Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [2]
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- Product number
- ABIN188708 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7) antibody
- Antibody type
- Polyclonal
- Description
- Protein G purified
- Reactivity
- Human, Mouse, Rat, Canine
- Host
- Rabbit
- Vial size
- 0.1 mg
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Tryptophan hydroxylase 1 and 5-HT7 receptor preferentially expressed in triple-negative breast cancer promote cancer progression through autocrine serotonin signaling.
Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamics.
The serotonin receptor 5-HT₇R regulates the morphology and migratory properties of dendritic cells.
Expression of the spinal 5-HT7 receptor and p-ERK pathway in the carrageenan inflammatory pain of rats.
Sensitization of restraint-induced corticosterone secretion after chronic restraint in rats: involvement of 5-HT₇ receptors.
Blockade of 5-HT7 receptors reduces tactile allodynia in the rat.
Biphasic regulation of mammary epithelial resistance by serotonin through activation of multiple pathways.
Mammary gland homeostasis employs serotonergic regulation of epithelial tight junctions.
Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor.
Serotonin 5-HT7 receptors coupled to induction of interleukin-6 in human microglial MC-3 cells.
Functional expression of the serotonin 5-HT7 receptor in human glioblastoma cell lines.
Gautam J, Banskota S, Regmi SC, Ahn S, Jeon YH, Jeong H, Kim SJ, Nam TG, Jeong BS, Kim JA
Molecular cancer 2016 Nov 21;15(1):75
Molecular cancer 2016 Nov 21;15(1):75
Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamics.
Speranza L, Giuliano T, Volpicelli F, De Stefano ME, Lombardi L, Chambery A, Lacivita E, Leopoldo M, Bellenchi GC, di Porzio U, Crispino M, Perrone-Capano C
Frontiers in behavioral neuroscience 2015;9:62
Frontiers in behavioral neuroscience 2015;9:62
The serotonin receptor 5-HT₇R regulates the morphology and migratory properties of dendritic cells.
Holst K, Guseva D, Schindler S, Sixt M, Braun A, Chopra H, Pabst O, Ponimaskin E
Journal of cell science 2015 Aug 1;128(15):2866-80
Journal of cell science 2015 Aug 1;128(15):2866-80
Expression of the spinal 5-HT7 receptor and p-ERK pathway in the carrageenan inflammatory pain of rats.
Cho SY, Ki HG, Kim JM, Oh JM, Yang JH, Kim WM, Lee HG, Yoon MH, Choi JI
Korean journal of anesthesiology 2015 Apr;68(2):170-4
Korean journal of anesthesiology 2015 Apr;68(2):170-4
Sensitization of restraint-induced corticosterone secretion after chronic restraint in rats: involvement of 5-HT₇ receptors.
García-Iglesias BB, Mendoza-Garrido ME, Gutiérrez-Ospina G, Rangel-Barajas C, Noyola-Díaz M, Terrón JA
Neuropharmacology 2013 Aug;71:216-27
Neuropharmacology 2013 Aug;71:216-27
Blockade of 5-HT7 receptors reduces tactile allodynia in the rat.
Amaya-Castellanos E, Pineda-Farias JB, Castañeda-Corral G, Vidal-Cantú GC, Murbartián J, Rocha-González HI, Granados-Soto V
Pharmacology, biochemistry, and behavior 2011 Oct;99(4):591-7
Pharmacology, biochemistry, and behavior 2011 Oct;99(4):591-7
Biphasic regulation of mammary epithelial resistance by serotonin through activation of multiple pathways.
Pai VP, Horseman ND
The Journal of biological chemistry 2008 Nov 7;283(45):30901-10
The Journal of biological chemistry 2008 Nov 7;283(45):30901-10
Mammary gland homeostasis employs serotonergic regulation of epithelial tight junctions.
Stull MA, Pai V, Vomachka AJ, Marshall AM, Jacob GA, Horseman ND
Proceedings of the National Academy of Sciences of the United States of America 2007 Oct 16;104(42):16708-13
Proceedings of the National Academy of Sciences of the United States of America 2007 Oct 16;104(42):16708-13
Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor.
León-Ponte M, Ahern GP, O'Connell PJ
Blood 2007 Apr 15;109(8):3139-46
Blood 2007 Apr 15;109(8):3139-46
Serotonin 5-HT7 receptors coupled to induction of interleukin-6 in human microglial MC-3 cells.
Mahé C, Loetscher E, Dev KK, Bobirnac I, Otten U, Schoeffter P
Neuropharmacology 2005 Jul;49(1):40-7
Neuropharmacology 2005 Jul;49(1):40-7
Functional expression of the serotonin 5-HT7 receptor in human glioblastoma cell lines.
Mahé C, Bernhard M, Bobirnac I, Keser C, Loetscher E, Feuerbach D, Dev KK, Schoeffter P
British journal of pharmacology 2004 Oct;143(3):404-10
British journal of pharmacology 2004 Oct;143(3):404-10
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- Submitted by
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- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB