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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [2]
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- Product number
- MAB0053 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB0053, RRID:AB_1018847
- Product name
- TBK1 monoclonal antibody, clone 108A429
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against synthetic peptide of TBK1.
- Antigen sequence
YYQFKKDKAERRLAYC- Isotype
- IgG
- Antibody clone number
- 108A429
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Glucocorticoids inhibit IRF3 phosphorylation in response to Toll-like receptor-3 and -4 by targeting TBK1 activation.
Regulation of IkappaB kinase epsilon expression by the androgen receptor and the nuclear factor-kappaB transcription factor in prostate cancer.
Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells.
IKK-i signals through IRF3 and NFkappaB to mediate the production of inflammatory cytokines.
Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells.
McCoy CE, Carpenter S, Pålsson-McDermott EM, Gearing LJ, O'Neill LA
The Journal of biological chemistry 2008 May 23;283(21):14277-85
The Journal of biological chemistry 2008 May 23;283(21):14277-85
Regulation of IkappaB kinase epsilon expression by the androgen receptor and the nuclear factor-kappaB transcription factor in prostate cancer.
Péant B, Diallo JS, Lessard L, Delvoye N, Le Page C, Saad F, Mes-Masson AM
Molecular cancer research : MCR 2007 Jan;5(1):87-94
Molecular cancer research : MCR 2007 Jan;5(1):87-94
Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells.
Aksoy E, Albarani V, Nguyen M, Laes JF, Ruelle JL, De Wit D, Willems F, Goldman M, Goriely S
Blood 2007 Apr 1;109(7):2887-93
Blood 2007 Apr 1;109(7):2887-93
IKK-i signals through IRF3 and NFkappaB to mediate the production of inflammatory cytokines.
Sankar S, Chan H, Romanow WJ, Li J, Bates RJ
Cellular signalling 2006 Jul;18(7):982-93
Cellular signalling 2006 Jul;18(7):982-93
Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells.
Osterlund P, Veckman V, Sirén J, Klucher KM, Hiscott J, Matikainen S, Julkunen I
Journal of virology 2005 Aug;79(15):9608-17
Journal of virology 2005 Aug;79(15):9608-17
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of TBK1. Using TBK1 monoclonal antibody, clone 108A429 (Cat # MAB0053) 2 ug/mL dilution against 10 ug/lane of lysate from 293 cells transfected with human TBK1 cDNA.
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of TBK1 in (A) human Daudi cell lysate and (B) mouse RAW cell lysate using TBK1 monoclonal antibody, clone 108A429 (Cat # MAB0053) at 2 ug/mL .
