STON2

This gene encodes a protein which is a membrane protein involved in regulating endocytotic complexes. The protein product is described as one of the clathrin-associated sorting proteins, adaptor molecules which ensure specific proteins are internalized. The encoded protein has also been shown to participate in synaptic vesicle recycling through interaction with synaptotagmin 1 required for neurotransmission. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Description

Stonin 2

Tissue specificity

Tissue enriched (brain)

Subcell location

Nucleoli, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

14 (81260656 - 81436465)

Ensembl ID

ENSG00000140022  (ver. 103.38)

Orthologs

Mouse Ston2: ENSMUSG00000020961

UniProt

Q8WXE9

neXtProt

NX_Q8WXE9

Human splice variants
Mouse splice variants

Protein structure