Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS1318 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS1318, RRID:AB_1664033
- Product name
- S100 Ï« (A18) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to the N-terminal of Human S100 Ï«.
- Description
- The family of EF-hand type Ca2+-binding proteins includes calbindin (previously designated vitamin D-dependent Ca 2+-binding protein), S-100 Ï« and ÉÇ, calgranulins A (also designated MRP8), B (also designated MRP14) and C (S-100 like proteins), and the parvalbumin family members, including parvalbumin Ï« and parvalbumin ÉÇ (also designated oncomodulin). The S-100 protein is involved in the regulation of cellular processes such as cell cycle progression and differentiation. Research also indicates that the S-100 protein may function in the activation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly and inhibition of protein kinase C mediated phosphorylation. Two S-100 subunits, sharing 60% sequence identity, have been described as S-100Ï« chain and S-100ÉÇ chain. Three S-100 dimeric forms have been characterized, differing in their subunit composition of either two Ï« chains, two ÉÇ chains or one Ï« and one ÉÇ chain.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of S100 ¦Á (A18) pAb at 1:500 dilutionLane1:HEK293T cell lysateLane2:Mouse brain tissue lysateLane3:Rat brain tissue lysate