11-4016

antibody from ABEOMICS Inc.
Targeting: IFRD1 PC4, TIS7
Provider product page for 11-4016

Antibody data

Product number
11-4016 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-Tis7 Antibody
Antibody type
Polyclonal
Description
Tis7/IFRD1 (interferon-related developmental regulator 1) is expressed by neutrophils as a key modifier gene in cystic fibrosis (CF) lung disease. It functions as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. In skeletal muscle cells, Tis7 is known to function as a coactivator of MyoD by promoting the transcriptional activity of myocyte enhancer factor 2C (MEF2C). Mutations in Tis7 are associated with sensory/motor neuropathy with ataxia.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant Tis7 p
rotein (amino acids 1-300) was used
as the immunogen for this antibody
.
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
IFRD1 protein structure - 11-4016 shown in red.