FNab06263

antibody from FineTest Biotech

Targeting: PDE9A

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

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Validation data

Product number: FNab06263 - Provider product page
Provider: FineTest Biotech
Product name: PDE9A antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP(PubMed:9624146, PubMed:18757755, PubMed:21483814). Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart(PubMed:25799991). Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein(Probable). In brain, involved in cognitive function, such as learning and long-term memory(By similarity).
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: phosphodiesterase 9A
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

PDE9A protein structure - FNab06263 shown in red.