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- References [21]
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- Product number
- ABIN252967 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Promyelocytic Leukemia (PML) (AA 375-425) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 375-425
- Vial size
- 0.1 mL
- Storage
- Store at 4°C. Do not freeze.
- Handling
- Do not freeze.
Submitted references The Arginine/Lysine-Rich Element within the DNA-Binding Domain Is Essential for Nuclear Localization and Function of the Intracellular Pathogen Resistance 1.
Sp100A is a tumor suppressor that activates p53-dependent transcription and counteracts E1A/E1B-55K-mediated transformation.
PML isoforms IV and V contribute to adenovirus-mediated oncogenic transformation by functionally inhibiting the tumor-suppressor p53.
KAP1 Is a Host Restriction Factor That Promotes Human Adenovirus E1B-55K SUMO Modification.
An Adenovirus DNA Replication Factor, but Not Incoming Genome Complexes, Targets PML Nuclear Bodies.
KLHL39 suppresses colon cancer metastasis by blocking KLHL20-mediated PML and DAPK ubiquitination.
Promyelocytic leukemia bodies tether to early endosomes during mitosis.
HIF factors cooperate with PML-RARα to promote acute promyelocytic leukemia progression and relapse.
Sp100 isoform-specific regulation of human adenovirus 5 gene expression.
The adenoviral oncogene E1A-13S interacts with a specific isoform of the tumor suppressor PML to enhance viral transcription.
Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes.
Covalent protein modification with ISG15 via a conserved cysteine in the hinge region.
Interferon-β induces cellular senescence in cutaneous human papilloma virus-transformed human keratinocytes by affecting p53 transactivating activity.
A metabolic prosurvival role for PML in breast cancer.
Functions of the Epstein-Barr virus EBNA1 protein in viral reactivation and lytic infection.
Contributions of the Epstein-Barr virus EBNA1 protein to gastric carcinoma.
Study of early events during herpes simplex virus type 1 infection by confocal microscopy.
Reciprocal regulation of TREK-1 channels by arachidonic acid and CRH in mouse corticotropes.
The alphaherpesvirus serine/threonine kinase us3 disrupts promyelocytic leukemia protein nuclear bodies.
SUMO modification of E1B-55K oncoprotein regulates isoform-specific binding to the tumour suppressor protein PML.
Epstein-Barr virus nuclear antigen 1 Hijacks the host kinase CK2 to disrupt PML nuclear bodies.
Yao K, Wu Y, Chen Q, Zhang Z, Chen X, Zhang Y
PloS one 2016;11(9):e0162832
PloS one 2016;11(9):e0162832
Sp100A is a tumor suppressor that activates p53-dependent transcription and counteracts E1A/E1B-55K-mediated transformation.
Berscheminski J, Brun J, Speiseder T, Wimmer P, Ip WH, Terzic M, Dobner T, Schreiner S
Oncogene 2016 Jun 16;35(24):3178-89
Oncogene 2016 Jun 16;35(24):3178-89
PML isoforms IV and V contribute to adenovirus-mediated oncogenic transformation by functionally inhibiting the tumor-suppressor p53.
Wimmer P, Berscheminski J, Blanchette P, Groitl P, Branton PE, Hay RT, Dobner T, Schreiner S
Oncogene 2016 Jan 7;35(1):69-82
Oncogene 2016 Jan 7;35(1):69-82
KAP1 Is a Host Restriction Factor That Promotes Human Adenovirus E1B-55K SUMO Modification.
Bürck C, Mund A, Berscheminski J, Kieweg L, Müncheberg S, Dobner T, Schreiner S
Journal of virology 2016 Jan 15;90(2):930-46
Journal of virology 2016 Jan 15;90(2):930-46
An Adenovirus DNA Replication Factor, but Not Incoming Genome Complexes, Targets PML Nuclear Bodies.
Komatsu T, Nagata K, Wodrich H
Journal of virology 2016 Feb 1;90(3):1657-67
Journal of virology 2016 Feb 1;90(3):1657-67
KLHL39 suppresses colon cancer metastasis by blocking KLHL20-mediated PML and DAPK ubiquitination.
Chen HY, Hu JY, Chen TH, Lin YC, Liu X, Lin MY, Lang YD, Yen Y, Chen RH
Oncogene 2015 Oct 1;34(40):5141-51
Oncogene 2015 Oct 1;34(40):5141-51
Promyelocytic leukemia bodies tether to early endosomes during mitosis.
Palibrk V, Lång E, Lång A, Schink KO, Rowe AD, Bøe SO
Cell cycle (Georgetown, Tex.) 2014;13(11):1749-55
Cell cycle (Georgetown, Tex.) 2014;13(11):1749-55
HIF factors cooperate with PML-RARα to promote acute promyelocytic leukemia progression and relapse.
Coltella N, Percio S, Valsecchi R, Cuttano R, Guarnerio J, Ponzoni M, Pandolfi PP, Melillo G, Pattini L, Bernardi R
EMBO molecular medicine 2014 May;6(5):640-50
EMBO molecular medicine 2014 May;6(5):640-50
Sp100 isoform-specific regulation of human adenovirus 5 gene expression.
Berscheminski J, Wimmer P, Brun J, Ip WH, Groitl P, Horlacher T, Jaffray E, Hay RT, Dobner T, Schreiner S
Journal of virology 2014 Jun;88(11):6076-92
Journal of virology 2014 Jun;88(11):6076-92
The adenoviral oncogene E1A-13S interacts with a specific isoform of the tumor suppressor PML to enhance viral transcription.
Berscheminski J, Groitl P, Dobner T, Wimmer P, Schreiner S
Journal of virology 2013 Jan;87(2):965-77
Journal of virology 2013 Jan;87(2):965-77
Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes.
Schreiner S, Bürck C, Glass M, Groitl P, Wimmer P, Kinkley S, Mund A, Everett RD, Dobner T
Nucleic acids research 2013 Apr 1;41(6):3532-50
Nucleic acids research 2013 Apr 1;41(6):3532-50
Covalent protein modification with ISG15 via a conserved cysteine in the hinge region.
Bade VN, Nickels J, Keusekotten K, Praefcke GJ
PloS one 2012;7(6):e38294
PloS one 2012;7(6):e38294
Interferon-β induces cellular senescence in cutaneous human papilloma virus-transformed human keratinocytes by affecting p53 transactivating activity.
Chiantore MV, Vannucchi S, Accardi R, Tommasino M, Percario ZA, Vaccari G, Affabris E, Fiorucci G, Romeo G
PloS one 2012;7(5):e36909
PloS one 2012;7(5):e36909
A metabolic prosurvival role for PML in breast cancer.
Carracedo A, Weiss D, Leliaert AK, Bhasin M, de Boer VC, Laurent G, Adams AC, Sundvall M, Song SJ, Ito K, Finley LS, Egia A, Libermann T, Gerhart-Hines Z, Puigserver P, Haigis MC, Maratos-Flier E, Richardson AL, Schafer ZT, Pandolfi PP
The Journal of clinical investigation 2012 Sep;122(9):3088-100
The Journal of clinical investigation 2012 Sep;122(9):3088-100
Functions of the Epstein-Barr virus EBNA1 protein in viral reactivation and lytic infection.
Sivachandran N, Wang X, Frappier L
Journal of virology 2012 Jun;86(11):6146-58
Journal of virology 2012 Jun;86(11):6146-58
Contributions of the Epstein-Barr virus EBNA1 protein to gastric carcinoma.
Sivachandran N, Dawson CW, Young LS, Liu FF, Middeldorp J, Frappier L
Journal of virology 2012 Jan;86(1):60-8
Journal of virology 2012 Jan;86(1):60-8
Study of early events during herpes simplex virus type 1 infection by confocal microscopy.
Everett RD
Methods (San Diego, Calif.) 2011 Oct;55(2):144-52
Methods (San Diego, Calif.) 2011 Oct;55(2):144-52
Reciprocal regulation of TREK-1 channels by arachidonic acid and CRH in mouse corticotropes.
Lee AK, Smart JL, Rubinstein M, Low MJ, Tse A
Endocrinology 2011 May;152(5):1901-10
Endocrinology 2011 May;152(5):1901-10
The alphaherpesvirus serine/threonine kinase us3 disrupts promyelocytic leukemia protein nuclear bodies.
Jung M, Finnen RL, Neron CE, Banfield BW
Journal of virology 2011 Jun;85(11):5301-11
Journal of virology 2011 Jun;85(11):5301-11
SUMO modification of E1B-55K oncoprotein regulates isoform-specific binding to the tumour suppressor protein PML.
Wimmer P, Schreiner S, Everett RD, Sirma H, Groitl P, Dobner T
Oncogene 2010 Oct 7;29(40):5511-22
Oncogene 2010 Oct 7;29(40):5511-22
Epstein-Barr virus nuclear antigen 1 Hijacks the host kinase CK2 to disrupt PML nuclear bodies.
Sivachandran N, Cao JY, Frappier L
Journal of virology 2010 Nov;84(21):11113-23
Journal of virology 2010 Nov;84(21):11113-23
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
