MB0010

antibody from Bioworld Technology, Inc

Targeting: PSME3 Ki, PA28-gamma, PA28G, REG-GAMMA

Antibody data

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Validation data

Product number: MB0010 - Provider product page
Provider: Bioworld Technology, Inc
Product name: PSME3 monoclonal antibody
Antibody type: Monoclonal
Antigen: Recombinant full length Human PSME3.
Description: Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a donut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation.
Reactivity: Human
Host: Mouse
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

PSME3 protein structure - MB0010 shown in red.