305212

antibody from BioLegend

Targeting: CD80 B7-1, B7.1, CD28LG, CD28LG1

Western blot

Immunoprecipitation

Immunohistochemistry

Blocking/Neutralizing

Antibody data

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Validation data

Product number: 305212 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#305212, RRID:AB_314508
Product name: LEAF™ Purified anti-human CD80 [2D10]
Antibody type: Monoclonal
Antigen: CD80
Description: CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation.
Reactivity: Human, Simian
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Vial size: 500 µg
Concentration: 1 mg/ml
Storage: The antibody solution should be stored undiluted at 4°C. This LEAF™ solution contains no preservative; handle under aseptic conditions.

CD80 protein structure - 305212 shown in red.