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- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 15249-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- CDCA7 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CDCA7 antibody (Cat. #15249-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CDCA7-associated global aberrant DNA hypomethylation translates to localized, tissue-specific transcriptional responses.
High Expression of CDCA7 in the Prognosis of Glioma and Its Relationship with Ferroptosis and Immunity.
Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation.
Novel isatin-based hybrids as potential anti-rheumatoid arthritis drug candidates: Synthesis and biological evaluation.
TET2-BCLAF1 transcription repression complex epigenetically regulates the expression of colorectal cancer gene Ascl2 via methylation of its promoter.
Loss of ZBTB24 impairs nonhomologous end-joining and class-switch recombination in patients with ICF syndrome.
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome.
Lateral cortical Cdca7 expression levels are regulated by Pax6 and influence the production of intermediate progenitors.
Converging disease genes in ICF syndrome: ZBTB24 controls expression of CDCA7 in mammals.
Transmissible gastroenteritis virus (TGEV) infection alters the expression of cellular microRNA species that affect transcription of TGEV gene 7.
Vukic M, Chouaref J, Della Chiara V, Dogan S, Ratner F, Hogenboom JZM, Epp TA, Chawengsaksophak K, Vonk KKD, Breukel C, Ariyurek Y, San Leon Granado D, Kloet SL, Daxinger L
Science advances 2024 Feb 9;10(6):eadk3384
Science advances 2024 Feb 9;10(6):eadk3384
High Expression of CDCA7 in the Prognosis of Glioma and Its Relationship with Ferroptosis and Immunity.
Wang Y, Zhao Y, Zhang Z, Zhang J, Xu Q, Zhou X, Mao L
Genes 2023 Jul 6;14(7)
Genes 2023 Jul 6;14(7)
Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation.
Muneer A, Wang L, Xie L, Zhang F, Wu B, Mei L, Lenarcic EM, Feng EH, Song J, Xiong Y, Yu X, Wang C, Jain K, Strahl BD, Cook JG, Wan YY, Moorman NJ, Song H, Jin J, Chen X
Cell chemical biology 2023 Dec 21;30(12):1525-1541.e7
Cell chemical biology 2023 Dec 21;30(12):1525-1541.e7
Novel isatin-based hybrids as potential anti-rheumatoid arthritis drug candidates: Synthesis and biological evaluation.
Chen J, Lin X, He J, Liu J, He J, Tao C, Wang Q
Bioorganic chemistry 2022 Nov;128:106063
Bioorganic chemistry 2022 Nov;128:106063
TET2-BCLAF1 transcription repression complex epigenetically regulates the expression of colorectal cancer gene Ascl2 via methylation of its promoter.
Shang Y, Jiang T, Ran L, Hu W, Wu Y, Ye J, Peng Z, Chen L, Wang R
The Journal of biological chemistry 2022 Jul;298(7):102095
The Journal of biological chemistry 2022 Jul;298(7):102095
Loss of ZBTB24 impairs nonhomologous end-joining and class-switch recombination in patients with ICF syndrome.
Helfricht A, Thijssen PE, Rother MB, Shah RG, Du L, Takada S, Rogier M, Moritz J, IJspeert H, Stoepker C, van Ostaijen-Ten Dam MM, Heyer V, Luijsterburg MS, de Groot A, Jak R, Grootaers G, Wang J, Rao P, Vertegaal ACO, van Tol MJD, Pan-Hammarström Q, Reina-San-Martin B, Shah GM, van der Burg M, van der Maarel SM, van Attikum H
The Journal of experimental medicine 2020 Nov 2;217(11)
The Journal of experimental medicine 2020 Nov 2;217(11)
Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics.
Wang L, Muneer A, Xie L, Zhang F, Wu B, Mei L, Lenarcic EM, Feng EH, Song J, Xiong Y, Yu X, Wang C, Gheorghe C, Torralba K, Cook JG, Wan YY, Moorman NJ, Song H, Jin J, Chen X
bioRxiv : the preprint server for biology 2020 Nov 16;
bioRxiv : the preprint server for biology 2020 Nov 16;
HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome.
Jenness C, Giunta S, Müller MM, Kimura H, Muir TW, Funabiki H
Proceedings of the National Academy of Sciences of the United States of America 2018 Jan 30;115(5):E876-E885
Proceedings of the National Academy of Sciences of the United States of America 2018 Jan 30;115(5):E876-E885
Lateral cortical Cdca7 expression levels are regulated by Pax6 and influence the production of intermediate progenitors.
Huang YT, Mason JO, Price DJ
BMC neuroscience 2017 Jun 5;18(1):47
BMC neuroscience 2017 Jun 5;18(1):47
Converging disease genes in ICF syndrome: ZBTB24 controls expression of CDCA7 in mammals.
Wu H, Thijssen PE, de Klerk E, Vonk KK, Wang J, den Hamer B, Aytekin C, van der Maarel SM, Daxinger L
Human molecular genetics 2016 Sep 15;25(18):4041-4051
Human molecular genetics 2016 Sep 15;25(18):4041-4051
Transmissible gastroenteritis virus (TGEV) infection alters the expression of cellular microRNA species that affect transcription of TGEV gene 7.
Song X, Zhao X, Huang Y, Xiang H, Zhang W, Tong D
International journal of biological sciences 2015;11(8):913-22
International journal of biological sciences 2015;11(8):913-22
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Raji cells were subjected to SDS PAGE followed by western blot with 15249-1-AP( CDCA7 Antibody) at dilution of 1:200
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CDCA7 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CDCA7. This antibody recognizes human,mouse,rat antigen. The CDCA7 antibody has been validated for the following applications: ELISA, IF, WB analysis.
