BS8393

antibody from Bioworld Technology, Inc
Targeting: SARS1 SARS, SERS
Provider product page for BS8393
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8393 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SARS polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human SARS.
Description
Severe acute respiratory syndrome (SARS) coronavirus, a recently emergent infectious agent, shares little homology with previously known coronaviruses with respect to its genes and encoding proteins. Following this pattern, SARS nucleocapsid protein (SARS NC) only weakly resembles analogous proteins of the coronavirus family, and thus estimations of its function prove difficult. In fact, the region encoding SARS NC and other matrix and nucleocapsid proteins more closely resembles avian coronaviruses, while phylogenetic analyses indicate a mammalian origin for the replicase protein. SARS NC expression increases the binding of transcription factors to promotor sequences of c-Fos, ATF2, CREB-1, and FosB, all components of the AP-1 signaling pathway. Other signaling pathways, e.g. the NF°ÙB pathway, are not affected, however, implying that pathway activation by SARS NC is selective, and thus possibly an important target in SARS functional studies.Most viral particles show the appearance of spike-like glycoprotein surface projections, giving rise to the virus' name, which is Latin for crown. These transmembrane spike glycoproteins protrude 20 nanometers from the surface.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SARS1 protein structure - BS8393 shown in red.