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Western blot
Immunocytochemistry
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [36]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- ABIN152468 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Tachykinin Receptor 1 (TACR1) (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- N-Term
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Up-regulated expression of substance P in CD8+ T cells and NK1R on monocytes of atopic dermatitis.
Targeting tachykinin receptors in neuroblastoma.
Effect of truncated neurokinin-1 receptor expression changes on the interaction between human breast cancer and bone marrow-derived mesenchymal stem cells.
Expression of Mas-related gene X2 on mast cells is upregulated in the skin of patients with severe chronic urticaria.
Substance P enhances HIV-1 infection in human fetal brain cell cultures expressing full-length neurokinin-1 receptor.
Roles of full-length and truncated neurokinin-1 receptors on tumor progression and distant metastasis in human breast cancer.
Kinetics of neuronal contribution during the development of a contact allergic reaction.
Visceral hypersensitivity in symptomatic diverticular disease and the role of neuropeptides and low grade inflammation.
GABA(A) Receptor β3 Subunit Expression Regulates Tonic Current in Developing Striatopallidal Medium Spiny Neurons.
Cardiac damage after lesions of the nucleus tractus solitarii.
Presence of substance P and the neurokinin-1 receptor in tenocytes of the human Achilles tendon.
The fate of the large striatal interneurons expressing calretinin in Huntington's disease.
cGMP produced by NO-sensitive guanylyl cyclase essentially contributes to inflammatory and neuropathic pain by using targets different from cGMP-dependent protein kinase I.
Observations favouring the occurrence of local production and marked effects of bombesin/gastrin-releasing peptide in the synovial tissue of the human knee joint--comparisons with substance P and the NK-1 receptor.
Nerve-related characteristics of ventral paratendinous tissue in chronic Achilles tendinosis.
New insight into the role of the beta3 subunit of the GABAA-R in development, behavior, body weight regulation, and anesthesia revealed by conditional gene knockout.
Neurokinin-1 and neurokinin-3 receptors in primate substantia nigra.
Spantide I decreases type I cytokines, enhances IL-10, and reduces corneal perforation in susceptible mice after Pseudomonas aeruginosa infection.
Neurokinin-1 receptor activation in Botzinger complex evokes bradypnoea.
An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice.
Cellular and subcellular localization of neurokinin-1 and neurokinin-3 receptors in primate globus pallidus.
Full-length and truncated neurokinin-1 receptor expression and function during monocyte/macrophage differentiation.
Substance P and the neurokinin-1 receptor in relation to eosinophilia in ulcerative colitis.
Vascular NK-1 receptor occurrence in normal and chronic painful Achilles and patellar tendons: studies on chemically unfixed as well as fixed specimens.
Expression of the NK-1 receptor on islet cells and invading immune cells in the non-obese diabetic mouse.
Depletion of ventromedullary NK-1 receptor-immunoreactive neurons in multiple system atrophy.
Increased tachykinin NK(1) receptor immunoreactivity in the prefrontal cortex in schizophrenia.
NK-1 receptor gene expression is related to pain in chronic pancreatitis.
Localisation of tachykinin NK1 and NK3 receptors in the human prefrontal and visual cortex.
Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor.
Noxious cutaneous thermal stimuli induce a graded release of endogenous substance P in the spinal cord: imaging peptide action in vivo.
Substance P activation of enteric neurons in response to intraluminal Clostridium difficile toxin A in the rat ileum.
Differential expression of two isoforms of the neurokinin-1 (substance P) receptor in vivo.
Rapid endocytosis of a G protein-coupled receptor: substance P evoked internalization of its receptor in the rat striatum in vivo.
Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation.
Characterization of antibodies to the rat substance P (NK-1) receptor and to a chimeric substance P receptor expressed in mammalian cells.
Zhang Z, Zheng W, Xie H, Chai R, Wang J, Zhang H, He S
Journal of translational medicine 2017 May 1;15(1):93
Journal of translational medicine 2017 May 1;15(1):93
Targeting tachykinin receptors in neuroblastoma.
Henssen AG, Odersky A, Szymansky A, Seiler M, Althoff K, Beckers A, Speleman F, Schäfers S, De Preter K, Astrahanseff K, Struck J, Schramm A, Eggert A, Bergmann A, Schulte JH
Oncotarget 2017 Jan 3;8(1):430-443
Oncotarget 2017 Jan 3;8(1):430-443
Effect of truncated neurokinin-1 receptor expression changes on the interaction between human breast cancer and bone marrow-derived mesenchymal stem cells.
Zhou Y, Zuo D, Wang M, Zhang Y, Yu M, Yang J, Yao Z
Genes to cells : devoted to molecular & cellular mechanisms 2014 Sep;19(9):676-91
Genes to cells : devoted to molecular & cellular mechanisms 2014 Sep;19(9):676-91
Expression of Mas-related gene X2 on mast cells is upregulated in the skin of patients with severe chronic urticaria.
Fujisawa D, Kashiwakura J, Kita H, Kikukawa Y, Fujitani Y, Sasaki-Sakamoto T, Kuroda K, Nunomura S, Hayama K, Terui T, Ra C, Okayama Y
The Journal of allergy and clinical immunology 2014 Sep;134(3):622-633.e9
The Journal of allergy and clinical immunology 2014 Sep;134(3):622-633.e9
Substance P enhances HIV-1 infection in human fetal brain cell cultures expressing full-length neurokinin-1 receptor.
Schwartz L, Spitsin SV, Meshki J, Tuluc F, Douglas SD, Wolfe JH
Journal of neurovirology 2013 Jun;19(3):219-27
Journal of neurovirology 2013 Jun;19(3):219-27
Roles of full-length and truncated neurokinin-1 receptors on tumor progression and distant metastasis in human breast cancer.
Zhou Y, Zhao L, Xiong T, Chen X, Zhang Y, Yu M, Yang J, Yao Z
Breast cancer research and treatment 2013 Jul;140(1):49-61
Breast cancer research and treatment 2013 Jul;140(1):49-61
Kinetics of neuronal contribution during the development of a contact allergic reaction.
Altawil R, Lyström J, El-Nour H
Archives of dermatological research 2012 May;304(4):273-81
Archives of dermatological research 2012 May;304(4):273-81
Visceral hypersensitivity in symptomatic diverticular disease and the role of neuropeptides and low grade inflammation.
Humes DJ, Simpson J, Smith J, Sutton P, Zaitoun A, Bush D, Bennett A, Scholefield JH, Spiller RC
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2012 Apr;24(4):318-e163
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2012 Apr;24(4):318-e163
GABA(A) Receptor β3 Subunit Expression Regulates Tonic Current in Developing Striatopallidal Medium Spiny Neurons.
Janssen MJ, Yasuda RP, Vicini S
Frontiers in cellular neuroscience 2011;5:15
Frontiers in cellular neuroscience 2011;5:15
Cardiac damage after lesions of the nucleus tractus solitarii.
Nayate A, Moore SA, Weiss R, Taktakishvili OM, Lin LH, Talman WT
American journal of physiology. Regulatory, integrative and comparative physiology 2009 Feb;296(2):R272-9
American journal of physiology. Regulatory, integrative and comparative physiology 2009 Feb;296(2):R272-9
Presence of substance P and the neurokinin-1 receptor in tenocytes of the human Achilles tendon.
Andersson G, Danielson P, Alfredson H, Forsgren S
Regulatory peptides 2008 Oct 9;150(1-3):81-7
Regulatory peptides 2008 Oct 9;150(1-3):81-7
The fate of the large striatal interneurons expressing calretinin in Huntington's disease.
Massouh M, Wallman MJ, Pourcher E, Parent A
Neuroscience research 2008 Dec;62(4):216-24
Neuroscience research 2008 Dec;62(4):216-24
cGMP produced by NO-sensitive guanylyl cyclase essentially contributes to inflammatory and neuropathic pain by using targets different from cGMP-dependent protein kinase I.
Schmidtko A, Gao W, König P, Heine S, Motterlini R, Ruth P, Schlossmann J, Koesling D, Niederberger E, Tegeder I, Friebe A, Geisslinger G
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Aug 20;28(34):8568-76
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Aug 20;28(34):8568-76
Observations favouring the occurrence of local production and marked effects of bombesin/gastrin-releasing peptide in the synovial tissue of the human knee joint--comparisons with substance P and the NK-1 receptor.
Grimsholm O, Rantapää-Dahlqvist S, Dalén T, Forsgren S
Neuropeptides 2008 Apr;42(2):133-45
Neuropeptides 2008 Apr;42(2):133-45
Nerve-related characteristics of ventral paratendinous tissue in chronic Achilles tendinosis.
Andersson G, Danielson P, Alfredson H, Forsgren S
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA 2007 Oct;15(10):1272-9
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA 2007 Oct;15(10):1272-9
New insight into the role of the beta3 subunit of the GABAA-R in development, behavior, body weight regulation, and anesthesia revealed by conditional gene knockout.
Ferguson C, Hardy SL, Werner DF, Hileman SM, Delorey TM, Homanics GE
BMC neuroscience 2007 Oct 10;8:85
BMC neuroscience 2007 Oct 10;8:85
Neurokinin-1 and neurokinin-3 receptors in primate substantia nigra.
Lévesque M, Wallman MJ, Parent R, Sík A, Parent A
Neuroscience research 2007 Mar;57(3):362-71
Neuroscience research 2007 Mar;57(3):362-71
Spantide I decreases type I cytokines, enhances IL-10, and reduces corneal perforation in susceptible mice after Pseudomonas aeruginosa infection.
Hazlett LD, McClellan SA, Barrett RP, Liu J, Zhang Y, Lighvani S
Investigative ophthalmology & visual science 2007 Feb;48(2):797-807
Investigative ophthalmology & visual science 2007 Feb;48(2):797-807
Neurokinin-1 receptor activation in Botzinger complex evokes bradypnoea.
Fong AY, Potts JT
The Journal of physiology 2006 Sep 15;575(Pt 3):869-85
The Journal of physiology 2006 Sep 15;575(Pt 3):869-85
An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice.
Borghese CM, Werner DF, Topf N, Baron NV, Henderson LA, Boehm SL 2nd, Blednov YA, Saad A, Dai S, Pearce RA, Harris RA, Homanics GE, Harrison NL
The Journal of pharmacology and experimental therapeutics 2006 Oct;319(1):208-18
The Journal of pharmacology and experimental therapeutics 2006 Oct;319(1):208-18
Cellular and subcellular localization of neurokinin-1 and neurokinin-3 receptors in primate globus pallidus.
Lévesque M, Parent R, Parent A
The European journal of neuroscience 2006 May;23(10):2760-72
The European journal of neuroscience 2006 May;23(10):2760-72
Full-length and truncated neurokinin-1 receptor expression and function during monocyte/macrophage differentiation.
Lai JP, Ho WZ, Kilpatrick LE, Wang X, Tuluc F, Korchak HM, Douglas SD
Proceedings of the National Academy of Sciences of the United States of America 2006 May 16;103(20):7771-6
Proceedings of the National Academy of Sciences of the United States of America 2006 May 16;103(20):7771-6
Substance P and the neurokinin-1 receptor in relation to eosinophilia in ulcerative colitis.
Jönsson M, Norrgård O, Forsgren S
Peptides 2005 May;26(5):799-814
Peptides 2005 May;26(5):799-814
Vascular NK-1 receptor occurrence in normal and chronic painful Achilles and patellar tendons: studies on chemically unfixed as well as fixed specimens.
Forsgren S, Danielson P, Alfredson H
Regulatory peptides 2005 Mar 30;126(3):173-81
Regulatory peptides 2005 Mar 30;126(3):173-81
Expression of the NK-1 receptor on islet cells and invading immune cells in the non-obese diabetic mouse.
Persson-Sjögren S, Lejon K, Holmberg D, Forsgren S
Journal of autoimmunity 2005 Jun;24(4):269-79
Journal of autoimmunity 2005 Jun;24(4):269-79
Depletion of ventromedullary NK-1 receptor-immunoreactive neurons in multiple system atrophy.
Benarroch EE, Schmeichel AM, Low PA, Parisi JE
Brain : a journal of neurology 2003 Oct;126(Pt 10):2183-90
Brain : a journal of neurology 2003 Oct;126(Pt 10):2183-90
Increased tachykinin NK(1) receptor immunoreactivity in the prefrontal cortex in schizophrenia.
Tooney PA, Crawter VC, Chahl LA
Biological psychiatry 2001 Mar 15;49(6):523-7
Biological psychiatry 2001 Mar 15;49(6):523-7
NK-1 receptor gene expression is related to pain in chronic pancreatitis.
Shrikhande SV, Friess H, di Mola FF, Tempia-Caliera A, Conejo Garcia JR, Zhu Z, Zimmermann A, Büchler MW
Pain 2001 Apr;91(3):209-17
Pain 2001 Apr;91(3):209-17
Localisation of tachykinin NK1 and NK3 receptors in the human prefrontal and visual cortex.
Tooney PA, Au GG, Chahl LA
Neuroscience letters 2000 Apr 14;283(3):185-8
Neuroscience letters 2000 Apr 14;283(3):185-8
Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor.
Mantyh PW, Rogers SD, Honore P, Allen BJ, Ghilardi JR, Li J, Daughters RS, Lappi DA, Wiley RG, Simone DA
Science (New York, N.Y.) 1997 Oct 10;278(5336):275-9
Science (New York, N.Y.) 1997 Oct 10;278(5336):275-9
Noxious cutaneous thermal stimuli induce a graded release of endogenous substance P in the spinal cord: imaging peptide action in vivo.
Allen BJ, Rogers SD, Ghilardi JR, Menning PM, Kuskowski MA, Basbaum AI, Simone DA, Mantyh PW
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997 Aug 1;17(15):5921-7
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997 Aug 1;17(15):5921-7
Substance P activation of enteric neurons in response to intraluminal Clostridium difficile toxin A in the rat ileum.
Mantyh CR, Pappas TN, Lapp JA, Washington MK, Neville LM, Ghilardi JR, Rogers SD, Mantyh PW, Vigna SR
Gastroenterology 1996 Nov;111(5):1272-80
Gastroenterology 1996 Nov;111(5):1272-80
Differential expression of two isoforms of the neurokinin-1 (substance P) receptor in vivo.
Mantyh PW, Rogers SD, Ghilardi JR, Maggio JE, Mantyh CR, Vigna SR
Brain research 1996 May 6;719(1-2):8-13
Brain research 1996 May 6;719(1-2):8-13
Rapid endocytosis of a G protein-coupled receptor: substance P evoked internalization of its receptor in the rat striatum in vivo.
Mantyh PW, Allen CJ, Ghilardi JR, Rogers SD, Mantyh CR, Liu H, Basbaum AI, Vigna SR, Maggio JE
Proceedings of the National Academy of Sciences of the United States of America 1995 Mar 28;92(7):2622-6
Proceedings of the National Academy of Sciences of the United States of America 1995 Mar 28;92(7):2622-6
Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation.
Mantyh PW, DeMaster E, Malhotra A, Ghilardi JR, Rogers SD, Mantyh CR, Liu H, Basbaum AI, Vigna SR, Maggio JE
Science (New York, N.Y.) 1995 Jun 16;268(5217):1629-32
Science (New York, N.Y.) 1995 Jun 16;268(5217):1629-32
Characterization of antibodies to the rat substance P (NK-1) receptor and to a chimeric substance P receptor expressed in mammalian cells.
Vigna SR, Bowden JJ, McDonald DM, Fisher J, Okamoto A, McVey DC, Payan DG, Bunnett NW
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994 Feb;14(2):834-45
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994 Feb;14(2):834-45
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
