Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Immunohistochemistry [3]
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Validation data
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- Product number
- NBP1-46598 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-46598, RRID:AB_10009834
- Product name
- Rabbit Polyclonal 5-HT7 Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified. Specific for 5HT7R receptor.
- Reactivity
- Human, Mouse, Rat, Guinea Pig
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- LYOPH
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Creation of the 5-hydroxytryptamine receptor 7 knockout rat as a tool for cardiovascular research.
The brain-penetrant 5-HT(7) receptor agonist LP-211 reduces the sensory and affective components of neuropathic pain.
Differential responses to acute administration of a new 5-HT7-R agonist as a function of adolescent pre-treatment: phMRI and immuno-histochemical study.
Involvement of 5-HT₇ receptors in the pathogenesis of temporal lobe epilepsy.
Demireva EY, Xie H, Flood ED, Thompson JM, Seitz BM, Watts SW
Physiological genomics 2019 Jul 1;51(7):290-301
Physiological genomics 2019 Jul 1;51(7):290-301
The brain-penetrant 5-HT(7) receptor agonist LP-211 reduces the sensory and affective components of neuropathic pain.
Santello M, Bisco A, Nevian NE, Lacivita E, Leopoldo M, Nevian T
Neurobiology of disease 2017 Oct;106:214-221
Neurobiology of disease 2017 Oct;106:214-221
Differential responses to acute administration of a new 5-HT7-R agonist as a function of adolescent pre-treatment: phMRI and immuno-histochemical study.
Altabella L, Sbriccoli M, Zoratto F, Poleggi A, Vinci R, Lacivita E, Leopoldo M, Laviola G, Cardone F, Canese R, Adriani W
Frontiers in behavioral neuroscience 2014;8:427
Frontiers in behavioral neuroscience 2014;8:427
Involvement of 5-HT₇ receptors in the pathogenesis of temporal lobe epilepsy.
Yang Z, Liu X, Yin Y, Sun S, Deng X
European journal of pharmacology 2012 Jun 15;685(1-3):52-8
European journal of pharmacology 2012 Jun 15;685(1-3):52-8
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: 5HT7 Receptor Antibody [NBP1-46598] - Rat spinal cord (paraffin section) using Rabbit antibody to internal region of 5HT7R receptor (Serotonin receptor 7R): whole serum at 1 : 200 dilution incubated overnight at 4C, developed with DAB/Ni.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: 5HT7 Receptor Antibody [NBP1-46598] - Rat spinal cord (paraffin section) using Rabbit antibody to internal region of 5HT7R receptor (Serotonin receptor 7R): whole serum at 1 : 200 dilution incubated overnight at 4C, developed with DAB/Ni.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: 5HT7 Receptor Antibody [NBP1-46598] - Rat spinal cord (paraffin section) using Rabbit antibody to internal region of 5HT7R receptor (Serotonin receptor 7R): whole serum at 1 : 200 dilution incubated overnight at 4C, developed with DAB/Ni.