Antibody data
- Antibody Data
- Antigen structure
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- Product number
- DMAB6360 - Provider product page
- Provider
- Creative Diagnostics
- Proper citation
- Creative Diagnostics Cat#DMAB6360, RRID:AB_2395803
- Product name
- Anti-Complement C5b monoclonal antibody, clone IDD6c.2
- Antibody type
- Monoclonal
- Description
- Activation of the complement system plays a key role in normal inflammatory response to injury but may cause substantial injury when activated inappropriately. The complement system is activated either through the classical (antibody induced) or the alternative (microbial surface, polysacharride induced) pathway, both leading to the formation of the C5b9 complex. Fluid phase binding of the multifunctional glycoprotein S protein (vitronectin) to C5b9 leads to the formation of a cytolytically inactive complex, SC5b9, which is unable to attach to cells.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- IDD6c.2
- Vial size
- 1 ea
- Storage
- At 2-8°C one year after reconstitution.
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