BS7777

antibody from Bioworld Technology, Inc
Targeting: PI3 cementoin, ELAFIN, ESI, SKALP, WAP3, WFDC14
Provider product page for BS7777
Western blot
Immunohistochemistry

Antibody data

Product number
BS7777 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PI3 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PI3.
Description
Elafin, also known as elastase-specific inhibitor (ESI) or skin-derived anti-leukoproteinase (SKALP), is a low molecular weight elastase inhibitor derived from psoriatic skin. Elafin is found in the epidermis of several inflammatory skin diseases, but not in normal human epidermis. It is found in the urine of psoriatic patients, and immunohistochemical studies show that elafin is found in the suprabasal differentiated keratinocytes of psoriatic epidermis. In inflamed skin, elafin exists both as a free form and as an immobilized form covalently attached to the cornified envelopes by transglutaminase cross-linking. Although there is no allelic association between pustular psoriasis (or psoriasis in general) and polymorphism of the PI3 gene, a decrease of elafin is found in lesional skin of patients with pustular psoriasis compared with plaque-type psoriasis.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PI3 protein structure - BS7777 shown in red.