Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- 11274-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11274-1-AP, RRID:AB_2058719
- Product name
- ASAH1 antibody
- Antibody type
- Polyclonal
- Description
- ASAH1 antibody (Cat. #11274-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease.
Hyperbaric Oxygen Treatment Ameliorates Hearing Loss and Auditory Cortex Injury in Noise Exposed Mice by Repressing Local Ceramide Accumulation.
Acid ceramidase inhibition ameliorates α-synuclein accumulation upon loss of GBA1 function.
Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis.
Doxepin Mitigates Noise-induced Neuronal Damage in Primary Auditory Cortex of Mice via Suppression of Acid Sphingomyelinase/Ceramide Pathway.
A reconstructed human epidermal keratinization culture model to characterize ceramide metabolism in the stratum corneum.
Th1 cytokines accentuate but Th2 cytokines attenuate ceramide production in the stratum corneum of human epidermal equivalents: an implication for the disrupted barrier mechanism in atopic dermatitis.
Lang J, Bohn P, Bhat H, Jastrow H, Walkenfort B, Cansiz F, Fink J, Bauer M, Olszewski D, Ramos-Nascimento A, Duhan V, Friedrich SK, Becker KA, Krawczyk A, Edwards MJ, Burchert A, Huber M, Friebus-Kardash J, Göthert JR, Hardt C, Probst HC, Schumacher F, Köhrer K, Kleuser B, Babiychuk EB, Sodeik B, Seibel J, Greber UF, Lang PA, Gulbins E, Lang KS
Nature communications 2020 Mar 12;11(1):1338
Nature communications 2020 Mar 12;11(1):1338
Hyperbaric Oxygen Treatment Ameliorates Hearing Loss and Auditory Cortex Injury in Noise Exposed Mice by Repressing Local Ceramide Accumulation.
Su YT, Guo YB, Cheng YP, Zhang X, Xie XP, Chang YM, Bao JX
International journal of molecular sciences 2019 Sep 20;20(19)
International journal of molecular sciences 2019 Sep 20;20(19)
Acid ceramidase inhibition ameliorates α-synuclein accumulation upon loss of GBA1 function.
Kim MJ, Jeon S, Burbulla LF, Krainc D
Human molecular genetics 2018 Jun 1;27(11):1972-1988
Human molecular genetics 2018 Jun 1;27(11):1972-1988
Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis.
Tang YC, Yuwen H, Wang K, Bruno PM, Bullock K, Deik A, Santaguida S, Trakala M, Pfau SJ, Zhong N, Huang T, Wang L, Clish CB, Hemann MT, Amon A
Cancer research 2017 Oct 1;77(19):5272-5286
Cancer research 2017 Oct 1;77(19):5272-5286
Doxepin Mitigates Noise-induced Neuronal Damage in Primary Auditory Cortex of Mice via Suppression of Acid Sphingomyelinase/Ceramide Pathway.
Su YT, Meng XX, Zhang X, Guo YB, Zhang HJ, Cheng YP, Xie XP, Chang YM, Bao JX
Anatomical record (Hoboken, N.J. : 2007) 2017 Dec;300(12):2220-2232
Anatomical record (Hoboken, N.J. : 2007) 2017 Dec;300(12):2220-2232
A reconstructed human epidermal keratinization culture model to characterize ceramide metabolism in the stratum corneum.
Yoshida N, Sawada E, Imokawa G
Archives of dermatological research 2012 Sep;304(7):563-77
Archives of dermatological research 2012 Sep;304(7):563-77
Th1 cytokines accentuate but Th2 cytokines attenuate ceramide production in the stratum corneum of human epidermal equivalents: an implication for the disrupted barrier mechanism in atopic dermatitis.
Sawada E, Yoshida N, Sugiura A, Imokawa G
Journal of dermatological science 2012 Oct;68(1):25-35
Journal of dermatological science 2012 Oct;68(1):25-35
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 11274-1-AP(ASAH1 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ASAH1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ASAH1. This antibody recognizes human, mouse, rat antigen. The ASAH1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.