BS7284

antibody from Bioworld Technology, Inc
Targeting: NR1I2 BXR, ONR1, PAR2, PXR, SXR
Provider product page for BS7284
Western blot
Immunohistochemistry

Antibody data

Product number
BS7284 - Provider product page
Provider
Bioworld Technology, Inc
Product name
NR1I2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human NR1I2.
Description
This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
NR1I2 protein structure - BS7284 shown in red.