Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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- Product number
- ALX-804-439-R100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-804-439-R100, RRID:AB_2051424
- Product name
- Folate receptor _ monoclonal antibody (Mov18)
- Antibody type
- Monoclonal
- Antigen
- Purified from natural sources
- Description
- Purified from concentrated hybridoma cell culture supernatant.
- Reactivity
- Human, Simian
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- Mov18
- Vial size
- 100 μl
- Storage
- +4°C
- Handling
- Avoid freeze/thaw cycles.
Submitted references Folic acid mediates activation of the pro-oncogene STAT3 via the Folate Receptor alpha.
Expression of folate transporters in human placenta and implications for homocysteine metabolism.
Folate receptor alpha defect causes cerebral folate transport deficiency: a treatable neurodegenerative disorder associated with disturbed myelin metabolism.
Functional folate receptor alpha is elevated in the blood of ovarian cancer patients.
Targeting of porous hybrid silica nanoparticles to cancer cells.
Immunological profiling of a panel of human ovarian cancer cell lines.
Molecular requirements for attachment of the glycosylphosphatidylinositol anchor to the human alpha folate receptor.
Role of folate receptor and reduced folate carrier in the transport of 5-methyltetrahydrofolic acid in human ovarian carcinoma cells.
Folate binding protein distribution in normal tissues and biological fluids from ovarian carcinoma patients as detected by the monoclonal antibodies MOv18 and MOv19.
Effect of hydrostatic pressure and cholesterol depletion on the expression of a tumor-associated antigen.
Isolation and biochemical characterization of the soluble and membrane forms of folate binding protein expressed in the ovarian carcinoma cell line IGROV1.
Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues.
Cloning of a tumor-associated antigen: MOv18 and MOv19 antibodies recognize a folate-binding protein.
Characterization of human ovarian carcinoma-associated antigens defined by novel monoclonal antibodies with tumor-restricted specificity.
Hansen MF, Greibe E, Skovbjerg S, Rohde S, Kristensen AC, Jensen TR, Stentoft C, Kjær KH, Kronborg CS, Martensen PM
Cellular signalling 2015 Jul;27(7):1356-68
Cellular signalling 2015 Jul;27(7):1356-68
Expression of folate transporters in human placenta and implications for homocysteine metabolism.
Solanky N, Requena Jimenez A, D'Souza SW, Sibley CP, Glazier JD
Placenta 2010 Feb;31(2):134-43
Placenta 2010 Feb;31(2):134-43
Folate receptor alpha defect causes cerebral folate transport deficiency: a treatable neurodegenerative disorder associated with disturbed myelin metabolism.
Steinfeld R, Grapp M, Kraetzner R, Dreha-Kulaczewski S, Helms G, Dechent P, Wevers R, Grosso S, Gärtner J
American journal of human genetics 2009 Sep;85(3):354-63
American journal of human genetics 2009 Sep;85(3):354-63
Functional folate receptor alpha is elevated in the blood of ovarian cancer patients.
Basal E, Eghbali-Fatourechi GZ, Kalli KR, Hartmann LC, Goodman KM, Goode EL, Kamen BA, Low PS, Knutson KL
PloS one 2009 Jul 20;4(7):e6292
PloS one 2009 Jul 20;4(7):e6292
Targeting of porous hybrid silica nanoparticles to cancer cells.
Rosenholm JM, Meinander A, Peuhu E, Niemi R, Eriksson JE, Sahlgren C, Lindén M
ACS nano 2009 Jan 27;3(1):197-206
ACS nano 2009 Jan 27;3(1):197-206
Immunological profiling of a panel of human ovarian cancer cell lines.
Carr TM, Adair SJ, Fink MJ, Hogan KT
Cancer immunology, immunotherapy : CII 2008 Jan;57(1):31-42
Cancer immunology, immunotherapy : CII 2008 Jan;57(1):31-42
Molecular requirements for attachment of the glycosylphosphatidylinositol anchor to the human alpha folate receptor.
Tomassetti A, Bottero F, Mazzi M, Miotti S, Colnaghi MI, Canevari S
Journal of cellular biochemistry 1999 Jan 1;72(1):111-8
Journal of cellular biochemistry 1999 Jan 1;72(1):111-8
Role of folate receptor and reduced folate carrier in the transport of 5-methyltetrahydrofolic acid in human ovarian carcinoma cells.
Corona G, Giannini F, Fabris M, Toffoli G, Boiocchi M
International journal of cancer 1998 Jan 5;75(1):125-33
International journal of cancer 1998 Jan 5;75(1):125-33
Folate binding protein distribution in normal tissues and biological fluids from ovarian carcinoma patients as detected by the monoclonal antibodies MOv18 and MOv19.
Mantovani LT, Miotti S, Ménard S, Canevari S, Raspagliesi F, Bottini C, Bottero F, Colnaghi MI
European journal of cancer (Oxford, England : 1990) 1994;30A(3):363-9
European journal of cancer (Oxford, England : 1990) 1994;30A(3):363-9
Effect of hydrostatic pressure and cholesterol depletion on the expression of a tumor-associated antigen.
Gesmundo N, Calonghi N, Sartor G, Farruggia G, Miotti S, Canevari S, Colnaghi MI, Masotti L
European journal of biochemistry / FEBS 1993 Oct 1;217(1):337-43
European journal of biochemistry / FEBS 1993 Oct 1;217(1):337-43
Isolation and biochemical characterization of the soluble and membrane forms of folate binding protein expressed in the ovarian carcinoma cell line IGROV1.
Tomassetti A, Coney LR, Canevari S, Miotti S, Facheris P, Zurawski VR Jr, Colnaghi MI
FEBS letters 1993 Feb 8;317(1-2):143-6
FEBS letters 1993 Feb 8;317(1-2):143-6
Distribution of the folate receptor GP38 in normal and malignant cell lines and tissues.
Weitman SD, Lark RH, Coney LR, Fort DW, Frasca V, Zurawski VR Jr, Kamen BA
Cancer research 1992 Jun 15;52(12):3396-401
Cancer research 1992 Jun 15;52(12):3396-401
Cloning of a tumor-associated antigen: MOv18 and MOv19 antibodies recognize a folate-binding protein.
Coney LR, Tomassetti A, Carayannopoulos L, Frasca V, Kamen BA, Colnaghi MI, Zurawski VR Jr
Cancer research 1991 Nov 15;51(22):6125-32
Cancer research 1991 Nov 15;51(22):6125-32
Characterization of human ovarian carcinoma-associated antigens defined by novel monoclonal antibodies with tumor-restricted specificity.
Miotti S, Canevari S, Ménard S, Mezzanzanica D, Porro G, Pupa SM, Regazzoni M, Tagliabue E, Colnaghi MI
International journal of cancer 1987 Mar 15;39(3):297-303
International journal of cancer 1987 Mar 15;39(3):297-303
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Supportive validation
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- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Figures: Immunoperoxidase staining of acetone-fixed cryostatic sections from a human serous ovary carcinoma at low (A) and high (B) magnification showing membrane localization.