BS7704

antibody from Bioworld Technology, Inc

Targeting: S100A7 PSOR1, S100A7c

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS7704

Provider

Bioworld Technology, Inc

Product name

S100A7 polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant full length Human S100A7.

Description

S100A7 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein functions as a prominent antimicrobial peptide mainly against E. coli. S100A7 also displays antimicrobial properties. It is secreted by epithilial cells of the skin and is a key antimicrobial protein against Escherichia Coli by disrupting their cell membranes. This is the reason that in countries with poor sanitation,human skin is exposed E.coli strains from faecal matter but it does not usually result in an infection. S100A7 is highly homologous to S100A15 (koebnerisin) but distinct in expression, tissue distribution and function.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.