Antibody data
- Antibody Data
- Antigen structure
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- Product number
- DPABH-09918 - Provider product page
- Provider
- Creative Diagnostics
- Proper citation
- Creative Diagnostics Cat#DPABH-09918, RRID:AB_2523308
- Product name
- Rabbit Anti-Human BMP10 Polyclonal Antibody
- Antibody type
- Polyclonal
- Description
- Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Concentration
- Lot specific
- Storage
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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