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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
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- Product number
- ABIN1881460 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Inhibitor of Growth Family, Member 2 (ING2) (Center), (AA 112-141) antibody
- Antibody type
- Polyclonal
- Antigen
- This ING2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-141 amino acids from the Central region of human ING2.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Center,AA 112-141
- Antibody clone number
- RB40520
- Vial size
- 400 μL
- Concentration
- 0.5 mg/mL
Submitted references Sumoylation of ING2 regulates the transcription mediated by Sin3A.
ING2 is upregulated in colon cancer and increases invasion by enhanced MMP13 expression.
ING2 controls the progression of DNA replication forks to maintain genome stability.
Frequent deletion of ING2 locus at 4q35.1 associates with advanced tumor stage in head and neck squamous cell carcinoma.
A novel ING2 isoform, ING2b, synergizes with ING2a to prevent cell cycle arrest and apoptosis.
Ythier D, Larrieu D, Binet R, Binda O, Brambilla C, Gazzeri S, Pedeux R
Oncogene 2010 Nov 4;29(44):5946-56
Oncogene 2010 Nov 4;29(44):5946-56
ING2 is upregulated in colon cancer and increases invasion by enhanced MMP13 expression.
Kumamoto K, Fujita K, Kurotani R, Saito M, Unoki M, Hagiwara N, Shiga H, Bowman ED, Yanaihara N, Okamura S, Nagashima M, Miyamoto K, Takenoshita S, Yokota J, Harris CC
International journal of cancer. Journal international du cancer 2009 Sep 15;125(6):1306-15
International journal of cancer. Journal international du cancer 2009 Sep 15;125(6):1306-15
ING2 controls the progression of DNA replication forks to maintain genome stability.
Larrieu D, Ythier D, Binet R, Brambilla C, Brambilla E, Sengupta S, Pedeux R
EMBO reports 2009 Oct;10(10):1168-74
EMBO reports 2009 Oct;10(10):1168-74
Frequent deletion of ING2 locus at 4q35.1 associates with advanced tumor stage in head and neck squamous cell carcinoma.
Borkosky SS, Gunduz M, Nagatsuka H, Beder LB, Gunduz E, Ali MA, Rodriguez AP, Cilek MZ, Tominaga S, Yamanaka N, Shimizu K, Nagai N
Journal of cancer research and clinical oncology 2009 May;135(5):703-13
Journal of cancer research and clinical oncology 2009 May;135(5):703-13
A novel ING2 isoform, ING2b, synergizes with ING2a to prevent cell cycle arrest and apoptosis.
Unoki M, Kumamoto K, Robles AI, Shen JC, Zheng ZM, Harris CC
FEBS letters 2008 Nov 26;582(28):3868-74
FEBS letters 2008 Nov 26;582(28):3868-74
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ING2 Antibody (Center) (ABIN1881460) western blot analysis in ZR-75-1 cell line lysates (35 μg/lane). This demonstrates the ING2 antibody detected the ING2 protein (arrow).
