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- Antigen structure
- References [4]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN783822 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- 16 amino acid peptide near the carboxy terminus of the Human ASAH1
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Vial size
- 0.1 mg
- Storage
- Store the antibody undiluted at 2-8°C up to three months or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Deregulation of sphingolipid metabolism in Alzheimer's disease.
Insertional mutagenesis of the mouse acid ceramidase gene leads to early embryonic lethality in homozygotes and progressive lipid storage disease in heterozygotes.
Alkaline sphingomyelinases and ceramidases of the gastrointestinal tract.
Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification Of the first molecular lesion causing Farber disease.
He X, Huang Y, Li B, Gong CX, Schuchman EH
Neurobiology of aging 2010 Mar;31(3):398-408
Neurobiology of aging 2010 Mar;31(3):398-408
Insertional mutagenesis of the mouse acid ceramidase gene leads to early embryonic lethality in homozygotes and progressive lipid storage disease in heterozygotes.
Li CM, Park JH, Simonaro CM, He X, Gordon RE, Friedman AH, Ehleiter D, Paris F, Manova K, Hepbildikler S, Fuks Z, Sandhoff K, Kolesnick R, Schuchman EH
Genomics 2002 Feb;79(2):218-24
Genomics 2002 Feb;79(2):218-24
Alkaline sphingomyelinases and ceramidases of the gastrointestinal tract.
Nilsson A, Duan RD
Chemistry and physics of lipids 1999 Nov;102(1-2):97-105
Chemistry and physics of lipids 1999 Nov;102(1-2):97-105
Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification Of the first molecular lesion causing Farber disease.
Koch J, Gärtner S, Li CM, Quintern LE, Bernardo K, Levran O, Schnabel D, Desnick RJ, Schuchman EH, Sandhoff K
The Journal of biological chemistry 1996 Dec 20;271(51):33110-5
The Journal of biological chemistry 1996 Dec 20;271(51):33110-5
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of ASAH1 in mouse heart tissue lysate with ASAH1 antibody at (A) 1 and (B) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of ASAH1 in human heart tissue with ASAH1 antibody at 2.5 ?g/ml.
