Antibody data

Product number
10-7550-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-Galectin 13 Antibody
Antibody type
Monoclonal
Description
Galectin-13 (Gal-13) is a glycan-binding protein that regulates innate and adaptive immune responses. It is predominantly expressed by the syncytiotrophoblast and released from the placenta into the maternal circulation. It has the ability to induce apoptosis of activated T cells in vitro, and divert and kill T cells as well as macrophages in the maternal decidua. Gal-13 with its anti-inflammatory functions plays a role in regulation of maternal immune system, a lack of gal-13 contribute to an imbalance in inflammation processes in the placenta during pregnancy and therefore influences development of gestational diabetes mellitus (GDM). Gal-13 levels are low in the first trimester of pregnancy that confers a higher risk for developing pre-eclampsia later in pregnancy.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
A full length human Galectin-13 pro
tein was used as the immunogen for
this antibody.
Isotype
IgG
Antibody clone number
ABM4E42
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
LGALS13 protein structure - 10-7550-25 shown in red.