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- References [21]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 14299-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14299-1-AP, RRID:AB_2110515
- Product name
- GLUD1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GLUD1 antibody (Cat. #14299-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Urea as a By-Product of Ammonia Metabolism Can Be a Potential Serum Biomarker of Hepatocellular Carcinoma.
Cytosolic GDH1 degradation restricts protein synthesis to sustain tumor cell survival following amino acid deprivation.
Pyruvate Kinase M2 Supports Muscle Progenitor Cell Proliferation but Is Dispensable for Skeletal Muscle Regeneration after Injury.
Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1.
PINCH-1 promotes Δ1-pyrroline-5-carboxylate synthase expression and contributes to proline metabolic reprogramming in lung adenocarcinoma.
Mitochondrial Metabolism behind Region-Specific Resistance to Ischemia-Reperfusion Injury in Gerbil Hippocampus. Role of PKCβII and Phosphate-Activated Glutaminase.
The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma.
Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism.
Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis.
Preventing BRCA1/ZBRK1 repressor complex binding to the GOT2 promoter results in accelerated aspartate biosynthesis and promotion of cell proliferation.
Resibufogenin suppresses colorectal cancer growth and metastasis through RIP3-mediated necroptosis.
Sirtuin5 contributes to colorectal carcinogenesis by enhancing glutaminolysis in a deglutarylation-dependent manner.
Effects of Dahuang zhechong pill on doxorubicin-resistant SMMC-7721 xenografts in mice.
Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass.
Replication of the Shrimp Virus WSSV Depends on Glutamate-Driven Anaplerosis.
Blocking glutamate carboxypeptidase II inhibits glutamate excitotoxicity and regulates immune responses in experimental autoimmune encephalomyelitis.
Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients.
Mitochondrial Sirtuin Network Reveals Dynamic SIRT3-Dependent Deacetylation in Response to Membrane Depolarization.
Differential Glutamate Metabolism in Proliferating and Quiescent Mammary Epithelial Cells.
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Cerebral level of vGlut1 is increased and level of glycine is decreased in TgSwDI mice.
Bai C, Wang H, Dong D, Li T, Yu Z, Guo J, Zhou W, Li D, Yan R, Wang L, Wang Z, Li Y, Ren L
Frontiers in cell and developmental biology 2021;9:650748
Frontiers in cell and developmental biology 2021;9:650748
Cytosolic GDH1 degradation restricts protein synthesis to sustain tumor cell survival following amino acid deprivation.
Shao J, Shi T, Yu H, Ding Y, Li L, Wang X, Wang X
The EMBO journal 2021 Oct 18;40(20):e107480
The EMBO journal 2021 Oct 18;40(20):e107480
Pyruvate Kinase M2 Supports Muscle Progenitor Cell Proliferation but Is Dispensable for Skeletal Muscle Regeneration after Injury.
Blum JE, Gheller BJ, Benvie A, Field MS, Panizza E, Vacanti NM, Berry D, Thalacker-Mercer A
The Journal of nutrition 2021 Nov 2;151(11):3313-3328
The Journal of nutrition 2021 Nov 2;151(11):3313-3328
Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1.
Tsai PY, Lee MS, Jadhav U, Naqvi I, Madha S, Adler A, Mistry M, Naumenko S, Lewis CA, Hitchcock DS, Roberts FR, DelNero P, Hank T, Honselmann KC, Morales Oyarvide V, Mino-Kenudson M, Clish CB, Shivdasani RA, Kalaany NY
Proceedings of the National Academy of Sciences of the United States of America 2021 Mar 9;118(10)
Proceedings of the National Academy of Sciences of the United States of America 2021 Mar 9;118(10)
PINCH-1 promotes Δ1-pyrroline-5-carboxylate synthase expression and contributes to proline metabolic reprogramming in lung adenocarcinoma.
Cui C, Wang J, Guo L, Wu C
Amino acids 2021 Dec;53(12):1875-1890
Amino acids 2021 Dec;53(12):1875-1890
Mitochondrial Metabolism behind Region-Specific Resistance to Ischemia-Reperfusion Injury in Gerbil Hippocampus. Role of PKCβII and Phosphate-Activated Glutaminase.
Beręsewicz-Haller M, Krupska O, Bochomulski P, Dudzik D, Chęcińska A, Hilgier W, Barbas C, Zablocki K, Zablocka B
International journal of molecular sciences 2021 Aug 7;22(16)
International journal of molecular sciences 2021 Aug 7;22(16)
The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma.
Lin Y, Jin H, Wu X, Jian Z, Zou X, Huang J, Guan R, Wei X
Aging 2020 Jul 27;12(14):14391-14405
Aging 2020 Jul 27;12(14):14391-14405
Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism.
Bott AJ, Shen J, Tonelli C, Zhan L, Sivaram N, Jiang YP, Yu X, Bhatt V, Chiles E, Zhong H, Maimouni S, Dai W, Velasquez S, Pan JA, Muthalagu N, Morton J, Anthony TG, Feng H, Lamers WH, Murphy DJ, Guo JY, Jin J, Crawford HC, Zhang L, White E, Lin RZ, Su X, Tuveson DA, Zong WX
Cell reports 2019 Oct 29;29(5):1287-1298.e6
Cell reports 2019 Oct 29;29(5):1287-1298.e6
Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis.
Li M, Chiang YL, Lyssiotis CA, Teater MR, Hong JY, Shen H, Wang L, Hu J, Jing H, Chen Z, Jain N, Duy C, Mistry SJ, Cerchietti L, Cross JR, Cantley LC, Green MR, Lin H, Melnick AM
Cancer cell 2019 Jun 10;35(6):916-931.e9
Cancer cell 2019 Jun 10;35(6):916-931.e9
Preventing BRCA1/ZBRK1 repressor complex binding to the GOT2 promoter results in accelerated aspartate biosynthesis and promotion of cell proliferation.
Hong R, Zhang W, Xia X, Zhang K, Wang Y, Wu M, Fan J, Li J, Xia W, Xu F, Chen J, Wang S, Zhan Q
Molecular oncology 2019 Apr;13(4):959-977
Molecular oncology 2019 Apr;13(4):959-977
Resibufogenin suppresses colorectal cancer growth and metastasis through RIP3-mediated necroptosis.
Han Q, Ma Y, Wang H, Dai Y, Chen C, Liu Y, Jing L, Sun X
Journal of translational medicine 2018 Jul 20;16(1):201
Journal of translational medicine 2018 Jul 20;16(1):201
Sirtuin5 contributes to colorectal carcinogenesis by enhancing glutaminolysis in a deglutarylation-dependent manner.
Wang YQ, Wang HL, Xu J, Tan J, Fu LN, Wang JL, Zou TH, Sun DF, Gao QY, Chen YX, Fang JY
Nature communications 2018 Feb 7;9(1):545
Nature communications 2018 Feb 7;9(1):545
Effects of Dahuang zhechong pill on doxorubicin-resistant SMMC-7721 xenografts in mice.
Wu L, Cao KX, Ni ZH, Li WD, Chen ZP, Cheng HB, Liu X
Journal of ethnopharmacology 2018 Aug 10;222:71-78
Journal of ethnopharmacology 2018 Aug 10;222:71-78
Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass.
Spinelli JB, Yoon H, Ringel AE, Jeanfavre S, Clish CB, Haigis MC
Science (New York, N.Y.) 2017 Nov 17;358(6365):941-946
Science (New York, N.Y.) 2017 Nov 17;358(6365):941-946
Replication of the Shrimp Virus WSSV Depends on Glutamate-Driven Anaplerosis.
Li CY, Wang YJ, Huang SW, Cheng CS, Wang HC
PloS one 2016;11(1):e0146902
PloS one 2016;11(1):e0146902
Blocking glutamate carboxypeptidase II inhibits glutamate excitotoxicity and regulates immune responses in experimental autoimmune encephalomyelitis.
Ha D, Bing SJ, Ahn G, Kim J, Cho J, Kim A, Herath KH, Yu HS, Jo SA, Cho IH, Jee Y
The FEBS journal 2016 Sep;283(18):3438-56
The FEBS journal 2016 Sep;283(18):3438-56
Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients.
Qin S, Zhou Y, Gray L, Kusebauch U, McEvoy L, Antoine DJ, Hampson L, Park KB, Campbell D, Caballero J, Glusman G, Yan X, Kim TK, Yuan Y, Wang K, Rowen L, Moritz RL, Omenn GS, Pirmohamed M, Hood L
Journal of proteome research 2016 Oct 7;15(10):3724-3740
Journal of proteome research 2016 Oct 7;15(10):3724-3740
Mitochondrial Sirtuin Network Reveals Dynamic SIRT3-Dependent Deacetylation in Response to Membrane Depolarization.
Yang W, Nagasawa K, Münch C, Xu Y, Satterstrom K, Jeong S, Hayes SD, Jedrychowski MP, Vyas FS, Zaganjor E, Guarani V, Ringel AE, Gygi SP, Harper JW, Haigis MC
Cell 2016 Nov 3;167(4):985-1000.e21
Cell 2016 Nov 3;167(4):985-1000.e21
Differential Glutamate Metabolism in Proliferating and Quiescent Mammary Epithelial Cells.
Coloff JL, Murphy JP, Braun CR, Harris IS, Shelton LM, Kami K, Gygi SP, Selfors LM, Brugge JS
Cell metabolism 2016 May 10;23(5):867-80
Cell metabolism 2016 May 10;23(5):867-80
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Sun L, Song L, Wan Q, Wu G, Li X, Wang Y, Wang J, Liu Z, Zhong X, He X, Shen S, Pan X, Li A, Wang Y, Gao P, Tang H, Zhang H
Cell research 2015 Apr;25(4):429-44
Cell research 2015 Apr;25(4):429-44
Cerebral level of vGlut1 is increased and level of glycine is decreased in TgSwDI mice.
Timmer NM, Metaxas A, van der Stelt I, Kluijtmans LA, van Berckel BN, Verbeek MM
Journal of Alzheimer's disease : JAD 2014;39(1):89-101
Journal of Alzheimer's disease : JAD 2014;39(1):89-101
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 14299-1-AP(GLUD1 antibody) at dilution of 1:3000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 14299-1-AP(GLUD1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GLUD1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GLUD1. This antibody recognizes human,mouse,rat antigen. The GLUD1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
