Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 11746-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11746-1-AP, RRID:AB_2247970
- Product name
- HBP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HBP1 antibody (Cat. #11746-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CRISPR interference and activation of the microRNA-3662-HBP1 axis control progression of triple-negative breast cancer.
miR-29c&b2 encourage extramedullary infiltration resulting in the poor prognosis of acute myeloid leukemia.
HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.
MDM2 promotes genome instability by ubiquitinating the transcription factor HBP1.
Transcription factor HMG box-containing protein 1 (HBP1) modulates mitotic clonal expansion (MCE) during adipocyte differentiation.
A positive feedback loop between Pim-1 kinase and HBP1 transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis.
HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis.
MYC through miR-17-92 suppresses specific target genes to maintain survival, autonomous proliferation, and a neoplastic state.
HBP1-mediated transcriptional regulation of DNA methyltransferase 1 and its impact on cell senescence.
Yi B, Wang S, Wang X, Liu Z, Zhang C, Li M, Gao S, Wei S, Bae S, Stringer-Reasor E, Wang L, Liu R
Oncogene 2022 Jan;41(2):268-279
Oncogene 2022 Jan;41(2):268-279
miR-29c&b2 encourage extramedullary infiltration resulting in the poor prognosis of acute myeloid leukemia.
Wei Y, Lu W, Yu Y, Zhai Y, Guo H, Yang S, Zhao C, Zhang Y, Liu J, Liu Y, Fei J, Shi J
Oncogene 2021 May;40(19):3434-3448
Oncogene 2021 May;40(19):3434-3448
HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.
Cao Z, Cheng Y, Wang J, Liu Y, Yang R, Jiang W, Li H, Zhang X
Journal of experimental & clinical cancer research : CR 2021 Apr 1;40(1):118
Journal of experimental & clinical cancer research : CR 2021 Apr 1;40(1):118
MDM2 promotes genome instability by ubiquitinating the transcription factor HBP1.
Cao Z, Xue J, Cheng Y, Wang J, Liu Y, Li H, Jiang W, Li G, Gui Y, Zhang X
Oncogene 2019 Jun;38(24):4835-4855
Oncogene 2019 Jun;38(24):4835-4855
Transcription factor HMG box-containing protein 1 (HBP1) modulates mitotic clonal expansion (MCE) during adipocyte differentiation.
Chan CY, Yu P, Chang FT, Chen ZH, Lee MF, Huang CY
Journal of cellular physiology 2018 May;233(5):4205-4215
Journal of cellular physiology 2018 May;233(5):4205-4215
A positive feedback loop between Pim-1 kinase and HBP1 transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis.
Wang S, Cao Z, Xue J, Li H, Jiang W, Cheng Y, Li G, Zhang X
The Journal of biological chemistry 2017 May 19;292(20):8207-8222
The Journal of biological chemistry 2017 May 19;292(20):8207-8222
HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis.
Chen Y, Pan K, Wang P, Cao Z, Wang W, Wang S, Hu N, Xue J, Li H, Jiang W, Li G, Zhang X
The Journal of biological chemistry 2016 Jun 10;291(24):12688-12705
The Journal of biological chemistry 2016 Jun 10;291(24):12688-12705
MYC through miR-17-92 suppresses specific target genes to maintain survival, autonomous proliferation, and a neoplastic state.
Li Y, Choi PS, Casey SC, Dill DL, Felsher DW
Cancer cell 2014 Aug 11;26(2):262-72
Cancer cell 2014 Aug 11;26(2):262-72
HBP1-mediated transcriptional regulation of DNA methyltransferase 1 and its impact on cell senescence.
Pan K, Chen Y, Roth M, Wang W, Wang S, Yee AS, Zhang X
Molecular and cellular biology 2013 Mar;33(5):887-903
Molecular and cellular biology 2013 Mar;33(5):887-903
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The HBP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HBP1. This antibody recognizes human antigen. The HBP1 antibody has been validated for the following applications: ELISA, WB analysis.