Tissue expression
Cell line expression
Protein structure
USP15
Ubiquitin specific peptidase 15KIAA0529, UNPH4
This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2. [provided by RefSeq, Nov 2011]
Top validated antibodies |
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Novus Biologicals | ![]() |
12 references | Monoclonal |
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Proteintech Group | ![]() |
12 references | Polyclonal |
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Abnova Corporation | ![]() |
9 references | Monoclonal |
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LSBio | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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