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ADRB2
Adrenoceptor beta 2ADRB2R, ADRBR, B2AR, BAR
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor is also a transcription regulator of the alpha-synuclein gene, and together, both genes are believed to be associated with risk of Parkinson's Disease. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity, type 2 diabetes and cardiovascular disease. [provided by RefSeq, Oct 2019]
Top validated antibodies |
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| Proteintech Group |  13096-1-AP |
14 references | Polyclonal |
WB
EL
IHC
FC
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| antibodies-online | ABIN5862415 |
Monoclonal |
WB
EL
ICC
IHC
FC
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| LSBio | LS-C198600 |
Polyclonal |
WB
EL
ICC
IHC
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| Enzo Life Sciences | ADI-905-742-100 |
1 references | Polyclonal |
WB
EL
ICC
IHC
|
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| Invitrogen Antibodies | PA5-38403 |
2 references | Polyclonal |
WB
IHC
OA
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