Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [2]
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Validation data
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- Product number
- NB100-53791 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-53791, RRID:AB_2084690
- Product name
- Goat Polyclonal CPT1A Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. This antibody is expected to recognize both reported isoforms (NP_001867.2
- Reactivity
- Human, Mouse, Rat
- Host
- Goat
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Hypoxia training improves hepatic steatosis partly by downregulation of CB1 receptor in obese mice.
CPT1A plays a key role in the development and treatment of multiple sclerosis and experimental autoimmune encephalomyelitis.
Paracrine-endocrine FGF chimeras as potent therapeutics for metabolic diseases.
Troxerutin improves hepatic lipid homeostasis by restoring NAD(+)-depletion-mediated dysfunction of lipin 1 signaling in high-fat diet-treated mice.
A regulatory role for microRNA 33* in controlling lipid metabolism gene expression.
Dysregulation of hepatic fatty acid metabolism in chronic kidney disease.
Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides.
Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats.
Yang Q, Sun S, Liu W, Liu Q, Wang J
Biochemical and biophysical research communications 2020 May 7;525(3):639-645
Biochemical and biophysical research communications 2020 May 7;525(3):639-645
CPT1A plays a key role in the development and treatment of multiple sclerosis and experimental autoimmune encephalomyelitis.
Mørkholt AS, Trabjerg MS, Oklinski MKE, Bolther L, Kroese LJ, Pritchard CEJ, Huijbers IJ, Nieland JDV
Scientific reports 2019 Sep 16;9(1):13299
Scientific reports 2019 Sep 16;9(1):13299
Paracrine-endocrine FGF chimeras as potent therapeutics for metabolic diseases.
Zhao L, Niu J, Lin H, Zhao J, Liu Y, Song Z, Xiang C, Wang X, Yang Y, Li X, Mohammadi M, Huang Z
EBioMedicine 2019 Oct;48:462-477
EBioMedicine 2019 Oct;48:462-477
Troxerutin improves hepatic lipid homeostasis by restoring NAD(+)-depletion-mediated dysfunction of lipin 1 signaling in high-fat diet-treated mice.
Zhang ZF, Fan SH, Zheng YL, Lu J, Wu DM, Shan Q, Hu B
Biochemical pharmacology 2014 Sep 1;91(1):74-86
Biochemical pharmacology 2014 Sep 1;91(1):74-86
A regulatory role for microRNA 33* in controlling lipid metabolism gene expression.
Goedeke L, Vales-Lara FM, Fenstermaker M, Cirera-Salinas D, Chamorro-Jorganes A, Ramírez CM, Mattison JA, de Cabo R, Suárez Y, Fernández-Hernando C
Molecular and cellular biology 2013 Jun;33(11):2339-52
Molecular and cellular biology 2013 Jun;33(11):2339-52
Dysregulation of hepatic fatty acid metabolism in chronic kidney disease.
Jin K, Norris K, Vaziri ND
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2013 Feb;28(2):313-20
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2013 Feb;28(2):313-20
Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides.
Rayner KJ, Esau CC, Hussain FN, McDaniel AL, Marshall SM, van Gils JM, Ray TD, Sheedy FJ, Goedeke L, Liu X, Khatsenko OG, Kaimal V, Lees CJ, Fernandez-Hernando C, Fisher EA, Temel RE, Moore KJ
Nature 2011 Oct 19;478(7369):404-7
Nature 2011 Oct 19;478(7369):404-7
Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats.
Pocai A, Lam TK, Obici S, Gutierrez-Juarez R, Muse ED, Arduini A, Rossetti L
The Journal of clinical investigation 2006 Apr;116(4):1081-91
The Journal of clinical investigation 2006 Apr;116(4):1081-91
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CPT1A Antibody [NB100-53791] - (0.1ug/ml) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CPT1A Antibody [NB100-53791] - Staining of MCF7 cell lysate (35 ug protein in RIPA buffer). Antibody at 2 ug/mL. Detected by chemiluminescence.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CPT1A Antibody [NB100-53791] - (4 ug/ml) staining of paraffin embedded Human Kidney Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CPT1A Antibody [NB100-53791] - (4 ug/ml) staining of paraffin embedded Human Heart. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.