618902
antibody from BioLegend
Targeting: TP63
EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 618902 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#618902, RRID:AB_2207171
- Product name
- Purified anti-p63 (TA)
- Antibody type
- Polyclonal
- Antigen
- Modified peptide
- Description
- p63 (TA) is a member of the p53 family. This protein has multiple isoforms TA p63-α, -β, -γ, and δN p63-α, -β, -γ. The molecular weight of the TA p63 isoforms α=77 kD, β=62 kD, and γ=56 kD. This nuclear protein is essential for limb formation, epidermal morphogenesis, epithelial stem cell regeneration; δN isoforms are antagonistic to p53; TA isoforms can transactivate p53 targets. The p63 δN isoforms repress TA isoforms; mutant p53 abrogates p63 transactivation This protein interacts with p53, p73, and the various p63 TA- and δN isoforms. The Poly6189 antibody recognizes human p63 TA isoforms and has been shown to be useful for Western blotting.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 200 µl
- Storage
- Upon receipt, store frozen at -20° C.
No comments: Submit comment
Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from 293E parent (lane 1) and 293E transfected with human P63(TA) (lane 2) using anti-P63(TA) antibody(poly6189).
- Conjugate
- Unconjugated