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LearnH00055832-M01
antibody from Novus Biologicals
Targeting: CAND1
DKFZp434M1414, KIAA0829, TIP120, TIP120A
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- ELISA [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- H00055832-M01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00055832-M01, RRID:AB_2259471
- Product name
- Mouse Monoclonal TIP120A Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. CAND1 - cullin-associated and neddylation-dissociated 1
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Targeting CAND1 promotes caspase-8/RIP1-dependent apoptosis in liver cancer cells.
Distinct outcomes of CRL-Nedd8 pathway inhibition reveal cancer cell plasticity.
CAND1 promotes PLK4-mediated centriole overduplication and is frequently disrupted in prostate cancer.
CAND1 promotes PLK4-mediated centriole overduplication and is frequently disrupted in prostate cancer.
COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding.
Che Z, Liu F, Zhang W, McGrath M, Hou D, Chen P, Song C, Yang D
American journal of translational research 2018;10(5):1357-1372
American journal of translational research 2018;10(5):1357-1372
Distinct outcomes of CRL-Nedd8 pathway inhibition reveal cancer cell plasticity.
Rulina AV, Mittler F, Obeid P, Gerbaud S, Guyon L, Sulpice E, Kermarrec F, Assard N, Dolega ME, Gidrol X, Balakirev MY
Cell death & disease 2016 Dec 1;7(12):e2505
Cell death & disease 2016 Dec 1;7(12):e2505
CAND1 promotes PLK4-mediated centriole overduplication and is frequently disrupted in prostate cancer.
Korzeniewski N, Hohenfellner M, Duensing S
Neoplasia (New York, N.Y.) 2012 Sep;14(9):799-806
Neoplasia (New York, N.Y.) 2012 Sep;14(9):799-806
CAND1 promotes PLK4-mediated centriole overduplication and is frequently disrupted in prostate cancer.
Korzeniewski N, Hohenfellner M, Duensing S
Neoplasia (New York, N.Y.) 2012 Sep;14(9):799-806
Neoplasia (New York, N.Y.) 2012 Sep;14(9):799-806
COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding.
Mao X, Gluck N, Chen B, Starokadomskyy P, Li H, Maine GN, Burstein E
The Journal of biological chemistry 2011 Sep 16;286(37):32355-65
The Journal of biological chemistry 2011 Sep 16;286(37):32355-65
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TIP120A Antibody (5D7) [H00055832-M01] - CAND1 monoclonal antibody (M01), clone 5D7 Analysis of CAND1 expression in Hela S3 NE.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Sandwich ELISA: TIP120A Antibody (5D7) [H00055832-M01] - Detection limit for recombinant GST tagged CAND1 is approximately 0.03ng/ml as a capture antibody.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunocytochemistry/Immunofluorescence: TIP120A Antibody (5D7) [H00055832-M01] - Analysis of monoclonal antibody to CAND1 on HeLa cell. Antibody concentration 10 ug/ml.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TIP120A Antibody (5D7) [H00055832-M01] - Analysis of monoclonal antibody to CAND1 on formalin-fixed paraffin-embedded human placenta. Antibody concentration 3 ug/ml.
