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LearnNB100-56722
antibody from Novus Biologicals
Targeting: TLR2
CD282, TIL4
Western blot
ELISA Immunocytochemistry Immunoprecipitation Flow cytometry Blocking/Neutralizing Functional assayAntibody data
- Antibody Data
- Antigen structure
- References [65]
- Comments [0]
- Validations
- Western blot [2]
- Flow cytometry [7]
- Blocking/Neutralizing [1]
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- Product number
- NB100-56722 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-56722, RRID:AB_2204727
- Product name
- Mouse Monoclonal TLR2 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified.
- Reactivity
- Human, Mouse, Rat, Canine, Rabbit
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Nfa34810 Facilitates Nocardia farcinica Invasion of Host Cells and Stimulates Tumor Necrosis Factor Alpha Secretion through Activation of the NF-κB and Mitogen-Activated Protein Kinase Pathways via Toll-Like Receptor 4.
Mechanistic Roles of Matrilin-2 and Klotho in Modulating the Inflammatory Activity of Human Aortic Valve Cells.
Oxidative Stress Induces Expression of the Toll-Like Receptors (TLRs) 2 and 4 in the Human Peripheral Blood Mononuclear Cells: Implications for Metabolic Inflammation.
Role of whole saliva in the efficacy of sublingual immunotherapy in seasonal allergic rhinitis.
Toll-like receptors blocking restores in vitro microbicidal activity in latent tuberculosis-infected subjects.
CD89 Is a Potent Innate Receptor for Bacteria and Mediates Host Protection from Sepsis.
Substance P represents a novel first-line defense mechanism in the nose.
Toll-like receptor expression and apoptosis morphological patterns in female rat hearts with takotsubo syndrome induced by isoprenaline.
Vitamin D Promotes Pneumococcal Killing and Modulates Inflammatory Responses in Primary Human Neutrophils.
NF-κB Links TLR2 and PAR1 to Soluble Immunomodulator Factor Secretion in Human Platelets.
ADAMTS5 Deficiency in Calcified Aortic Valves Is Associated With Elevated Pro-Osteogenic Activity in Valvular Interstitial Cells.
Invasive Streptococcus mutans induces inflammatory cytokine production in human aortic endothelial cells via regulation of intracellular toll-like receptor 2 and nucleotide-binding oligomerization domain 2.
Toll-Like Receptor 1/2 and 5 Ligands Enhance the Expression of Cyclin D1 and D3 and Induce Proliferation in Mantle Cell Lymphoma.
Azithromycin modulates immune response of human monocyte-derived dendritic cells and CD4+ T cells.
Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination.
Vaccination against canine leishmaniosis increases the phagocytic activity, nitric oxide production and expression of cell activation/migration molecules in neutrophils and monocytes.
Aberrant Expression of Bacterial Pattern Recognition Receptor NOD2 of Basophils and Microbicidal Peptides in Atopic Dermatitis.
The immunologically active oligosaccharides isolated from wheatgrass modulate monocytes via Toll-like receptor-2 signaling.
Porphyromonas gingivalis lipopolysaccharide inhibits trophoblast invasion in the presence of nicotine.
Toll-like receptor 3 expression and function in childhood idiopathic nephrotic syndrome.
BMP-2 and TGF-β1 mediate biglycan-induced pro-osteogenic reprogramming in aortic valve interstitial cells.
Involvement of Toll-like receptors on Helicobacter pylori-induced immunity.
Leishmania mexicana lipophosphoglycan activates ERK and p38 MAP kinase and induces production of proinflammatory cytokines in human macrophages through TLR2 and TLR4.
1,25-Dihydroxyvitamin D3 up-regulates TLR10 while down-regulating TLR2, 4, and 5 in human monocyte THP-1.
Toll-like receptor (TLR) expression of immune system cells from metastatic breast cancer patients with circulating tumor cells.
Cholesterol oxidase is indispensable in the pathogenesis of Mycobacterium tuberculosis.
Characterization of the Toll-like receptor expression profile in human multiple myeloma cells.
The immunologically active oligosaccharides isolated from wheatgrass modulate monocytes via Toll-like receptor-2 signaling.
Identification of lineage relationships and novel markers of blood and skin human dendritic cells.
The role of 3-ketosteroid 1(2)-dehydrogenase in the pathogenicity of Mycobacterium tuberculosis.
Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21.
Cytoadherence-dependent induction of inflammatory responses by Mycoplasma pneumoniae.
Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses.
Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVS-dependent and MDA5/MAVS/RNA polymerase III-independent pathways.
Differential but direct abolishment of human regulatory T cell suppressive capacity by various TLR2 ligands.
Neisseria gonorrhoeae enhances HIV-1 infection of primary resting CD4+ T cells through TLR2 activation.
The Escherichia coli mqsR and ygiT genes encode a new toxin-antitoxin pair.
Toll-like receptor agonists induce inflammation and cell death in a model of head and neck squamous cell carcinomas.
Toll-like receptor 2 and NALP2 mediate induction of human beta-defensins by fusobacterium nucleatum in gingival epithelial cells.
Pro-osteogenic phenotype of human aortic valve interstitial cells is associated with higher levels of Toll-like receptors 2 and 4 and enhanced expression of bone morphogenetic protein 2.
Human lymphatic endothelial cells express multiple functional TLRs.
Human lymphatic endothelial cells express multiple functional TLRs.
The probiotic Escherichia coli strain Nissle 1917 induces gammadelta T cell apoptosis via caspase- and FasL-dependent pathways.
Antibodies specific for human or murine Toll-like receptors detect canine leukocytes by flow cytometry.
TLR2 and TLR4 expression on the immune cells of tuberculous pleural fluid.
Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils.
Signal transduction and nuclear responses in Staphylococcus aureus-induced expression of human beta-defensin 3 in skin keratinocytes.
High-avidity antitumor T-cell generation by toll receptor 8-primed, myeloid- derived dendritic cells is mediated by IL-12 production.
A dipalmitoylated lipoprotein from Mycoplasma pneumoniae activates NF-kappa B through TLR1, TLR2, and TLR6.
A dipalmitoylated lipoprotein from Mycoplasma pneumoniae activates NF-kappa B through TLR1, TLR2, and TLR6.
Expression and function of Toll-like receptor 2 in canine blood phagocytes.
Expression of mRNA and proteins for toll-like receptors, associated molecules, defensins and LL-37 by SRIK-NKL, a CD8+ NK/T cell line.
Deviation from major codons in the Toll-like receptor genes is associated with low Toll-like receptor expression.
Evidence of Toll-like receptor molecules on human platelets.
Lipid-associated membrane proteins of Mycoplasma fermentans and M. penetrans activate human immunodeficiency virus long-terminal repeats through Toll-like receptors.
Highly purified lipoteichoic acid activates neutrophil granulocytes and delays their spontaneous apoptosis via CD14 and TLR2.
Innate immune recognition of invasive bacteria accelerates atherosclerosis in apolipoprotein E-deficient mice.
Toll-like receptor expression in human keratinocytes: nuclear factor kappaB controlled gene activation by Staphylococcus aureus is toll-like receptor 2 but not toll-like receptor 4 or platelet activating factor receptor dependent.
Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells.
Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells.
Differential expression of Toll-like receptor 2 in human cells.
Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kappa B activation.
Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kappa B activation.
Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.
Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.
Ji X, Zhang X, Li H, Sun L, Hou X, Song H, Han L, Xu S, Qiu X, Wang X, Zheng N, Li Z
Infection and immunity 2020 Mar 23;88(4)
Infection and immunity 2020 Mar 23;88(4)
Mechanistic Roles of Matrilin-2 and Klotho in Modulating the Inflammatory Activity of Human Aortic Valve Cells.
The E, Yao Q, Zhang P, Zhai Y, Ao L, Fullerton DA, Meng X
Cells 2020 Feb 7;9(2)
Cells 2020 Feb 7;9(2)
Oxidative Stress Induces Expression of the Toll-Like Receptors (TLRs) 2 and 4 in the Human Peripheral Blood Mononuclear Cells: Implications for Metabolic Inflammation.
Akhter N, Madhoun A, Arefanian H, Wilson A, Kochumon S, Thomas R, Shenouda S, Al-Mulla F, Ahmad R, Sindhu S
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2019;53(1):1-18
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2019;53(1):1-18
Role of whole saliva in the efficacy of sublingual immunotherapy in seasonal allergic rhinitis.
Haruna T, Kariya S, Fujiwara T, Yuta A, Higaki T, Zhao P, Ogawa Y, Kanai K, Hirata Y, Oka A, Nishizaki K, Okano M
Allergology international : official journal of the Japanese Society of Allergology 2019 Jan;68(1):82-89
Allergology international : official journal of the Japanese Society of Allergology 2019 Jan;68(1):82-89
Toll-like receptors blocking restores in vitro microbicidal activity in latent tuberculosis-infected subjects.
Coelho da Silva FD, Covre LP, Stringari LL, Palaci M, Dietze R, Gomes DCO, Ribeiro-Rodrigues R
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2019 Feb 1;23(2):212-218
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2019 Feb 1;23(2):212-218
CD89 Is a Potent Innate Receptor for Bacteria and Mediates Host Protection from Sepsis.
de Tymowski C, Heming N, Correia MDT, Abbad L, Chavarot N, Le Stang MB, Flament H, Bex J, Boedec E, Bounaix C, Soler-Torronteras R, Denamur E, Galicier L, Oksenhendler E, Fehling HJ, Pinheiro da Silva F, Benhamou M, Monteiro RC, Ben Mkaddem S
Cell reports 2019 Apr 16;27(3):762-775.e5
Cell reports 2019 Apr 16;27(3):762-775.e5
Substance P represents a novel first-line defense mechanism in the nose.
Larsson O, Tengroth L, Xu Y, Uddman R, Kumlien Georén S, Cardell LO
The Journal of allergy and clinical immunology 2018 Jan;141(1):128-136.e3
The Journal of allergy and clinical immunology 2018 Jan;141(1):128-136.e3
Toll-like receptor expression and apoptosis morphological patterns in female rat hearts with takotsubo syndrome induced by isoprenaline.
Kołodzińska A, Czarzasta K, Szczepankiewicz B, Główczyńska R, Fojt A, Ilczuk T, Budnik M, Krasuski K, Folta M, Cudnoch-Jędrzejewska A, Górnicka B, Opolski G
Life sciences 2018 Apr 15;199:112-121
Life sciences 2018 Apr 15;199:112-121
Vitamin D Promotes Pneumococcal Killing and Modulates Inflammatory Responses in Primary Human Neutrophils.
Subramanian K, Bergman P, Henriques-Normark B
Journal of innate immunity 2017;9(4):375-386
Journal of innate immunity 2017;9(4):375-386
NF-κB Links TLR2 and PAR1 to Soluble Immunomodulator Factor Secretion in Human Platelets.
Damien P, Cognasse F, Payrastre B, Spinelli SL, Blumberg N, Arthaud CA, Eyraud MA, Phipps RP, McNicol A, Pozzetto B, Garraud O, Hamzeh-Cognasse H
Frontiers in immunology 2017;8:85
Frontiers in immunology 2017;8:85
ADAMTS5 Deficiency in Calcified Aortic Valves Is Associated With Elevated Pro-Osteogenic Activity in Valvular Interstitial Cells.
Li F, Song R, Ao L, Reece TB, Cleveland JC Jr, Dong N, Fullerton DA, Meng X
Arteriosclerosis, thrombosis, and vascular biology 2017 Jul;37(7):1339-1351
Arteriosclerosis, thrombosis, and vascular biology 2017 Jul;37(7):1339-1351
Invasive Streptococcus mutans induces inflammatory cytokine production in human aortic endothelial cells via regulation of intracellular toll-like receptor 2 and nucleotide-binding oligomerization domain 2.
Nagata E, Oho T
Molecular oral microbiology 2017 Apr;32(2):131-141
Molecular oral microbiology 2017 Apr;32(2):131-141
Toll-Like Receptor 1/2 and 5 Ligands Enhance the Expression of Cyclin D1 and D3 and Induce Proliferation in Mantle Cell Lymphoma.
Mastorci K, Muraro E, Pasini E, Furlan C, Sigalotti L, Cinco M, Dolcetti R, Fratta E
PloS one 2016;11(4):e0153823
PloS one 2016;11(4):e0153823
Azithromycin modulates immune response of human monocyte-derived dendritic cells and CD4+ T cells.
Lin SJ, Kuo ML, Hsiao HS, Lee PT
International immunopharmacology 2016 Nov;40:318-326
International immunopharmacology 2016 Nov;40:318-326
Pellino-1 confers chemoresistance in lung cancer cells by upregulating cIAP2 through Lys63-mediated polyubiquitination.
Jeon YK, Kim CK, Koh J, Chung DH, Ha GH
Oncotarget 2016 Jul 5;7(27):41811-41824
Oncotarget 2016 Jul 5;7(27):41811-41824
Vaccination against canine leishmaniosis increases the phagocytic activity, nitric oxide production and expression of cell activation/migration molecules in neutrophils and monocytes.
Moreira ML, Costa-Pereira C, Alves ML, Marteleto BH, Ribeiro VM, Peruhype-Magalhães V, Giunchetti RC, Martins-Filho OA, Araújo MS
Veterinary parasitology 2016 Apr 15;220:33-45
Veterinary parasitology 2016 Apr 15;220:33-45
Aberrant Expression of Bacterial Pattern Recognition Receptor NOD2 of Basophils and Microbicidal Peptides in Atopic Dermatitis.
Wong CK, Chu IM, Hon KL, Tsang MS, Lam CW
Molecules (Basel, Switzerland) 2016 Apr 11;21(4):471
Molecules (Basel, Switzerland) 2016 Apr 11;21(4):471
The immunologically active oligosaccharides isolated from wheatgrass modulate monocytes via Toll-like receptor-2 signaling.
Tsai CC, Lin CR, Tsai HY, Chen CJ, Li WT, Yu HM, Ke YY, Hsieh WY, Chang CY, Wu YT, Chen ST, Wong CH
The Journal of biological chemistry 2015 May 8;290(19):11935
The Journal of biological chemistry 2015 May 8;290(19):11935
Porphyromonas gingivalis lipopolysaccharide inhibits trophoblast invasion in the presence of nicotine.
Komine-Aizawa S, Hirohata N, Aizawa S, Abiko Y, Hayakawa S
Placenta 2015 Jan;36(1):27-33
Placenta 2015 Jan;36(1):27-33
Toll-like receptor 3 expression and function in childhood idiopathic nephrotic syndrome.
Jamin A, Dehoux L, Dossier C, Fila M, Heming N, Monteiro RC, Deschênes G
Clinical and experimental immunology 2015 Dec;182(3):332-45
Clinical and experimental immunology 2015 Dec;182(3):332-45
BMP-2 and TGF-β1 mediate biglycan-induced pro-osteogenic reprogramming in aortic valve interstitial cells.
Song R, Fullerton DA, Ao L, Zheng D, Zhao KS, Meng X
Journal of molecular medicine (Berlin, Germany) 2015 Apr;93(4):403-12
Journal of molecular medicine (Berlin, Germany) 2015 Apr;93(4):403-12
Involvement of Toll-like receptors on Helicobacter pylori-induced immunity.
Käbisch R, Mejías-Luque R, Gerhard M, Prinz C
PloS one 2014;9(8):e104804
PloS one 2014;9(8):e104804
Leishmania mexicana lipophosphoglycan activates ERK and p38 MAP kinase and induces production of proinflammatory cytokines in human macrophages through TLR2 and TLR4.
Rojas-Bernabé A, Garcia-Hernández O, Maldonado-Bernal C, Delegado-Dominguez J, Ortega E, Gutiérrez-Kobeh L, Becker I, Aguirre-Garcia M
Parasitology 2014 May;141(6):788-800
Parasitology 2014 May;141(6):788-800
1,25-Dihydroxyvitamin D3 up-regulates TLR10 while down-regulating TLR2, 4, and 5 in human monocyte THP-1.
Verma R, Jung JH, Kim JY
The Journal of steroid biochemistry and molecular biology 2014 May;141:1-6
The Journal of steroid biochemistry and molecular biology 2014 May;141:1-6
Toll-like receptor (TLR) expression of immune system cells from metastatic breast cancer patients with circulating tumor cells.
Green TL, Santos MF, Ejaeidi AA, Craft BS, Lewis RE, Cruse JM
Experimental and molecular pathology 2014 Aug;97(1):44-8
Experimental and molecular pathology 2014 Aug;97(1):44-8
Cholesterol oxidase is indispensable in the pathogenesis of Mycobacterium tuberculosis.
Klink M, Brzezinska M, Szulc I, Brzostek A, Kielbik M, Sulowska Z, Dziadek J
PloS one 2013;8(9):e73333
PloS one 2013;8(9):e73333
Characterization of the Toll-like receptor expression profile in human multiple myeloma cells.
Abdi J, Mutis T, Garssen J, Redegeld F
PloS one 2013;8(4):e60671
PloS one 2013;8(4):e60671
The immunologically active oligosaccharides isolated from wheatgrass modulate monocytes via Toll-like receptor-2 signaling.
Tsai CC, Lin CR, Tsai HY, Chen CJ, Li WT, Yu HM, Ke YY, Hsieh WY, Chang CY, Wu YT, Chen ST, Wong CH
The Journal of biological chemistry 2013 Jun 14;288(24):17689-97
The Journal of biological chemistry 2013 Jun 14;288(24):17689-97
Identification of lineage relationships and novel markers of blood and skin human dendritic cells.
Harman AN, Bye CR, Nasr N, Sandgren KJ, Kim M, Mercier SK, Botting RA, Lewin SR, Cunningham AL, Cameron PU
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):66-79
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):66-79
The role of 3-ketosteroid 1(2)-dehydrogenase in the pathogenicity of Mycobacterium tuberculosis.
Brzezinska M, Szulc I, Brzostek A, Klink M, Kielbik M, Sulowska Z, Pawelczyk J, Dziadek J
BMC microbiology 2013 Feb 20;13:43
BMC microbiology 2013 Feb 20;13:43
Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21.
Merline R, Moreth K, Beckmann J, Nastase MV, Zeng-Brouwers J, Tralhão JG, Lemarchand P, Pfeilschifter J, Schaefer RM, Iozzo RV, Schaefer L
Science signaling 2011 Nov 15;4(199):ra75
Science signaling 2011 Nov 15;4(199):ra75
Cytoadherence-dependent induction of inflammatory responses by Mycoplasma pneumoniae.
Shimizu T, Kida Y, Kuwano K
Immunology 2011 May;133(1):51-61
Immunology 2011 May;133(1):51-61
Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses.
Dasgupta G, Chentoufi AA, You S, Falatoonzadeh P, Urbano LA, Akhtarmalik A, Nguyen K, Ablabutyan L, Nesburn AB, BenMohamed L
Investigative ophthalmology & visual science 2011 May 17;52(6):3321-33
Investigative ophthalmology & visual science 2011 May 17;52(6):3321-33
Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVS-dependent and MDA5/MAVS/RNA polymerase III-independent pathways.
Melchjorsen J, Rintahaka J, Søby S, Horan KA, Poltajainen A, Østergaard L, Paludan SR, Matikainen S
Journal of virology 2010 Nov;84(21):11350-8
Journal of virology 2010 Nov;84(21):11350-8
Differential but direct abolishment of human regulatory T cell suppressive capacity by various TLR2 ligands.
Oberg HH, Ly TT, Ussat S, Meyer T, Kabelitz D, Wesch D
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):4733-40
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):4733-40
Neisseria gonorrhoeae enhances HIV-1 infection of primary resting CD4+ T cells through TLR2 activation.
Ding J, Rapista A, Teleshova N, Mosoyan G, Jarvis GA, Klotman ME, Chang TL
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):2814-24
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):2814-24
The Escherichia coli mqsR and ygiT genes encode a new toxin-antitoxin pair.
Kasari V, Kurg K, Margus T, Tenson T, Kaldalu N
Journal of bacteriology 2010 Jun;192(11):2908-19
Journal of bacteriology 2010 Jun;192(11):2908-19
Toll-like receptor agonists induce inflammation and cell death in a model of head and neck squamous cell carcinomas.
Rydberg C, Månsson A, Uddman R, Riesbeck K, Cardell LO
Immunology 2009 Sep;128(1 Suppl):e600-11
Immunology 2009 Sep;128(1 Suppl):e600-11
Toll-like receptor 2 and NALP2 mediate induction of human beta-defensins by fusobacterium nucleatum in gingival epithelial cells.
Ji S, Shin JE, Kim YS, Oh JE, Min BM, Choi Y
Infection and immunity 2009 Mar;77(3):1044-52
Infection and immunity 2009 Mar;77(3):1044-52
Pro-osteogenic phenotype of human aortic valve interstitial cells is associated with higher levels of Toll-like receptors 2 and 4 and enhanced expression of bone morphogenetic protein 2.
Yang X, Fullerton DA, Su X, Ao L, Cleveland JC Jr, Meng X
Journal of the American College of Cardiology 2009 Feb 10;53(6):491-500
Journal of the American College of Cardiology 2009 Feb 10;53(6):491-500
Human lymphatic endothelial cells express multiple functional TLRs.
Pegu A, Qin S, Fallert Junecko BA, Nisato RE, Pepper MS, Reinhart TA
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 1;180(5):3399-405
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 1;180(5):3399-405
Human lymphatic endothelial cells express multiple functional TLRs.
Pegu A, Qin S, Fallert Junecko BA, Nisato RE, Pepper MS, Reinhart TA
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 1;180(5):3399-405
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 1;180(5):3399-405
The probiotic Escherichia coli strain Nissle 1917 induces gammadelta T cell apoptosis via caspase- and FasL-dependent pathways.
Guzy C, Paclik D, Schirbel A, Sonnenborn U, Wiedenmann B, Sturm A
International immunology 2008 Jul;20(7):829-40
International immunology 2008 Jul;20(7):829-40
Antibodies specific for human or murine Toll-like receptors detect canine leukocytes by flow cytometry.
Burgener IA, Jungi TW
Veterinary immunology and immunopathology 2008 Jul 15;124(1-2):184-91
Veterinary immunology and immunopathology 2008 Jul 15;124(1-2):184-91
TLR2 and TLR4 expression on the immune cells of tuberculous pleural fluid.
Prabha C, Rajashree P, Sulochana DD
Immunology letters 2008 Apr 15;117(1):26-34
Immunology letters 2008 Apr 15;117(1):26-34
Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils.
Wong CK, Cheung PF, Ip WK, Lam CW
American journal of respiratory cell and molecular biology 2007 Jul;37(1):85-96
American journal of respiratory cell and molecular biology 2007 Jul;37(1):85-96
Signal transduction and nuclear responses in Staphylococcus aureus-induced expression of human beta-defensin 3 in skin keratinocytes.
Menzies BE, Kenoyer A
Infection and immunity 2006 Dec;74(12):6847-54
Infection and immunity 2006 Dec;74(12):6847-54
High-avidity antitumor T-cell generation by toll receptor 8-primed, myeloid- derived dendritic cells is mediated by IL-12 production.
Xu S, Koldovsky U, Xu M, Wang D, Fitzpatrick E, Son G, Koski G, Czerniecki BJ
Surgery 2006 Aug;140(2):170-8
Surgery 2006 Aug;140(2):170-8
A dipalmitoylated lipoprotein from Mycoplasma pneumoniae activates NF-kappa B through TLR1, TLR2, and TLR6.
Shimizu T, Kida Y, Kuwano K
Journal of immunology (Baltimore, Md. : 1950) 2005 Oct 1;175(7):4641-6
Journal of immunology (Baltimore, Md. : 1950) 2005 Oct 1;175(7):4641-6
A dipalmitoylated lipoprotein from Mycoplasma pneumoniae activates NF-kappa B through TLR1, TLR2, and TLR6.
Shimizu T, Kida Y, Kuwano K
Journal of immunology (Baltimore, Md. : 1950) 2005 Oct 1;175(7):4641-6
Journal of immunology (Baltimore, Md. : 1950) 2005 Oct 1;175(7):4641-6
Expression and function of Toll-like receptor 2 in canine blood phagocytes.
Bazzocchi C, Mortarino M, Comazzi S, Bandi C, Franceschi A, Genchi C
Veterinary immunology and immunopathology 2005 Mar 10;104(1-2):15-9
Veterinary immunology and immunopathology 2005 Mar 10;104(1-2):15-9
Expression of mRNA and proteins for toll-like receptors, associated molecules, defensins and LL-37 by SRIK-NKL, a CD8+ NK/T cell line.
Srivastava MD, Srivastava BI
Leukemia research 2005 Jul;29(7):813-20
Leukemia research 2005 Jul;29(7):813-20
Deviation from major codons in the Toll-like receptor genes is associated with low Toll-like receptor expression.
Zhong F, Cao W, Chan E, Tay PN, Cahya FF, Zhang H, Lu J
Immunology 2005 Jan;114(1):83-93
Immunology 2005 Jan;114(1):83-93
Evidence of Toll-like receptor molecules on human platelets.
Cognasse F, Hamzeh H, Chavarin P, Acquart S, Genin C, Garraud O
Immunology and cell biology 2005 Apr;83(2):196-8
Immunology and cell biology 2005 Apr;83(2):196-8
Lipid-associated membrane proteins of Mycoplasma fermentans and M. penetrans activate human immunodeficiency virus long-terminal repeats through Toll-like receptors.
Shimizu T, Kida Y, Kuwano K
Immunology 2004 Sep;113(1):121-9
Immunology 2004 Sep;113(1):121-9
Highly purified lipoteichoic acid activates neutrophil granulocytes and delays their spontaneous apoptosis via CD14 and TLR2.
Lotz S, Aga E, Wilde I, van Zandbergen G, Hartung T, Solbach W, Laskay T
Journal of leukocyte biology 2004 Mar;75(3):467-77
Journal of leukocyte biology 2004 Mar;75(3):467-77
Innate immune recognition of invasive bacteria accelerates atherosclerosis in apolipoprotein E-deficient mice.
Gibson FC 3rd, Hong C, Chou HH, Yumoto H, Chen J, Lien E, Wong J, Genco CA
Circulation 2004 Jun 8;109(22):2801-6
Circulation 2004 Jun 8;109(22):2801-6
Toll-like receptor expression in human keratinocytes: nuclear factor kappaB controlled gene activation by Staphylococcus aureus is toll-like receptor 2 but not toll-like receptor 4 or platelet activating factor receptor dependent.
Mempel M, Voelcker V, Köllisch G, Plank C, Rad R, Gerhard M, Schnopp C, Fraunberger P, Walli AK, Ring J, Abeck D, Ollert M
The Journal of investigative dermatology 2003 Dec;121(6):1389-96
The Journal of investigative dermatology 2003 Dec;121(6):1389-96
Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells.
Medvedev AE, Lentschat A, Wahl LM, Golenbock DT, Vogel SN
Journal of immunology (Baltimore, Md. : 1950) 2002 Nov 1;169(9):5209-16
Journal of immunology (Baltimore, Md. : 1950) 2002 Nov 1;169(9):5209-16
Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor-associated kinase 1 activation in endotoxin-tolerant cells.
Medvedev AE, Lentschat A, Wahl LM, Golenbock DT, Vogel SN
Journal of immunology (Baltimore, Md. : 1950) 2002 Nov 1;169(9):5209-16
Journal of immunology (Baltimore, Md. : 1950) 2002 Nov 1;169(9):5209-16
Differential expression of Toll-like receptor 2 in human cells.
Flo TH, Halaas O, Torp S, Ryan L, Lien E, Dybdahl B, Sundan A, Espevik T
Journal of leukocyte biology 2001 Mar;69(3):474-81
Journal of leukocyte biology 2001 Mar;69(3):474-81
Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kappa B activation.
Faure E, Thomas L, Xu H, Medvedev A, Equils O, Arditi M
Journal of immunology (Baltimore, Md. : 1950) 2001 Feb 1;166(3):2018-24
Journal of immunology (Baltimore, Md. : 1950) 2001 Feb 1;166(3):2018-24
Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kappa B activation.
Faure E, Thomas L, Xu H, Medvedev A, Equils O, Arditi M
Journal of immunology (Baltimore, Md. : 1950) 2001 Feb 1;166(3):2018-24
Journal of immunology (Baltimore, Md. : 1950) 2001 Feb 1;166(3):2018-24
Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.
Flo TH, Halaas O, Lien E, Ryan L, Teti G, Golenbock DT, Sundan A, Espevik T
Journal of immunology (Baltimore, Md. : 1950) 2000 Feb 15;164(4):2064-9
Journal of immunology (Baltimore, Md. : 1950) 2000 Feb 15;164(4):2064-9
Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide.
Flo TH, Halaas O, Lien E, Ryan L, Teti G, Golenbock DT, Sundan A, Espevik T
Journal of immunology (Baltimore, Md. : 1950) 2000 Feb 15;164(4):2064-9
Journal of immunology (Baltimore, Md. : 1950) 2000 Feb 15;164(4):2064-9
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Supportive validation
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- Western Blot: TLR2 Antibody (TL2.1) [NB100-56722] - Using the Biotin direct conjugate. Detection of TLR2 mRNA in multiple cell lines. No detection was observed in L363 or Fravel cell lines. [PMID: 23593278]
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- Western Blot: TLR2 Antibody (TL2.1) [NB100-56722] - Expression of TLR2 was determined by western blotting. The immunoreactivity of the anti-TLR2 was confirmed with human intestinal lysate. Data are representative for analysis of >=2 independent experiments. Image collected and cropped by CiteAb from the following publication (//doi.org/10.1371/journal.pone.0060671) licensed under a CC-BY licence.
Supportive validation
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- Flow Cytometry: TLR2 Antibody (TL2.1) [NB100-56722] - Analysis using Azide Free version of NB100-56722. Intracellular TLR2 in 10^6 PBMs using 2 ug of TLR2 antibody. Shaded histogram: cells without antibody. Green: isotype control. Red: TLR2 antibody. Goat anti-mouse IgG FITC secondary antibody.
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- Flow Cytometry: TLR2 Antibody (TL2.1) [NB100-56722] - Analysis using Azide/BSA FREE version of NB100-56726. Cell surface flow analysis of TLR2 in 10^6 PBMCs using 1 ug of this antibody. Shaded histogram: cells without antibody. Green: isotype control. Red: anti-TLR2 antibody.
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- Flow Cytometry: TLR2 Antibody (TL2.1) [NB100-56722] - Analysis using the FITC conjugate of NB100-56726. Staining of TLR2 in 10^6 ThP1 cells using 2 ug of this antibody. The closed histogram represents cells alone, green represents isotype control, red represents anti-TLR2 antibody.
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- Flow Cytometry: TLR2 Antibody (TL2.1) [NB100-56722] - Analysis using the PE conjugate of NB100-56726. Staining of TLR2 on PBMC using this antibody at 1 ug/10^6 cells. Green represents isotype control this antibody; red represents anti-TLR2 antibody.
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- Flow Cytometry: TLR2 Antibody (TL2.1) [NB100-56722] - Analysis using the FITC conjugate of NB100-56726. Staining of TLR2 in 10^6 PBMCs (lymphocyte-gated) using 2 ugs ofMouse IgG2a Kappa, and red represents TLR2 antibody.
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- Flow (Cell Surface): TLR2 Antibody (TL2.1) [NB100-56722] - Flow (Cell Surface): - Azide Free [NB100-56726] - Analysis using the PE conjugate of NB100-56726. Staining of TLR2 on stable transfected cell line using this antibody at 1 ug/10^6 cells. Green: isotype control. Red: anti-TLR2 antibody. Image using the Azide Free form of this antibody.
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- Flow Cytometry: TLR2 Antibody (TL2.1) [NB100-56722] - Monitoring of TLR2 expression in normal B cells and primary MCL cells cultured for 24h in the absence/presence of CD40L, IL-4, and TLR ligands. Filled curves refer to isotypic control, empty curves to the TLR2 antibody (NB100-56722) of untreated samples. Dotted histograms represent CD40L+IL4 activated cells, dashed curves indicate CD40L+IL4 activated cells further treated with TLR ligands. Image collected and cropped by CiteAb from the following publication (//doi.org/10.1371/journal.pone.0153823) licensed under a CC-BY licence.
Supportive validation
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- Block/Neutralize: TLR2 Antibody (TL2.1) [NB100-56722] - Human monocyte-derived DCs were pre-incubated wit TLR-neutralizing antibodies including TLR2 antibody (NB100-56722) for 1 h. Afterwards, DCs were infected with H. pylori G27 (MOI 5) and the levels of the costimulatory molecule CD86 and the maturation marker CD83 were analyzed by FACS on CD11c+ cells 24 h post-infection. Data are presented as mean +/- SD of five independent experiments. *p
