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- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Immunohistochemistry [1]
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- Product number
- MA5-12433 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-TOP2A Monoclonal Antibody (Ki-S1)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- MA5-12436 targets Epithelial Specific Antigen in FACS, ICC/IF, IHC (P), and RIA applications and shows reactivity with Human and Mouse samples. The MA5-12436 immunogen is mCF-7 human breast cancer cells.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- Ki-S1
- Vial size
- 500 µL
- Concentration
- Lot Dependent
- Storage
- 4° C
Submitted references Mapping heterogeneity in patient-derived melanoma cultures by single-cell RNA-seq.
The Predictive and Prognostic Role of Topoisomerase IIα and Tissue Inhibitor of Metalloproteinases 1 Expression in Locally Advanced Breast Carcinoma of Egyptian Patients Treated With Anthracycline-based Neoadjuvant Chemotherapy.
One-Year Neoadjuvant Endocrine Therapy in Breast Cancer.
Cell cycle analysis can differentiate thin melanomas from dysplastic nevi and reveals accelerated replication in thick melanomas.
Tumor topoisomerase II alpha status and response to anthracycline-based neoadjuvant chemotherapy in breast cancer.
Does protein expression predict recurrence of benign World Health Organization grade I meningioma?
Expression of cyclin A and topoisomerase IIalpha of oligodendrogliomas is correlated with tumour grade, MIB-1 labelling index and survival.
Gerber T, Willscher E, Loeffler-Wirth H, Hopp L, Schadendorf D, Schartl M, Anderegg U, Camp G, Treutlein B, Binder H, Kunz M
Oncotarget 2017 Jan 3;8(1):846-862
Oncotarget 2017 Jan 3;8(1):846-862
The Predictive and Prognostic Role of Topoisomerase IIα and Tissue Inhibitor of Metalloproteinases 1 Expression in Locally Advanced Breast Carcinoma of Egyptian Patients Treated With Anthracycline-based Neoadjuvant Chemotherapy.
El Rebey HS, Aiad HA, Abulkheir IL, Asaad NY, El-Wahed MM, Abulkasem FM, Mahmoud SF
Applied immunohistochemistry & molecular morphology : AIMM 2016 Mar;24(3):167-78
Applied immunohistochemistry & molecular morphology : AIMM 2016 Mar;24(3):167-78
One-Year Neoadjuvant Endocrine Therapy in Breast Cancer.
Rusz O, Vörös A, Varga Z, Kelemen G, Uhercsák G, Nikolényi A, Ormándi K, Simonka Z, Kahán Z
Pathology oncology research : POR 2015 Sep;21(4):977-84
Pathology oncology research : POR 2015 Sep;21(4):977-84
Cell cycle analysis can differentiate thin melanomas from dysplastic nevi and reveals accelerated replication in thick melanomas.
Kiszner G, Wichmann B, Nemeth IB, Varga E, Meggyeshazi N, Teleki I, Balla P, Maros ME, Penksza K, Krenacs T
Virchows Archiv : an international journal of pathology 2014 May;464(5):603-12
Virchows Archiv : an international journal of pathology 2014 May;464(5):603-12
Tumor topoisomerase II alpha status and response to anthracycline-based neoadjuvant chemotherapy in breast cancer.
Nikolényi A, Sükösd F, Kaizer L, Csörgo E, Vörös A, Uhercsák G, Ormándi K, Lázár G, Thurzó L, Brodowicz T, Kahán Z
Oncology 2011;80(3-4):269-77
Oncology 2011;80(3-4):269-77
Does protein expression predict recurrence of benign World Health Organization grade I meningioma?
Kärjä V, Sandell PJ, Kauppinen T, Alafuzoff I
Human pathology 2010 Feb;41(2):199-207
Human pathology 2010 Feb;41(2):199-207
Expression of cyclin A and topoisomerase IIalpha of oligodendrogliomas is correlated with tumour grade, MIB-1 labelling index and survival.
Park SH, Suh YL
Histopathology 2003 Apr;42(4):395-402
Histopathology 2003 Apr;42(4):395-402
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Formalin-fixed, paraffin-embedded human tonsil stained with Topoisomerase II using peroxidase-conjugate and AEC chromogen. Note nuclear staining of proliferating cells.
