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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- MAB6752 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB6752, RRID:AB_10679628
- Product name
- KDM5A monoclonal antibody, clone 18E8
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against synthetic peptide of KDM5A.
- Isotype
- IgG
- Antibody clone number
- 18E8
- Storage
- Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation.
The retinoblastoma binding protein RBP2 is an H3K4 demethylase.
RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3.
Lopez-Bigas N, Kisiel TA, Dewaal DC, Holmes KB, Volkert TL, Gupta S, Love J, Murray HL, Young RA, Benevolenskaya EV
Molecular cell 2008 Aug 22;31(4):520-30
Molecular cell 2008 Aug 22;31(4):520-30
The retinoblastoma binding protein RBP2 is an H3K4 demethylase.
Klose RJ, Yan Q, Tothova Z, Yamane K, Erdjument-Bromage H, Tempst P, Gilliland DG, Zhang Y, Kaelin WG Jr
Cell 2007 Mar 9;128(5):889-900
Cell 2007 Mar 9;128(5):889-900
RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3.
Christensen J, Agger K, Cloos PA, Pasini D, Rose S, Sennels L, Rappsilber J, Hansen KH, Salcini AE, Helin K
Cell 2007 Mar 23;128(6):1063-76
Cell 2007 Mar 23;128(6):1063-76
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Supportive validation
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- Abnova Corporation (provider)
- Main image
- Experimental details
- Identification of KDM5A in crude cell extracts by western blotting with KDM5A monoclonal antibody, clone 18E8 (Cat # MAB6752).1. HeLa control siRNA2. HeLa KDM5A siRNA3. MCF-74. U-2 OS5. NIH/3T36. J1 (mouse ES)
