Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-BL8014 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-Lgals3 Monoclonal antibody, clone N4/49
- Antibody type
- Monoclonal
- Description
- Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
- Reactivity
- Human, Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Isotype
- IgG
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