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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS6223 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- PML polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human PML.
- Description
- The PML protein is a zinc finger transcription factor expressed as three major transcription products due to alternative splicing. The gene encoding human PML maps to chromosome 15q22. The t(15;17) (q22;q11.2-q12) chromosomal trans-location of the retinoic acid receptor Ï« (RARÏ«) gene occurs in virtually all cases of acute promyelocytic leukemia and results in the expression of a PML/RARÏ« chimeric protein. Myeloid precursor cells expressing the PML/ RARÏ« chimera fail to differentiate and exhibit an increased growth rate consequent to diminished apoptosis.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- WesternBlot (WB) analysis of PML pAb in extracts from Hela cells.
