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- References [5]
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- Western blot [1]
- Flow cytometry [1]
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- Product number
- NB100-1269 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-1269, RRID:AB_2105152
- Product name
- Goat Polyclonal FoxC2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse
- Host
- Goat
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Foxc1 is required by pericytes during fetal brain angiogenesis.
Cortical dysplasia and skull defects in mice with a Foxc1 allele reveal the role of meningeal differentiation in regulating cortical development.
Foxc2 is expressed in developing lymphatic vessels and other tissues associated with lymphedema-distichiasis syndrome.
Analysis of the phenotypic abnormalities in lymphoedema-distichiasis syndrome in 74 patients with FOXC2 mutations or linkage to 16q24.
Analysis of the phenotypic abnormalities in lymphoedema-distichiasis syndrome in 74 patients with FOXC2 mutations or linkage to 16q24.
Siegenthaler JA, Choe Y, Patterson KP, Hsieh I, Li D, Jaminet SC, Daneman R, Kume T, Huang EJ, Pleasure SJ
Biology open 2013 Jul 15;2(7):647-59
Biology open 2013 Jul 15;2(7):647-59
Cortical dysplasia and skull defects in mice with a Foxc1 allele reveal the role of meningeal differentiation in regulating cortical development.
Zarbalis K, Siegenthaler JA, Choe Y, May SR, Peterson AS, Pleasure SJ
Proceedings of the National Academy of Sciences of the United States of America 2007 Aug 28;104(35):14002-7
Proceedings of the National Academy of Sciences of the United States of America 2007 Aug 28;104(35):14002-7
Foxc2 is expressed in developing lymphatic vessels and other tissues associated with lymphedema-distichiasis syndrome.
Dagenais SL, Hartsough RL, Erickson RP, Witte MH, Butler MG, Glover TW
Gene expression patterns : GEP 2004 Oct;4(6):611-9
Gene expression patterns : GEP 2004 Oct;4(6):611-9
Analysis of the phenotypic abnormalities in lymphoedema-distichiasis syndrome in 74 patients with FOXC2 mutations or linkage to 16q24.
Brice G, Mansour S, Bell R, Collin JR, Child AH, Brady AF, Sarfarazi M, Burnand KG, Jeffery S, Mortimer P, Murday VA
Journal of medical genetics 2002 Jul;39(7):478-83
Journal of medical genetics 2002 Jul;39(7):478-83
Analysis of the phenotypic abnormalities in lymphoedema-distichiasis syndrome in 74 patients with FOXC2 mutations or linkage to 16q24.
Brice G, Mansour S, Bell R, Collin JR, Child AH, Brady AF, Sarfarazi M, Burnand KG, Jeffery S, Mortimer P, Murday VA
Journal of medical genetics 2002 Jul;39(7):478-83
Journal of medical genetics 2002 Jul;39(7):478-83
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: FoxC2 Antibody [NB100-1269] - Staining of nuclear HEK293 cell lysate with antibody at 2 ug/mL (A) and negative control human pancreas cell lysate with antibody at 1 ug/mL (B) (RIPA buffer 35 ug total protein per lane). Detected by chemiluminescence.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: FoxC2 Antibody [NB100-1269] - Analysis of paraformaldehyde fixed HEK293 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.
