FNab04225

antibody from FineTest Biotech
Targeting: IL17A CTLA8, IL-17, IL-17A, IL17
Provider product page for FNab04225
Western blot
ELISA
Flow cytometry

Antibody data

Product number
FNab04225 - Provider product page
Provider
FineTest Biotech
Product name
IL-17 antibody
Antibody type
Monoclonal
Antigen
Recombinant protein fragment
Description
IL17A, also named as IL-17, is a proinflammatory cytokine. IL-17, synthesized only by memory T cells and natural killer cells, has pleiotropic effects, mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2(PTGS2/COX-2), as well as enhance the production of nitric oxide(NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The IL-17 receptor is a type I transmembrane protein, that is widely expressed on epithelial cells, fibroblasts, B and T cells, and monocytic cells. In psoriatic skin lesions, both Th17 cells and their downstream effector molecules, e.g. IL-17 and IL-22, are highly increased.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
interleukin 17A
Epitope
IgG1
Isotype
IgG
Antibody clone number
500
Vial size
100¦Ìg
Concentration
Protein A+G purification
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
IL17A protein structure - FNab04225 shown in red.