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Learn13585-1-AP
antibody from Proteintech Group
Targeting: PRDX6
1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 13585-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13585-1-AP, RRID:AB_2168637
- Product name
- PRDX6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PRDX6 antibody (Cat. #13585-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identification of a Novel Ferroptosis-Related Gene Prognostic Signature in Bladder Cancer.
Hypothermic oxygenated perfusion with defatting cocktail further improves steatotic liver grafts in a transplantation rat model.
Suppression of mitochondrial ROS by prohibitin drives glioblastoma progression and therapeutic resistance.
Chronic angiotensin receptor activation promotes hepatic triacylglycerol accumulation during an acute glucose challenge in obese-insulin-resistant OLETF rats.
Peroxiredoxins are involved in the pathogenesis of multiple sclerosis and neuromyelitis optica spectrum disorder.
Novel [1,2,3]triazolo[4,5-d]pyrimidine derivatives containing hydrazone fragment as potent and selective anticancer agents.
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Identification of PRDX6 as a regulator of ferroptosis.
The role of cytochrome P450 2E1 on ethanol-mediated oxidative stress and HIV replication in human monocyte-derived macrophages.
4-tert-octylphenol injures motility and viability of human sperm by affecting cAMP-PKA/PKC-tyrosine phosphorylation signals.
Luteolin ameliorates rat myocardial ischaemia-reperfusion injury through activation of peroxiredoxin II.
Nucleophosmin Regulates Intracellular Oxidative Stress Homeostasis via Antioxidant PRDX6.
Peroxiredoxin 6 Is a Crucial Factor in the Initial Step of Mitochondrial Clearance and Is Upstream of the PINK1-Parkin Pathway.
Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs.
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
Sun J, Yue W, You J, Wei X, Huang Y, Ling Z, Hou J
Frontiers in oncology 2021;11:730716
Frontiers in oncology 2021;11:730716
Hypothermic oxygenated perfusion with defatting cocktail further improves steatotic liver grafts in a transplantation rat model.
Lin F, Zhen F, Yan X, Shaojun Y, Guizhu P, Yanfeng W, Qifa Y
Artificial organs 2021 Sep;45(9):E304-E316
Artificial organs 2021 Sep;45(9):E304-E316
Suppression of mitochondrial ROS by prohibitin drives glioblastoma progression and therapeutic resistance.
Huang H, Zhang S, Li Y, Liu Z, Mi L, Cai Y, Wang X, Chen L, Ran H, Xiao D, Li F, Wu J, Li T, Han Q, Chen L, Pan X, Li H, Li T, He K, Li A, Zhang X, Zhou T, Xia Q, Man J
Nature communications 2021 Jun 17;12(1):3720
Nature communications 2021 Jun 17;12(1):3720
Chronic angiotensin receptor activation promotes hepatic triacylglycerol accumulation during an acute glucose challenge in obese-insulin-resistant OLETF rats.
Godoy-Lugo JA, Thorwald MA, Hui DY, Nishiyama A, Nakano D, Soñanez-Organis JG, Ortiz RM
Endocrine 2021 Jul 29;
Endocrine 2021 Jul 29;
Peroxiredoxins are involved in the pathogenesis of multiple sclerosis and neuromyelitis optica spectrum disorder.
Uzawa A, Mori M, Masuda H, Ohtani R, Uchida T, Aoki R, Kuwabara S
Clinical and experimental immunology 2020 Nov;202(2):239-248
Clinical and experimental immunology 2020 Nov;202(2):239-248
Novel [1,2,3]triazolo[4,5-d]pyrimidine derivatives containing hydrazone fragment as potent and selective anticancer agents.
Xu C, Zhou W, Dong G, Qiao H, Peng J, Jia P, Li Y, Liu H, Sun K, Zhao W
Bioorganic chemistry 2020 Dec;105:104424
Bioorganic chemistry 2020 Dec;105:104424
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Ma Z, Lu Y, Yang F, Li S, He X, Gao Y, Zhang G, Ren E, Wang Y, Kang X
Toxicology and applied pharmacology 2020 Apr 19;397:115014
Toxicology and applied pharmacology 2020 Apr 19;397:115014
Identification of PRDX6 as a regulator of ferroptosis.
Lu B, Chen XB, Hong YC, Zhu H, He QJ, Yang B, Ying MD, Cao J
Acta pharmacologica Sinica 2019 Oct;40(10):1334-1342
Acta pharmacologica Sinica 2019 Oct;40(10):1334-1342
The role of cytochrome P450 2E1 on ethanol-mediated oxidative stress and HIV replication in human monocyte-derived macrophages.
Gong Y, Rao PSS, Sinha N, Ranjit S, Cory TJ, Kumar S
Biochemistry and biophysics reports 2019 Mar;17:65-70
Biochemistry and biophysics reports 2019 Mar;17:65-70
4-tert-octylphenol injures motility and viability of human sperm by affecting cAMP-PKA/PKC-tyrosine phosphorylation signals.
Huang S, Cao S, Zhou T, Kong L, Liang G
Environmental toxicology and pharmacology 2018 Sep;62:234-243
Environmental toxicology and pharmacology 2018 Sep;62:234-243
Luteolin ameliorates rat myocardial ischaemia-reperfusion injury through activation of peroxiredoxin II.
Wei B, Lin Q, Ji YG, Zhao YC, Ding LN, Zhou WJ, Zhang LH, Gao CY, Zhao W
British journal of pharmacology 2018 Aug;175(16):3315-3332
British journal of pharmacology 2018 Aug;175(16):3315-3332
Nucleophosmin Regulates Intracellular Oxidative Stress Homeostasis via Antioxidant PRDX6.
Liu GY, Shi JX, Shi SL, Liu F, Rui G, Li X, Gao LB, Deng XL, Li QF
Journal of cellular biochemistry 2017 Dec;118(12):4697-4707
Journal of cellular biochemistry 2017 Dec;118(12):4697-4707
Peroxiredoxin 6 Is a Crucial Factor in the Initial Step of Mitochondrial Clearance and Is Upstream of the PINK1-Parkin Pathway.
Ma S, Zhang X, Zheng L, Li Z, Zhao X, Lai W, Shen H, Lv J, Yang G, Wang Q, Ji J
Antioxidants & redox signaling 2016 Mar 20;24(9):486-501
Antioxidants & redox signaling 2016 Mar 20;24(9):486-501
Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs.
Sahu N, Stephan JP, Cruz DD, Merchant M, Haley B, Bourgon R, Classon M, Settleman J
Nature communications 2016 Aug 3;7:12351
Nature communications 2016 Aug 3;7:12351
MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.
Aras S, Bai M, Lee I, Springett R, Hüttemann M, Grossman LI
Mitochondrion 2015 Jan;20:43-51
Mitochondrion 2015 Jan;20:43-51
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A549 cells were subjected to SDS PAGE followed by western blot with 13585-1-AP(PRDX6 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using PRDX6 antibody 13585-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 13585-1-AP(PRDX6 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 13585-1-AP(PRDX6 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
