AMM03007G

antibody from Leading Biology

Targeting: PDK2 PDHK2

Western blot (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

AMM03007G

Provider

Leading Biology

Product name

PDK2 Antibody

Antibody type

Monoclonal

Description

The protein encoded by this gene belongs to putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro) and CD33 plays potential key roles in the pathogenesis of Alzheimer's disease (AD)

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

3F2D7

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.