y, Zhao Y, Guo C
Journal of gastroenterology and hepatology 2019 Jan;34(1):263-276
Journal of gastroenterology and hepatology 2019 Jan;34(1):263-276
Gene-targeted deletion in mice of the Ets-1 transcription factor, a candidate gene in the Jacobsen syndrome kidney "critical region," causes abnormal kidney development.
Ye M, Xu L, Fu M, Chen D, Mattina T, Zufardi O, Rossi E, Bush KT, Nigam SK, Grossfeld P
American journal of medical genetics. Part A 2019 Jan;179(1):71-77
American journal of medical genetics. Part A 2019 Jan;179(1):71-77
Neutralization of IL-18 by IL-18 binding protein ameliorates bleomycin-induced pulmonary fibrosis via inhibition of epithelial-mesenchymal transition.
Zhang LM, Zhang Y, Fei C, Zhang J, Wang L, Yi ZW, Gao G
Biochemical and biophysical research communications 2019 Jan 8;508(2):660-666
Biochemical and biophysical research communications 2019 Jan 8;508(2):660-666
Electrophoretic Deposition of Bioadaptive Drug Delivery Coatings on Magnesium Alloy for Bone Repair.
Qi H, Heise S, Zhou J, Schuhladen K, Yang Y, Cui N, Dong R, Virtanen S, Chen Q, Boccaccini AR, Lu T
ACS applied materials & interfaces 2019 Feb 27;11(8):8625-8634
ACS applied materials & interfaces 2019 Feb 27;11(8):8625-8634
Involvement of serum amyloid A1 in the rupture of fetal membranes through induction of collagen I degradation.
Wang WS, Li WJ, Wang YW, Wang LY, Mi YB, Lu JW, Lu Y, Zhang CY, Sun K
Clinical science (London, England : 1979) 2019 Feb 14;133(3):515-530
Clinical science (London, England : 1979) 2019 Feb 14;133(3):515-530
A Novel Tissue-Engineered Corneal Stromal Equivalent Based on Amniotic Membrane and Keratocytes.
Che X, Wu H, Jia C, Sun H, Ou S, Wang J, Jeyalatha MV, He X, Yu J, Zuo C, Liu Z, Li W
Investigative ophthalmology & visual science 2019 Feb 1;60(2):517-527
Investigative ophthalmology & visual science 2019 Feb 1;60(2):517-527
Resveratrol Attenuates Pressure Overload-Induced Cardiac Fibrosis and Diastolic Dysfunction via PTEN/AKT/Smad2/3 and NF-κB Signaling Pathways.
Zou LX, Chen C, Yan X, Lin QY, Fang J, Li PB, Han X, Wang QS, Guo SB, Li HH, Zhang YL
Molecular nutrition & food research 2019 Dec;63(24):e1900418
Molecular nutrition & food research 2019 Dec;63(24):e1900418
Paeonol prevents IL-1β-induced inflammatory response and degradation of type II collagen in human primary chondrocytes.
Wang Q, Xu X, Kang Z, Zhang Z, Li Y
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):2139-2145
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):2139-2145
Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway.
Yang R, Jia Q, Ma SF, Wang Y, Mehmood S, Chen Y
International journal of molecular medicine 2019 Aug;44(2):549-558
International journal of molecular medicine 2019 Aug;44(2):549-558
High cholesterol inhibits tendon-related gene expressions in tendon-derived stem cells through reactive oxygen species-activated nuclear factor-κB signaling.
Li K, Deng G, Deng Y, Chen S, Wu H, Cheng C, Zhang X, Yu B, Zhang K
Journal of cellular physiology 2019 Aug;234(10):18017-18028
Journal of cellular physiology 2019 Aug;234(10):18017-18028
LncRNA PCFL promotes cardiac fibrosis via miR-378/GRB2 pathway following myocardial infarction.
Sun F, Zhuang Y, Zhu H, Wu H, Li D, Zhan L, Yang W, Yuan Y, Xie Y, Yang S, Luo S, Jiang W, Zhang J, Pan Z, Lu Y
Journal of molecular and cellular cardiology 2019 Aug;133:188-198
Journal of molecular and cellular cardiology 2019 Aug;133:188-198
IMM-H007 improves heart function via reducing cardiac fibrosis.
Ge W, Zhang W, Gao R, Li B, Zhu H, Wang J
European journal of pharmacology 2019 Aug 15;857:172442
European journal of pharmacology 2019 Aug 15;857:172442
Empagliflozin prevents cardiomyopathy via sGC-cGMP-PKG pathway in type 2 diabetes mice.
Xue M, Li T, Wang Y, Chang Y, Cheng Y, Lu Y, Liu X, Xu L, Li X, Yu X, Sun B, Chen L
Clinical science (London, England : 1979) 2019 Aug 15;133(15):1705-1720
Clinical science (London, England : 1979) 2019 Aug 15;133(15):1705-1720
Calhex231 Alleviates High Glucose-Induced Myocardial Fibrosis via Inhibiting Itch-Ubiquitin Proteasome Pathway in Vitro.
Yuan H, Xu J, Xu X, Gao T, Wang Y, Fan Y, Hu J, Shao Y, Zhao B, Li H, Sun J, Xu C
Biological & pharmaceutical bulletin 2019 Aug 1;42(8):1337-1344
Biological & pharmaceutical bulletin 2019 Aug 1;42(8):1337-1344
Liraglutide prevents β-cell apoptosis via inactivation of NOX2 and its related signaling pathway.
Ding M, Fang QH, Cui YT, Shen QL, Liu Q, Wang PH, Yu DM, Li CJ
Journal of diabetes and its complications 2019 Apr;33(4):267-277
Journal of diabetes and its complications 2019 Apr;33(4):267-277
Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction.
Zhao J, Meng M, Zhang J, Li L, Zhu X, Zhang L, Wang C, Gao M
Molecular medicine reports 2019 Apr;19(4):3168-3178
Molecular medicine reports 2019 Apr;19(4):3168-3178
The inhibitory effects of COL1A2 on colorectal cancer cell proliferation, migration, and invasion.
Yu Y, Liu D, Liu Z, Li S, Ge Y, Sun W, Liu B
Journal of Cancer 2018;9(16):2953-2962
Journal of Cancer 2018;9(16):2953-2962
Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway.
Zhu J, Wang R, Xu T, Zhang S, Zhao Y, Li Z, Wang C, Zhou J, Gao D, Hu Y, Tian X, Yao J
Frontiers in pharmacology 2018;9:1277
Frontiers in pharmacology 2018;9:1277
LncRNA PFL contributes to cardiac fibrosis by acting as a competing endogenous RNA of let-7d.
Liang H, Pan Z, Zhao X, Liu L, Sun J, Su X, Xu C, Zhou Y, Zhao D, Xu B, Li X, Yang B, Lu Y, Shan H
Theranostics 2018;8(4):1180-1194
Theranostics 2018;8(4):1180-1194
Fibronectin Type III Domain-Containing 5 Attenuates Liver Fibrosis Via Inhibition of Hepatic Stellate Cell Activation.
Zhou B, Ling L, Zhang F, Liu TY, Zhou H, Qi XH, Chen Q, Li YH, Kang YM, Zhu GQ
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(1):227-236
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(1):227-236
Annexin A1 is elevated in patients with COPD and affects lung fibroblast function.
Lai T, Li Y, Mai Z, Wen X, Lv Y, Xie Z, Lv Q, Chen M, Wu D, Wu B
International journal of chronic obstructive pulmonary disease 2018;13:473-486
International journal of chronic obstructive pulmonary disease 2018;13:473-486
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Wang Q, Zang W, Han L, Yang L, Ye S, Ouyang J, Zhang C, Bi Y, Zhang C, Bian H
Chinese medicine 2018;13:17
Chinese medicine 2018;13:17
A novel bioscaffold with naturally-occurring extracellular matrix promotes hepatocyte survival and vessel patency in mouse models of heterologous transplantation.
Yang W, Chen Q, Xia R, Zhang Y, Shuai L, Lai J, You X, Jiang Y, Bie P, Zhang L, Zhang H, Bai L
Biomaterials 2018 Sep;177:52-66
Biomaterials 2018 Sep;177:52-66
Interleukin-17 enhances cardiac ventricular remodeling via activating MAPK pathway in ischemic heart failure.
Chang SL, Hsiao YW, Tsai YN, Lin SF, Liu SH, Lin YJ, Lo LW, Chung FP, Chao TF, Hu YF, Tuan TC, Liao JN, Hsieh YC, Wu TJ, Higa S, Chen SA
Journal of molecular and cellular cardiology 2018 Sep;122:69-79
Journal of molecular and cellular cardiology 2018 Sep;122:69-79
MiR-455-3p suppresses renal fibrosis through repression of ROCK2 expression in diabetic nephropathy.
Wu J, Liu J, Ding Y, Zhu M, Lu K, Zhou J, Xie X, Xu Y, Shen X, Chen Y, Shao X, Zhu C
Biochemical and biophysical research communications 2018 Sep 5;503(2):977-983
Biochemical and biophysical research communications 2018 Sep 5;503(2):977-983
lncRNA PFAR Promotes Lung Fibroblast Activation and Fibrosis by Targeting miR-138 to Regulate the YAP1-Twist Axis.
Zhao X, Sun J, Chen Y, Su W, Shan H, Li Y, Wang Y, Zheng N, Shan H, Liang H
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Sep 5;26(9):2206-2217
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Sep 5;26(9):2206-2217
Octreotide attenuates hepatic fibrosis and hepatic stellate cells proliferation and activation by inhibiting Wnt/β-catenin signaling pathway, c-Myc and cyclin D1.
Zhang C, Liu XQ, Sun HN, Meng XM, Bao YW, Zhang HP, Pan FM, Zhang C
International immunopharmacology 2018 Oct;63:183-190
International immunopharmacology 2018 Oct;63:183-190
lncRNA PFAL promotes lung fibrosis through CTGF by competitively binding miR-18a.
Li X, Yu T, Shan H, Jiang H, Sun J, Zhao X, Su W, Yang L, Shan H, Liang H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Oct;32(10):5285-5297
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Oct;32(10):5285-5297
Antifibrotic Agent Pirfenidone Protects against Development of Radiation-Induced Pulmonary Fibrosis in a Murine Model.
Qin W, Liu B, Yi M, Li L, Tang Y, Wu B, Yuan X
Radiation research 2018 Oct;190(4):396-403
Radiation research 2018 Oct;190(4):396-403
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Wang C, Luo H, Xu Y, Tao L, Chang C, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
Novel formononetin-7-sal ester ameliorates pulmonary fibrosis via MEF2c signaling pathway.
Zhao X, Qu G, Song C, Li R, Liu W, Lv C, Song X, Zhang J, Li M
Toxicology and applied pharmacology 2018 Oct 1;356:15-24
Toxicology and applied pharmacology 2018 Oct 1;356:15-24
Emission of sulfur dioxide from polyurethane foam and respiratory health effects.
Xu W, Li J, Zhang W, Wang Z, Wu J, Ge X, Wu J, Cao Y, Xie Y, Ying D, Wang Y, Wang L, Qiao Z, Jia J
Environmental pollution (Barking, Essex : 1987) 2018 Nov;242(Pt A):90-97
Environmental pollution (Barking, Essex : 1987) 2018 Nov;242(Pt A):90-97
Thrombin induces protease-activated receptor 1 signaling and activation of human atrial fibroblasts and dabigatran prevents these effects.
Altieri P, Bertolotto M, Fabbi P, Sportelli E, Balbi M, Santini F, Brunelli C, Canepa M, Montecucco F, Ameri P
International journal of cardiology 2018 Nov 15;271:219-227
International journal of cardiology 2018 Nov 15;271:219-227
Cardioprotection of CAPE-oNO2 against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Li D, Wang X, Huang Q, Li S, Zhou Y, Li Z
Redox biology 2018 May;15:62-73
Redox biology 2018 May;15:62-73
Autophagic degradation of caveolin-1 promotes liver sinusoidal endothelial cells defenestration.
Luo X, Wang D, Zhu X, Wang G, You Y, Ning Z, Li Y, Jin S, Huang Y, Hu Y, Chen T, Meng Y, Li X
Cell death & disease 2018 May 1;9(5):576
Cell death & disease 2018 May 1;9(5):576
Notch1 regulates PTEN expression to exacerbate renal tubulointerstitial fibrosis in diabetic nephropathy by inhibiting autophagy via interactions with Hes1.
Liu X, Zhang Y, Shi M, Wang Y, Zhang F, Yan R, Liu L, Xiao Y, Guo B
Biochemical and biophysical research communications 2018 Mar 18;497(4):1110-1116
Biochemical and biophysical research communications 2018 Mar 18;497(4):1110-1116
Interleukin-6 Promotes Proliferation but Inhibits Tenogenic Differentiation via the Janus Kinase/Signal Transducers and Activators of Transcription 3 (JAK/STAT3) Pathway in Tendon-Derived Stem Cells.
Chen S, Deng G, Li K, Zheng H, Wang G, Yu B, Zhang K
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 16;24:1567-1573
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 16;24:1567-1573
Effects of nicotine on the metabolism and gene expression profile of Sprague‑Dawley rat primary osteoblasts.
Liang D, Wang KJ, Tang ZQ, Liu RH, Zeng F, Cheng MY, Lian QS, Wu HK
Molecular medicine reports 2018 Jun;17(6):8269-8281
Molecular medicine reports 2018 Jun;17(6):8269-8281
Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis.
Liu Z, Zhu P, Zhang L, Xiong B, Tao J, Guan W, Li C, Chen C, Gu J, Duanmu J, Zhang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1262-1271
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1262-1271
Taurocholic acid is an active promoting factor, not just a biomarker of progression of liver cirrhosis: evidence from a human metabolomic study and in vitro experiments.
Liu Z, Zhang Z, Huang M, Sun X, Liu B, Guo Q, Chang Q, Duan Z
BMC gastroenterology 2018 Jul 11;18(1):112
BMC gastroenterology 2018 Jul 11;18(1):112
β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.
Xu H, Li Q, Liu J, Zhu J, Li L, Wang Z, Zhang Y, Sun Y, Sun J, Wang R, Yi F
Journal of molecular medicine (Berlin, Germany) 2018 Jan;96(1):97-109
Journal of molecular medicine (Berlin, Germany) 2018 Jan;96(1):97-109
Aucubin Protects against TGFβ1-Induced Cardiac Fibroblasts Activation by Mediating the AMPKα/mTOR Signaling Pathway.
Xiao Y, Chang W, Wu QQ, Jiang XH, Duan MX, Jin YG, Tang QZ
Planta medica 2018 Jan;84(2):91-99
Planta medica 2018 Jan;84(2):91-99
COL1A2 is a Novel Biomarker to Improve Clinical Prediction in Human Gastric Cancer: Integrating Bioinformatics and Meta-Analysis.
Rong L, Huang W, Tian S, Chi X, Zhao P, Liu F
Pathology oncology research : POR 2018 Jan;24(1):129-134
Pathology oncology research : POR 2018 Jan;24(1):129-134
Losartan loaded liposomes improve the antitumor efficacy of liposomal paclitaxel modified with pH sensitive peptides by inhibition of collagen in breast cancer.
Xia T, He Q, Shi K, Wang Y, Yu Q, Zhang L, Zhang Q, Gao H, Ma L, Liu J
Pharmaceutical development and technology 2018 Jan;23(1):13-21
Pharmaceutical development and technology 2018 Jan;23(1):13-21
Regulation of pancreatic stellate cell activation by Notch3.
Song H, Zhang Y
BMC cancer 2018 Jan 5;18(1):36
BMC cancer 2018 Jan 5;18(1):36
Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling.
Zhang X, Ma ZG, Yuan YP, Xu SC, Wei WY, Song P, Kong CY, Deng W, Tang QZ
Cell death & disease 2018 Jan 24;9(2):102
Cell death & disease 2018 Jan 24;9(2):102
Nicotine Induces Progressive Properties of Lung Adenocarcinoma A549 Cells by Inhibiting Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression and Plasma Membrane Localization.
Li H, Ma N, Wang J, Wang Y, Yuan C, Wu J, Luo M, Yang J, Chen J, Shi J, Liu X
Technology in cancer research & treatment 2018 Jan 1;17:1533033818809984
Technology in cancer research & treatment 2018 Jan 1;17:1533033818809984
Crosslinking Enzyme Lysyl Oxidase Modulates Scleral Remodeling in Form-Deprivation Myopia.
Yuan Y, Li M, Chen Q, Me R, Yu Y, Gu Q, Shi G, Ke B
Current eye research 2018 Feb;43(2):200-207
Current eye research 2018 Feb;43(2):200-207
Role of Gut-Derived Endotoxin on Type I Collagen Production in the Rat Pancreas After Chronic Alcohol Exposure.
Li H, Xiu M, Wang S, Brigstock DR, Sun L, Qu L, Gao R
Alcoholism, clinical and experimental research 2018 Feb;42(2):306-314
Alcoholism, clinical and experimental research 2018 Feb;42(2):306-314
Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis.
Wu J, Xing C, Zhang L, Mao H, Chen X, Liang M, Wang F, Ren H, Cui H, Jiang A, Wang Z, Zou M, Ji Y
Journal of cellular and molecular medicine 2018 Feb;22(2):1190-1201
Journal of cellular and molecular medicine 2018 Feb;22(2):1190-1201
Toxoplasma gondii GRA15II effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica.
Xie Y, Wen H, Yan K, Wang S, Wang X, Chen J, Li Y, Xu Y, Zhong Z, Shen J, Chu D
Cellular & molecular immunology 2018 Feb;15(2):120-134
Cellular & molecular immunology 2018 Feb;15(2):120-134
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis.
Zhao H, Wang Z, Tang F, Zhao Y, Feng D, Li Y, Hu Y, Wang C, Zhou J, Tian X, Yao J
Pharmacological research 2018 Feb;128:327-337
Pharmacological research 2018 Feb;128:327-337
Metformin attenuates motility, contraction, and fibrogenic response of hepatic stellate cells in vivo and in vitro by activating AMP-activated protein kinase.
Li Z, Ding Q, Ling LP, Wu Y, Meng DX, Li X, Zhang CQ
World journal of gastroenterology 2018 Feb 21;24(7):819-832
World journal of gastroenterology 2018 Feb 21;24(7):819-832
Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway.
Xiao Y, Ye J, Zhou Y, Huang J, Liu X, Huang B, Zhu L, Wu B, Zhang G, Cai Y
Archives of biochemistry and biophysics 2018 Feb 15;640:37-46
Archives of biochemistry and biophysics 2018 Feb 15;640:37-46
Interleukin‑10 promotes proliferation and migration, and inhibits tendon differentiation via the JAK/Stat3 pathway in tendon‑derived stem cells in vitro.
Deng G, Li K, Chen S, Chen P, Zheng H, Yu B, Zhang K
Molecular medicine reports 2018 Dec;18(6):5044-5052
Molecular medicine reports 2018 Dec;18(6):5044-5052
CAPE-pNO2 attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Fan L, Xiao Q, Zhang L, Wang X, Huang Q, Li S, Zhao X, Li Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1640-1650
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1640-1650
ClC-3 chloride channels are involved in estradiol regulation of bone formation by MC3T3-E1 osteoblasts.
Deng Z, Li W, Xu J, Yu M, Li D, Tan Q, Wang D, Chen L, Wang L
Journal of cellular biochemistry 2018 Dec 2;
Journal of cellular biochemistry 2018 Dec 2;
Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem.
Han X, Li Y, Xu Y, Zhao X, Zhang Y, Yang X, Wang Y, Zhao R, Anderson GJ, Zhao Y, Nie G
Nature communications 2018 Aug 23;9(1):3390
Nature communications 2018 Aug 23;9(1):3390
Effect of Polyhydroxybutyrate/Chitosan/Bioglass nanofiber scaffold on proliferation and differentiation of stem cells from human exfoliated deciduous teeth into odontoblast-like cells.
Khoroushi M, Foroughi MR, Karbasi S, Hashemibeni B, Khademi AA
Materials science & engineering. C, Materials for biological applications 2018 Aug 1;89:128-139
Materials science & engineering. C, Materials for biological applications 2018 Aug 1;89:128-139
Hydrogen sulfide ameliorates aging-associated changes in the kidney.
Lee HJ, Feliers D, Barnes JL, Oh S, Choudhury GG, Diaz V, Galvan V, Strong R, Nelson J, Salmon A, Kevil CG, Kasinath BS
GeroScience 2018 Apr;40(2):163-176
GeroScience 2018 Apr;40(2):163-176
Lipopolysaccharide enhances TGF-β1 signalling pathway and rat pancreatic fibrosis.
Sun L, Xiu M, Wang S, Brigstock DR, Li H, Qu L, Gao R
Journal of cellular and molecular medicine 2018 Apr;22(4):2346-2356
Journal of cellular and molecular medicine 2018 Apr;22(4):2346-2356
Inhibition of lysyl oxidase-like 1 (LOXL1) expression arrests liver fibrosis progression in cirrhosis by reducing elastin crosslinking.
Zhao W, Yang A, Chen W, Wang P, Liu T, Cong M, Xu A, Yan X, Jia J, You H
Biochimica et biophysica acta. Molecular basis of disease 2018 Apr;1864(4 Pt A):1129-1137
Biochimica et biophysica acta. Molecular basis of disease 2018 Apr;1864(4 Pt A):1129-1137
Melatonin Protects against Lung Fibrosis by Regulating the Hippo/YAP Pathway.
Zhao X, Sun J, Su W, Shan H, Zhang B, Wang Y, Shabanova A, Shan H, Liang H
International journal of molecular sciences 2018 Apr 9;19(4)
International journal of molecular sciences 2018 Apr 9;19(4)
Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.
Sun D, Liu Y, Wang H, Deng F, Zhang Y, Zhao S, Ma X, Wu H, Sun G
International journal of biological macromolecules 2018 Apr 1;109:1154-1163
International journal of biological macromolecules 2018 Apr 1;109:1154-1163
The Protective Effect of Cordycepin On Alcohol-Induced Osteonecrosis of the Femoral Head.
Chen YX, Zhu DY, Xu ZL, Yin JH, Yu XW, Mei J, Gao YS, Zhang CQ
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(6):2391-2403
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(6):2391-2403
Far-infrared suppresses skin photoaging in ultraviolet B-exposed fibroblasts and hairless mice.
Chiu HW, Chen CH, Chen YJ, Hsu YH
PloS one 2017;12(3):e0174042
PloS one 2017;12(3):e0174042
Galectin-3 mediates pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension.
Luo H, Liu B, Zhao L, He J, Li T, Zha L, Li X, Qi Q, Liu Y, Yu Z
Journal of the American Society of Hypertension : JASH 2017 Oct;11(10):673-683.e3
Journal of the American Society of Hypertension : JASH 2017 Oct;11(10):673-683.e3
High doses of baicalin induces kidney injury and fibrosis through regulating TGF-β/Smad signaling pathway.
Cai Y, Ma W, Xiao Y, Wu B, Li X, Liu F, Qiu J, Zhang G
Toxicology and applied pharmacology 2017 Oct 15;333:1-9
Toxicology and applied pharmacology 2017 Oct 15;333:1-9
MicroRNA-133 overexpression promotes the therapeutic efficacy of mesenchymal stem cells on acute myocardial infarction.
Chen Y, Zhao Y, Chen W, Xie L, Zhao ZA, Yang J, Chen Y, Lei W, Shen Z
Stem cell research & therapy 2017 Nov 25;8(1):268
Stem cell research & therapy 2017 Nov 25;8(1):268
The protective effect of PFTα on alcohol-induced osteonecrosis of the femoral head.
Chen YX, Zhu DY, Yin JH, Yin WJ, Zhang YL, Ding H, Yu XW, Mei J, Gao YS, Zhang CQ
Oncotarget 2017 Nov 21;8(59):100691-100707
Oncotarget 2017 Nov 21;8(59):100691-100707
The effects of artocarpin on wound healing: in vitro and in vivo studies.
Yeh CJ, Chen CC, Leu YL, Lin MW, Chiu MM, Wang SH
Scientific reports 2017 Nov 15;7(1):15599
Scientific reports 2017 Nov 15;7(1):15599
Bcl-3 is a novel biomarker of renal fibrosis in chronic kidney disease.
Chen R, Wang L, Liu S, Chen X, Hu Y, Liu H, Zhang H, Jiang Y, Wang Q, Ye D, Li L, Liu D, Pan X, Wei L, Li X, Zhang X
Oncotarget 2017 Nov 14;8(57):97206-97216
Oncotarget 2017 Nov 14;8(57):97206-97216
Synthesis of the novel PARP-1 inhibitor AG-690/11026014 and its protective effects on angiotensin II-induced mouse cardiac remodeling.
Feng GS, Zhu CG, Li ZM, Wang PX, Huang Y, Liu M, He P, Lou LL, Chen SR, Liu PQ
Acta pharmacologica Sinica 2017 May;38(5):638-650
Acta pharmacologica Sinica 2017 May;38(5):638-650
MgAl layered double hydroxide/chitosan porous scaffolds loaded with PFTα to promote bone regeneration.
Chen YX, Zhu R, Ke QF, Gao YS, Zhang CQ, Guo YP
Nanoscale 2017 May 25;9(20):6765-6776
Nanoscale 2017 May 25;9(20):6765-6776
Cadherin-11 modulates cell morphology and collagen synthesis in periodontal ligament cells under mechanical stress.
Feng L, Zhang Y, Kou X, Yang R, Liu D, Wang X, Song Y, Cao H, He D, Gan Y, Zhou Y
The Angle orthodontist 2017 Mar;87(2):193-199
The Angle orthodontist 2017 Mar;87(2):193-199
Activation of E-prostanoid 3 receptor in macrophages facilitates cardiac healing after myocardial infarction.
Tang J, Shen Y, Chen G, Wan Q, Wang K, Zhang J, Qin J, Liu G, Zuo S, Tao B, Yu Y, Wang J, Lazarus M, Yu Y
Nature communications 2017 Mar 3;8:14656
Nature communications 2017 Mar 3;8:14656
Evodiamine attenuates TGF-β1-induced fibroblast activation and endothelial to mesenchymal transition.
Wu QQ, Xiao Y, Jiang XH, Yuan Y, Yang Z, Chang W, Bian ZY, Tang QZ
Molecular and cellular biochemistry 2017 Jun;430(1-2):81-90
Molecular and cellular biochemistry 2017 Jun;430(1-2):81-90
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Tu J, Li W, Zhang Y, Wu X, Song Y, Kang L, Liu W, Wang K, Li S, Hua W, Yang C
Inflammation 2017 Jun;40(3):725-734
Inflammation 2017 Jun;40(3):725-734
Development of a new biodegradable operative clip made of a magnesium alloy: Evaluation of its safety and tolerability for canine cholecystectomy.
Yoshida T, Fukumoto T, Urade T, Kido M, Toyama H, Asari S, Ajiki T, Ikeo N, Mukai T, Ku Y
Surgery 2017 Jun;161(6):1553-1560
Surgery 2017 Jun;161(6):1553-1560
Muscarinic receptor mediated signaling pathways in hepatocytes from CCL4 - induced liver fibrotic rat.
Luo L, Xi C, Xu T, Zhang G, Qun E, Zhang W
European journal of pharmacology 2017 Jul 15;807:109-116
European journal of pharmacology 2017 Jul 15;807:109-116
Expression of muscarinic acetylcholine receptors in hepatocytes from rat fibrotic liver.
Luo L, Xu T, Wang P, Mao L, Xi C, Huang J, Zhang W
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 2017 Feb;69(2):73-81
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 2017 Feb;69(2):73-81
Ascorbate starvation alters endoplasmic reticulum-resident enzymes in cardiac fibroblasts, priming them for increased procollagen secretion.
Cowling RT, Park JI, Sotimehin AE, Greenberg BH
Journal of molecular and cellular cardiology 2017 Dec;113:1-8
Journal of molecular and cellular cardiology 2017 Dec;113:1-8
Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.
Sang L, Wang XM, Xu DY, Sang LX, Han Y, Jiang LY
World journal of gastroenterology 2017 Dec 21;23(47):8334-8344
World journal of gastroenterology 2017 Dec 21;23(47):8334-8344
Relaxin alleviates TGFβ1-induced cardiac fibrosis via inhibition of Stat3-dependent autophagy.
Yuan Y, Zhang Y, Han X, Li Y, Zhao X, Sheng L, Li Y
Biochemical and biophysical research communications 2017 Dec 2;493(4):1601-1607
Biochemical and biophysical research communications 2017 Dec 2;493(4):1601-1607
Hepatitis B virus X protein promotes the development of liver fibrosis and hepatoma through downregulation of miR-30e targeting P4HA2 mRNA.
Feng GX, Li J, Yang Z, Zhang SQ, Liu YX, Zhang WY, Ye LH, Zhang XD
Oncogene 2017 Dec 14;36(50):6895-6905
Oncogene 2017 Dec 14;36(50):6895-6905
Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.
Wu L, Zhang Q, Mo W, Feng J, Li S, Li J, Liu T, Xu S, Wang W, Lu X, Yu Q, Chen K, Xia Y, Lu J, Xu L, Zhou Y, Fan X, Guo C
Scientific reports 2017 Aug 24;7(1):9289
Scientific reports 2017 Aug 24;7(1):9289
Exogenous H2S modulates mitochondrial fusion-fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state.
Sun A, Wang Y, Liu J, Yu X, Sun Y, Yang F, Dong S, Wu J, Zhao Y, Xu C, Lu F, Zhang W
Cell & bioscience 2016;6:36
Cell & bioscience 2016;6:36
Sonodynamic Therapy Inhibits Fibrogenesis in Rat Cardiac Fibroblasts Induced by TGF-β1.
Guo Y, Dong Z, Shi Y, Wang W, Wang L, Sun J, Sun X, Tian Z, Yao J, Li Z, Cheng J, Tian Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):579-588
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):579-588
Mixed Aqueous Extract of Salvia Miltiorrhiza Reduces Blood Pressure through Inhibition of Vascular Remodelling and Oxidative Stress in Spontaneously Hypertensive Rats.
Zhang J, An SJ, Fu JQ, Liu P, Shao TM, Li M, Li X, Jiao Z, Chai XQ
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(1-2):347-360
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(1-2):347-360
Expression of Wnt/β-Catenin Signaling Pathway and Its Regulatory Role in Type I Collagen with TGF-β1 in Scleral Fibroblasts from an Experimentally Induced Myopia Guinea Pig Model.
Li M, Yuan Y, Chen Q, Me R, Gu Q, Yu Y, Sheng M, Ke B
Journal of ophthalmology 2016;2016:5126560
Journal of ophthalmology 2016;2016:5126560
Tetramethylpyrazine Attenuates Transdifferentiation of TGF-β2-Treated Human Tenon's Fibroblasts.
Cai X, Yang Y, Chen P, Ye Y, Liu X, Wu K, Yu M
Investigative ophthalmology & visual science 2016 Sep 1;57(11):4740-8
Investigative ophthalmology & visual science 2016 Sep 1;57(11):4740-8
MAD2B promotes tubular epithelial-to-mesenchymal transition and renal tubulointerstitial fibrosis via Skp2.
Tang H, Fan D, Lei CT, Ye C, Gao P, Chen S, Meng XF, Su H, Zhang C
Journal of molecular medicine (Berlin, Germany) 2016 Nov;94(11):1297-1307
Journal of molecular medicine (Berlin, Germany) 2016 Nov;94(11):1297-1307
Store-Operated Ca2+ Entry (SOCE) contributes to angiotensin II-induced cardiac fibrosis in cardiac fibroblasts.
Zhang B, Jiang J, Yue Z, Liu S, Ma Y, Yu N, Gao Y, Sun S, Chen S, Liu P
Journal of pharmacological sciences 2016 Nov;132(3):171-180
Journal of pharmacological sciences 2016 Nov;132(3):171-180
PPAR-γ is involved in the protective effect of 2,3,4',5-tetrahydroxystilbene-2-O-beta-D-glucoside against cardiac fibrosis in pressure-overloaded rats.
Peng Y, Zeng Y, Xu J, Huang XL, Zhang W, Xu XL
European journal of pharmacology 2016 Nov 15;791:105-114
European journal of pharmacology 2016 Nov 15;791:105-114
Deletion of interleukin-6 alleviated interstitial fibrosis in streptozotocin-induced diabetic cardiomyopathy of mice through affecting TGFβ1 and miR-29 pathways.
Zhang Y, Wang JH, Zhang YY, Wang YZ, Wang J, Zhao Y, Jin XX, Xue GL, Li PH, Sun YL, Huang QH, Song XT, Zhang ZR, Gao X, Yang BF, Du ZM, Pan ZW
Scientific reports 2016 Mar 14;6:23010
Scientific reports 2016 Mar 14;6:23010
miR-26a suppresses EMT by disrupting the Lin28B/let-7d axis: potential cross-talks among miRNAs in IPF.
Liang H, Liu S, Chen Y, Bai X, Liu L, Dong Y, Hu M, Su X, Chen Y, Huangfu L, Li X, Gu Y, Shan H
Journal of molecular medicine (Berlin, Germany) 2016 Jun;94(6):655-65
Journal of molecular medicine (Berlin, Germany) 2016 Jun;94(6):655-65
Increased expression of Talin1 in the eutopic and ectopic endometria of women with adenomyosis.
Jiang J, Sun A, Wang Y, Deng Y
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2016 Jun;32(6):469-72
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2016 Jun;32(6):469-72
A dual strategy to improve the penetration and treatment of breast cancer by combining shrinking nanoparticles with collagen depletion by losartan.
Cun X, Ruan S, Chen J, Zhang L, Li J, He Q, Gao H
Acta biomaterialia 2016 Feb;31:186-196
Acta biomaterialia 2016 Feb;31:186-196
An Ultra-thin Amniotic Membrane as Carrier in Corneal Epithelium Tissue-Engineering.
Zhang L, Zou D, Li S, Wang J, Qu Y, Ou S, Jia C, Li J, He H, Liu T, Yang J, Chen Y, Liu Z, Li W
Scientific reports 2016 Feb 15;6:21021
Scientific reports 2016 Feb 15;6:21021
IL-27 attenuates the TGF-β1-induced proliferation, differentiation and collagen synthesis in lung fibroblasts.
Dong Z, Zhao X, Tai W, Lei W, Wang Y, Li Z, Zhang T
Life sciences 2016 Feb 1;146:24-33
Life sciences 2016 Feb 1;146:24-33
Protective effects of triptolide on TLR4 mediated autoimmune and inflammatory response induced myocardial fibrosis in diabetic cardiomyopathy.
Guo X, Xue M, Li CJ, Yang W, Wang SS, Ma ZJ, Zhang XN, Wang XY, Zhao R, Chang BC, Chen LM
Journal of ethnopharmacology 2016 Dec 4;193:333-344
Journal of ethnopharmacology 2016 Dec 4;193:333-344
A fundamental study on the dynamics of multiple biomarkers in mouse excisional wounds for wound age estimation.
Wang LL, Zhao R, Liu CS, Liu M, Li SS, Li JY, Jiang SK, Zhang M, Tian ZL, Wang M, Zhang MZ, Guan DW
Journal of forensic and legal medicine 2016 Apr;39:138-46
Journal of forensic and legal medicine 2016 Apr;39:138-46
Ursolic acid attenuates diabetic mesangial cell injury through the up-regulation of autophagy via miRNA-21/PTEN/Akt/mTOR suppression.
Lu X, Fan Q, Xu L, Li L, Yue Y, Xu Y, Su Y, Zhang D, Wang L
PloS one 2015;10(2):e0117400
PloS one 2015;10(2):e0117400
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
Mao Y, Zhang S, Yu F, Li H, Guo C, Fan X
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
High Tumor Penetration of Paclitaxel Loaded pH Sensitive Cleavable Liposomes by Depletion of Tumor Collagen I in Breast Cancer.
Zhang L, Wang Y, Yang Y, Liu Y, Ruan S, Zhang Q, Tai X, Chen J, Xia T, Qiu Y, Gao H, He Q
ACS applied materials & interfaces 2015 May 13;7(18):9691-701
ACS applied materials & interfaces 2015 May 13;7(18):9691-701
Establishing principles of macromolecular crowding for in vitro fibrosis research of the vocal fold lamina propria.
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The Laryngoscope 2015 Jun;125(6):E203-9
The Laryngoscope 2015 Jun;125(6):E203-9
High doses of (-)-epigallocatechin-3-gallate from green tea induces cardiac fibrosis in mice.
Cai Y, He SQ, Hong HQ, Cai YP, Zhao L, Zhang M
Biotechnology letters 2015 Dec;37(12):2371-7
Biotechnology letters 2015 Dec;37(12):2371-7
Identification of genetic loci associated with primary angle-closure glaucoma in the basset hound.
Ahram DF, Cook AC, Kecova H, Grozdanic SD, Kuehn MH
Molecular vision 2014;20:497-510
Molecular vision 2014;20:497-510
Keratocytes create stromal spaces to promote corneal neovascularization via MMP13 expression.
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Investigative ophthalmology & visual science 2014 Sep 4;55(10):6691-703
Investigative ophthalmology & visual science 2014 Sep 4;55(10):6691-703
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Journal of biomedical materials research. Part A 2014 Nov;102(11):4151-60
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Journal of molecular endocrinology 2014 Apr;52(2):111-20
Journal of molecular endocrinology 2014 Apr;52(2):111-20
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Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced cardiac hypertrophy and fibrosis in vivo.
Yang J, Zhu HH, Chen GP, Ye Y, Zhao CZ, Mou Y, Hu SJ
The international journal of biochemistry & cell biology 2013 Mar;45(3):657-66
The international journal of biochemistry & cell biology 2013 Mar;45(3):657-66
The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2- and Akt-dependent mechanism.
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Attenuating effect of Fufang Xueshuantong Capsule on kidney function in diabetic nephropathy model.
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Journal of natural medicines 2013 Jan;67(1):86-97
Journal of natural medicines 2013 Jan;67(1):86-97
Molecular events in matrix protein metabolism in the aging kidney.
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Aging cell 2012 Dec;11(6):1065-73
Aging cell 2012 Dec;11(6):1065-73
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human kidney tissue were subjected to SDS PAGE followed by western blot with 14695-1-AP(COL1A2 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skin cancer using 14695-1-AP(COL1A2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Collagen Type I antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Collagen Type I. This antibody recognizes human, mouse antigen. The Collagen Type I antibody has been validated for the following applications: ELISA, WB, IHC analysis.