Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11-4016-25 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-Tis7 Antibody
- Antibody type
- Polyclonal
- Description
- Tis7/IFRD1 (interferon-related developmental regulator 1) is expressed by neutrophils as a key modifier gene in cystic fibrosis (CF) lung disease. It functions as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. In skeletal muscle cells, Tis7 is known to function as a coactivator of MyoD by promoting the transcriptional activity of myocyte enhancer factor 2C (MEF2C). Mutations in Tis7 are associated with sensory/motor neuropathy with ataxia.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant Tis7 p
rotein (amino acids 1-300) was used
as the immunogen for this antibody
.- Vial size
- 25 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of Tis7. Anti-Tis7 antibody (11-4016) was used at 4 µg/ml on Testis lysate.