GTX100689

antibody from GeneTex

Targeting: TOP2A TOP2

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

GTX100689

Provider

GeneTex

Proper citation

GeneTex Cat#GTX100689, RRID:AB_1952336

Product name

Topoisomerase II alpha antibody [C3], C-term

Antibody type

Polyclonal

Reactivity

Human

Host

Rabbit

References

Submitted references

Systematic polypharmacology and drug repurposing via an integrated L1000-based Connectivity Map database mining.

Liu TP, Hsieh YY, Chou CJ, Yang PM
Royal Society open science 2018 Nov;5(11):181321

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Hyperactivated m-calpain affects acquisition of doxorubicin resistance in breast cancer cells.

Jeon KH, Yu HV, Kwon Y
Biochimica et biophysica acta. General subjects 2018 May;1862(5):1126-1133

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PGRMC1 contributes to doxorubicin-induced chemoresistance in MES-SA uterine sarcoma.

Lin ST, May EW, Chang JF, Hu RY, Wang LH, Chan HL
Cellular and molecular life sciences : CMLS 2015 Jun;72(12):2395-409

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Proteomic analysis of proteins responsible for the development of doxorubicin resistance in human uterine cancer cells.

Lin ST, Chou HC, Chang SJ, Chen YW, Lyu PC, Wang WC, Chang MD, Chan HL
Journal of proteomics 2012 Oct 22;75(18):5822-47

Western blot

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Sample (30 ug of whole cell lysate) A: H1299 5% SDS PAGE GTX100689 diluted at 1:3000

Immunohistochemistry

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Immunohistochemical analysis of paraffin-embedded SAS Xenograft , using Topoisomerase II alpha (GTX100689) antibody at 1:500 dilution.